Water scarcity is rapidly increasing in many regions. In a novel, multi-model assessment, we examine how human interventions (HI: land use and land cover change, man-made reservoirs and human water ...use) affected monthly river water availability and water scarcity over the period 1971 - 2010. Here we show that HI drastically change the critical dimensions of water scarcity, aggravating water scarcity for 8.8%(7.4 - 16.5 %) ) of the global population but alleviating it for another 8.3 % (6.4 -15.8 %). Positive impacts of HI mostly occur upstream, whereas HI aggravate water scarcity downstream; HI cause water scarcity to travel downstream. Attribution of water scarcity changes to HI components is complex and varies among the hydrological models. Seasonal variation in impacts and dominant HI components is also substantial. A thorough consideration of the spatially and temporally varying interactions among HI components and of uncertainties is therefore crucial for the success of water scarcity adaptation by HI.
Probiotics are suggested to improve depressive symptoms via the microbiota-gut-brain axis. We have recently shown a beneficial clinical effect of probiotic supplementation in patients with ...depression. Their underlying neural mechanisms remain unknown.
A multimodal neuroimaging approach including diffusion tensor imaging, resting-state functional MRI, and arterial spin labeling was used to investigate the effects of a four-weeks probiotic supplementation on fronto-limbic brain structure, function, and perfusion and whether these effects were related to symptom changes.
Thirty-two patients completed both imaging assessments (18 placebo and 14 probiotics group). Probiotics maintained mean diffusivity in the left uncinate fasciculus, stabilized it in the right uncinate fasciculus, and altered resting-state functional connectivity (rsFC) between limbic structures and the temporal pole to a cluster in the precuneus. Moreover, a cluster in the left superior parietal lobule showed altered rsFC to the subcallosal cortex, the left orbitofrontal cortex, and limbic structures after probiotics. In the probiotics group, structural and functional changes were partly related to decreases in depressive symptoms.
This study has a rather small sample size. An additional follow-up MRI session would be interesting for seeing clearer changes in the relevant brain regions as clinical effects were strongest in the follow-up.
Probiotic supplementation is suggested to prevent neuronal degeneration along the uncinate fasciculus and alter fronto-limbic rsFC, effects that are partly related to the improvement of depressive symptoms. Elucidating the neural mechanisms underlying probiotics' clinical effects on depression provide potential targets for the development of more precise probiotic treatments.
•Probiotic add-on intervention improved depressive symptoms in patients.•However, underlying neural mechanisms still remain unknown.•Probiotics impact fronto-limbic structure and function.•These brain changes are partly associated with clinical improvements.
River flow regimes, including long-term average flows, seasonality, low flows, high flows and other types of flow variability, play an important role for freshwater ecosystems. Thus, climate change ...affects freshwater ecosystems not only by increased temperatures but also by altered river flow regimes. However, with one exception, transferable quantitative relations between flow alterations and ecological responses have not yet been derived. While discharge decreases are generally considered to be detrimental for ecosystems, the effect of future discharge increases is unclear. As a first step towards a global-scale analysis of climate change impacts on freshwater ecosystems, we quantified the impact of climate change on five ecologically relevant river flow indicators, using the global water model WaterGAP 2.1g to simulate monthly time series of river discharge with a spatial resolution of 0.5 degrees. Four climate change scenarios based on two global climate models and two greenhouse gas emissions scenarios were evaluated. We compared the impact of climate change by the 2050s to the impact of water withdrawals and dams on natural flow regimes that had occurred by 2002. Climate change was computed to alter seasonal flow regimes significantly (i.e. by more than 10%) on 90% of the global land area (excluding Greenland and Antarctica), as compared to only one quarter of the land area that had suffered from significant seasonal flow regime alterations due to dams and water withdrawals. Due to climate change, the timing of the maximum mean monthly river discharge will be shifted by at least one month on one third on the global land area, more often towards earlier months (mainly due to earlier snowmelt). Dams and withdrawals had caused comparable shifts on less than 5% of the land area only. Long-term average annual river discharge is predicted to significantly increase on one half of the land area, and to significantly decrease on one quarter. Dams and withdrawals had led to significant decreases on one sixth of the land area, and nowhere to increases. Thus, by the 2050s, climate change may have impacted ecologically relevant river flow characteristics more strongly than dams and water withdrawals have up to now. The only exception refers to the decrease of the statistical low flow Q90, with significant decreases both by past water withdrawals and future climate change on one quarter of the land area. However, dam impacts are likely underestimated by our study. Considering long-term average river discharge, only a few regions, including Spain, Italy, Iraq, Southern India, Western China, the Australian Murray Darling Basin and the High Plains Aquifer in the USA, all of them with extensive irrigation, are expected to be less affected by climate change than by past anthropogenic flow alterations. In some of these regions, climate change will exacerbate the discharge reductions, while in others climate change provides opportunities for reducing past reductions. Emissions scenario B2 leads to only slightly reduced alterations of river flow regimes as compared to scenario A2 even though emissions are much smaller. The differences in alterations resulting from the two applied climate models are larger than those resulting from the two emissions scenarios. Based on general knowledge about ecosystem responses to flow alterations and data related to flow alterations by dams and water withdrawals, we expect that the computed climate change induced river flow alterations will impact freshwater ecosystems more strongly than past anthropogenic alterations.
The cosmic-ray experiment KASCADE Antoni, T; Apel, W.D; Badea, F ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
11/2003, Letnik:
513, Številka:
3
Journal Article
Recenzirano
KASCADE has been designed to measure air showers of primary cosmic-ray energies in the PeV region and to investigate the
knee phenomenon in the all-particle energy spectrum. Several observations are ...measured simultaneously for each event by different detector systems. The experiment started to take data in 1996 and has been completed and extended since then. The individual detector systems and their performances are described. Also, the experience in long-term operation of the experiment and the interplay between different components is outlined.
Irrigation intensifies land use by increasing crop yield but also impacts water resources. It affects water and energy balances and consequently the microclimate in irrigated regions. Therefore, ...knowledge of the extent of irrigated land is important for hydrological and crop modelling, global change research, and assessments of resource use and management. Information on the historical evolution of irrigated lands is limited. The new global historical irrigation data set (HID) provides estimates of the temporal development of the area equipped for irrigation (AEI) between 1900 and 2005 at 5 arcmin resolution. We collected sub-national irrigation statistics from various sources and found that the global extent of AEI increased from 63 million ha (Mha) in 1900 to 111 Mha in 1950 and 306 Mha in 2005. We developed eight gridded versions of time series of AEI by combining sub-national irrigation statistics with different data sets on the historical extent of cropland and pasture. Different rules were applied to maximize consistency of the gridded products to sub-national irrigation statistics or to historical cropland and pasture data sets. The HID reflects very well the spatial patterns of irrigated land as shown on historical maps for the western United States (around year 1900) and on a global map (around year 1960). Mean aridity on irrigated land increased and mean natural river discharge on irrigated land decreased from 1900 to 1950 whereas aridity decreased and river discharge remained approximately constant from 1950 to 2005. The data set and its documentation are made available in an open-data repository at https://mygeohub.org/publications/8 (doi:10.13019/M20599).
Treating and reusing municipal wastewater for urban agriculture raises water productivity. This paper developed a methodology to quantify water flows and productivity of a proposed infrastructure ...including water supply, sanitation, wastewater treatment and water reuse for agriculture. The methodology consists in calculating the pathogen reduction achieved with wastewater treatment, designing a crop scheme for the irrigation with treated water, modeling irrigation requirements and quantifying water flows with mathematical material flow analysis. This methodology was applied for the current state and with the planned facility in semi-arid Namibia. This infrastructure has the potential to raise water productivity by +10% as household water use increases with improved sanitation. Compared to not reusing the water for agriculture, water productivity can be raised by +39%. This methodology allowed the consideration of the impact of facility user behavior on water flows and found that water productivity increases less than computed with a fixed wastewater inflow.
Within this work we demonstrate different Anodic Oxidation processes to achieve a broad variety of nanostructures on titanium and the titanium alloy Ti6Al4V for the use as medical implant surfaces. ...The influence of electrolyte, reaction time and voltage on the nanostructure formation is described as well as the transfer to microstructured surfaces. As electrolytes we investigate sulfuric and hydrofluoric acids with different concentrations. The resulting nanostructures reach from nano porosities over amorphous sponge like structures to self-assembled hexagonal nanotubes.
Within this work we demonstrate a UV-Lithography based method for the fabrication of microgrooves on titanium surfaces. The microgroove period, depth and profile form are easily controllable by ...process parameters. By controlled under-etching of a lithographically structured photo resist, different profile forms from nearly rectangular, over curvy/spiked to sinus-shaped forms with different amplitudes and sizes can be realized. The resulting microgrooves can be directly used as implant or implant abutment surfaces to enhance soft tissue integration or to create molds for cell/substrate interaction studies. Due to the lithographic process the whole method is highly controllable and reproducible.
► Using muon tracking we study muon production heights in cosmic ray air showers. ► The sensitivity of this quantity to the primary particle mass and energy is shown. ► The validity of hadronic ...interaction models used in simulations is discussed. ► An estimate of the cosmic ray mass composition in the studied energy range is given
A large area (128
m
2) muon tracking detector, located within the KASCADE experiment, has been built with the aim to identify muons (
E
μ
>
0.8
GeV) and their angular correlation in extensive air showers by track measurements under 18 r.l. shielding. Orientation of the muon track with respect to the shower axis is expressed in terms of the radial and tangential angles, which are the basic tools for all muon investigations with the tracking detector. By means of triangulation the muon production height is determined. Distributions of measured production heights are compared to CORSIKA shower simulations. Analysis of these heights reveals a transition from light to heavy cosmic ray primary particles with increasing shower energy in the energy region of the ‘Knee’ of the cosmic ray spectrum
Using data measured by the KASCADE-Grande air shower array, an upper limit to the flux of ultra-high energy gamma-rays in the primary cosmic-ray flux is determined. KASCADE-Grande measures the ...electromagnetic and muonic components for individual air showers in the energy range from 10 PeV up to 1 EeV. The analysis is performed by selecting air showers with low muon contents. A preliminary result on the 90% C.L. upper limit to the relative intensity of gamma-ray with respect to cosmic ray primaries is presented and compared with limits reported by other measurements.
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