Mit Wolfram und Lampe: Einen Zugang zu Ketonen bietet die photokatalytische Erzeugung von Acylradikalen aus Aldehyden und deren Abfangreaktion mit äquimolaren Mengen elektrophiler Alkene. Die ...Photokatalyse mit Tetrabutylammoniumdecawolframat ist auch bei niedrigen Temperaturen (−20 bis −50 °C) effektiv, was die Decarbonylierung der Radikale minimiert und die Acylierung mit hoch substituierten Aldehyden ermöglicht.
The study of historical documents is an important and complex branch of document analysis. Ancient manuscripts are often altered by time or environmental conditions and the availability of large data ...sets is not always guaranteed. In this work, we propose a new solution for the attribution of short historical documents based on both allographic and texture features. Paleographic data were used as reference during the development. Tests were conducted on Antonio Stradivari's relics, a collection of technical drawings and artifacts of the famous violin maker, currently held in "Museo del Violino" in Cremona (Italy), that contains his working notes. This data set is very complex, it contains only short writings (few text lines or words), faded or damaged areas, different supports (wood or paper), and various annotations added by the various owners of this collection during the centuries. Experimental results are promising showing an accuracy greater than 90% using short texts both as training and as target.
An amino acid mixture rich in branched-chain amino acids and poor in aromatic amino acids was infused in six cirrhotics with altered plasma amino acid profile and normal mental state. The effect on ...muscle protein catabolism, as measured by urinary excretion of 3-methylhistidine, was assessed during two consecutive 3-day period in which patients received the amino acid mixture alone or in a hypertonic dextrose solution. During a 3-day basal period, cirrhotics showed increased rates of 3-methylhistidine excretion as compared to six matched healthy subjects. Both treatments reduced urinary 3-methylhistidine to normal. During treatment, branched-chain amino acids failed to normalize, plasma aromatic amino acid concentrations and ammonia declined, and alanine increased. Branched-chain amino acids are mainly oxidized in skeletal muscle with production of alanine. Reduced muscle protein catabolism following amino acid infusion is consistent with the physiological role of branched-chain amino acids in suppressing protein breakdown and stimulating protein synthesis. Long-term therapy with branched-chain amino acid-enriched mixtures may prove useful in advanced cirrhotics with severe muscle wasting.
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1. The lysine salt of acetyl salicylic acid (ASA) at a dose equivalent to 400 mg/kg of acetyl salicylic acid (ASA) was intraperitoneally administered in rats.
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2. After 30 and 120min ASA did not ...modify the number of receptors nor the affinity of
3H8-OH-DPAT binding sites in pons and cerebral cortex. On the other hand, the receptor number in the cortex membranes decreased significantly using
3Hketanserin as ligand, while the receptor number in the pontine membranes did not change.
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3. These data support the involvement of central 5-HT receptors in the mode of action of ASA.
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