Pedunculate oak (
Quercus robur
L.) is one of the most important forest tree species in Europe, from both economic and ecological perspectives. Several studies indicate the possibility of using ...different species of the genus
Quercus
for afforestation of lands affected by industry, including trace-element polluted areas. The main objective of this research was to determine the Cd accumulation patterns of pedunculate oak seedlings subjected to various Cd treatments. Differences in Cd accumulation ability, mineral nutrients concentrations and observed damage upon Cd treatment of plants derived from different regions of origin are discussed. Obtained results suggest the possible use of pedunculate oak in cadmium phytostabilization.
.
A segmented Si-telescope and HPGe array, STARS-LIBERACE, was used to study the
156
Gd(
p
,
t
γ
)
154
Gd direct reaction by particle-
γ
coincidence spectroscopy. New cross sections with a 25MeV ...proton beam are reported and compared to previous (p,t) and (t,p) studies. Furthermore, additional evidence for coexisting
K
π
=
0
1
+
,
2
1
+
and
0
2
+
,
2
2
+
configurations at
N
= 90 is presented. Direct and indirect population patterns of the low-lying states are also explored. Review of the new and existing evidence favors an interpretation based on a configuration-dependent pairing interaction. The weakening of monopole pairing strength and an increase in quadrupole pairing strength could bring 2p-2h
0
+
states below
2
Δ
. This may account for a large number of the low-lying
0
+
states observed in two-nucleon transfer reactions. A hypothesis for the origin of the
0
2
+
and
0
3
+
states is provided.
Multimodal imaging in Pheochromocytoma Müssig, K; Dittmann, H; Dudziak, K ...
RöFo : Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebende Verfahren
183, Številka:
11
Journal Article
In the absence of preoperative somatostatin receptor ( SST) scans, knowledge of immunohistochemical SST2 tumor expression may help predicting the success of somatostatin analogue-based follow-up ...studies and treatment of neuroendocrine tumors (NET). We studied the association between SST immunostaining and tracer uptake in (111)In-DTPA octreotide (DTPAOC) scintigraphy and (68)Ga-DOTA-D-Phe(1)-Tyr(3)-octreotide (DOTATOC) positron emission tomography (PET)/computed tomography (CT). Retrospective analy-sis of 36 NET patients was carried out. In 40 tumors, immunohistochemical SST2, SST3, and SST5 expressions were analyzed using a pathological scoring, applying monoclonal ( SST2) or polyclonal antibodies (SST3, SST5). In 14 lesions, (111)In-DTPAOC uptake was assessed by a semiquantitative score. In 26 tumors, (68)Ga-DOTATOC PET/CT was quantified using an uptake score and maximal standard uptake value (SUV(max)). Combined and separate qualitative analysis of SST scans revealed significant associations between increased tracer uptake and immunohistochemical SST2 detection (combined: rho=0.56, p=0.0002, (111)In-DTPAOC: rho=0.63, p=0.0152, and (68)Ga-DOTATOC: rho=0.52, p=0.0065, respectively). In contrast, SST3 and SST5 immunostaining was not associated with tracer uptake (all p>0.14). The semiquantitative immunohistochemical score for SST2 was associated with the (68)Ga-DOTATOC uptake score and SUV (max) values (rho=0.67, p=0.0002 and rho=0.63, p=0.0010, respectively), but not with the (111)In-DTPAOC uptake score (rho=0.24, p=0.4). In patients without preoperative SST scans, knowledge of immunohistochemical SST2 expression may help estimating the value of SST imaging in the clinical follow-up, in particular in those lesions with positive SST2 immunostaining. Negativity for SST2, however, does not rule out tracer uptake in some patients, with heterogeneous SST2 expression within the tumor as a potential explanation.
A segmented Si-telescope and HPGe array, STARS-LIBERACE, was used to study the 156Gd(p, tγ)154Gd direct reaction by particle- γ coincidence spectroscopy. New cross sections with a 25MeV proton beam ...are reported and compared to previous (p,t) and (t,p) studies. Furthermore, additional evidence for coexisting Kπ=01+,21+ and 02+, 22+ configurations at N = 90 is presented. Direct and indirect population patterns of the low-lying states are also explored. Review of the new and existing evidence favors an interpretation based on a configuration-dependent pairing interaction. The weakening of monopole pairing strength and an increase in quadrupole pairing strength could bring 2p-2h 0+ states below 2 Δ. This may account for a large number of the low-lying 0+ states observed in two-nucleon transfer reactions. A hypothesis for the origin of the 02+ and 03+ states is provided.
For many years, arch-support orthotics have been prescribed for individuals with discomfort and/or abnormal skeletal alignments in the structures of the lower extremity. Recently there has been an ...increased interest in promoting semi-rigid orthotics as an ergonomic aid for asymptomatic workers who must stand all day at their workplace. A laboratory study was performed to assess the biomechanical impact of prefabricated semi-rigid orthotics on asymptomatic individuals. Ten subjects wore semi-rigid arch-support orthotics (experimental condition) for two months and flexible polyurethane/Sorbothane ® shoe inserts (control condition) for two months. Throughout this 18-week testing period, the subjects returned to the lab to perform a battery of assessment tests at regularly scheduled intervals. These tests examined subject strength, standing posture, stability, fatigue effects, and body part discomfort. The results of this study showed no significant changes in the strength, posture, or stability as a function of insert type. The subjects reported a reduction in low-back discomfort along with an increase in foot discomfort during a fatiguing exertion task while wearing the semi-rigid orthotics as compared to the control condition.
Although several studies have focused on allergic sensitization by dendritic cells, to date it is still open under which conditions these antigen presenting cells are able to induce an allergic ...immune response. Therefore we examined whether dendritic cells generated from bone marrow in the presence of GMCSF (BMDC) and pulsed with LPS-free allergen are able to induce an allergic immune response or further activation by a danger signal is required.
Our study reveals that BMDC pulsed with LPS-free ovalbumine did not induce an allergic immune response. However, when BMDC were activated with low dose LPS during pulsing with allergen, these cells express an inflammatory set of cytokines and co-stimulatory molecules like CD86 and OX40L. Moreover activated cells were able to prime mice for massive eosinophilic inflammation of the lung, airway hyper-reactivity, IgE production and production of Th2 cytokines by lymphocytes. Blocking experiments showed that expression of OX40L is not involved in induction of Th2 response. Interestingly, BMDC that were activated with high dose of LPS loose their Th2 sensitizing capacity. Instead these cells induce a Th17 type immune response.
We conclude that presentation of allergen by dendritic cells generated with GMCSF is not sufficient to lead to induction of allergic immune response. Further activation of BMDC is required to prime mice for allergic immune response. Here we demonstrate that LPS is a suitable stimulus. However, when cells were activated with high dose LPS they tend to induce a Th17 response.
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