A model resulting in charge ordering (CO) similar to that observed in cuprate superconductors is under study. It includes strong long-range electron-phonon interaction (EPI) and high density of ...correlated carriers. Coexistence of large bipolarons and delocalized carriers is a feature of such system. We develop generalized variation method to calculate the bipolaron size (CO period) in the ground normal state of such system at various doping. The approach allows the revealing of a possible physical reason of strongly different doping behavior of the CO wave vector in different cuprates. Obtained doping dependences of the CO period and temperature of the CO decay demonstrate quantitative agreement with those observed in cuprates. Predicted in the suggested approach ratio of the CO wave vector to the wave vector of the high-energy anomaly (HEA) in ARPES spectrum is in consent with that in cuprates. Calculated resonant x-rays scattering on the CO emerging in the model is in good agreement with experiments on cuprates including the asymmetry of the CO peaks' cross-section. A gap arises in the spectrum of delocalized carriers near antinodal direction due to their scattering on the periodic potential created by autolocalized carriers, analogously to photon crystal effect.
The interaction between NH3, CH4 and NO under different conditions of interest for combustion applications is analyzed, from both experimental and kinetic modeling points of view. Reduction of NO by ...reburn and by SNCR (selective non-catalytic reduction) strategies is evaluated, through an extense systematic study of the influence of the main variables of interest for NO reduction, by means of laboratory flow-reactor experiments at atmospheric pressure. Variables analyzed include: temperature in the 700 to 1500 K range, air stoichiometry from fuel-rich (λ = 0.31) to fuel-lean conditions (λ = 2.21), NH3/CH4 ratio in the 0.4 to 10.78 range, NH3/NO ratio in the 0.49 to 2.60 range the, and CH4/NO ratio in the 0.37 to 1.98 range, dilution level, and bath gas by using nitrogen and argon, the latter to allow the precise determination of nitrogen balances. Results are interpreted using a literature reaction mechanism, together with reaction pathway analysis tools, and the main findings are discussed. Results indicate that ammonia promotes the conversion of methane, while methane inhibits the conversion of ammonia, due to the competition for radicals of both components in the mixture. The interaction of ammonia and methane implies that the reduction of NO by NH3/CH4 mixtures is comparatively lower than the reduction obtained by NH3 and CH4 independently. Implications for practical applications of the reduction of NO by the studied mixtures are discussed.
The aim of this study was to assess the effects of team training on operational efficiency during outpatient MRI.
In this institutional review board-approved, HIPAA-compliant study, six MRI ...outpatient sites of a midwestern hospital system were randomized to serve as controls or have their teams trained in advanced communication skills. The fourth quarter of fiscal year 2015 was the trial baseline. The trial ended in the third quarter (Q3) of fiscal year 2016 (FY16). Equipment utilization (completed scans/available slots), hourly scan rates (total orders completed per machine per hour of operation), and no-show rates stratified by time were analyzed using the Cochran-Mantel-Haenszel method, with individual comparisons performed with Bonferroni correction.
The study encompassed 27,425 MRI examinations. Overall volume peaked at baseline and then declined over the following quarters. Compared with baseline, untrained sites experienced significant drops in equipment utilization (P < .01 for the first quarter of FY16 and P < .0001 for the second quarter of FY16 and Q3 FY16), decreasing from 77% to 65% over the study period, corresponding to a decrease from 1.15 to 0.97 in hourly scan rates. For trained sites, these metrics showed no significant change, with maintenance of hourly scan rates of 1.23 and 1.27 and equipment utilization rates of 83% and 85% between baseline and Q3 FY16. No-show rates remained stable at trained sites but increased at untrained sites in the last two quarters (P < .05). Nationally benchmarked patient satisfaction percentile ranking gradually increased at trained sites from 56th at baseline to 70th and successively decreased at untrained sites from 66th to 44th.
MRI outpatient facilities trained in advanced communication techniques may have more favorable operational efficiency than untrained sites in a saturated market.
Macrophage activation syndrome in COVID-19 Grigorieva, K. N.; Bitsadze, V. O.; Khizroeva, J. Kh ...
Акушерство, гинекология и репродукция,
07/2021, Letnik:
15, Številka:
3
Journal Article
Recenzirano
Odprti dostop
The novel coronavirus epidemic is characterized by high rates of morbidity and relatively high mortality. Laboratory test results in patients include leukopenia, an increase in liver function tests ...and ferritin levels reaching hundreds, and sometimes thousands of units. These data remind us about the macrophage activation syndrome (MAC). Secondary hemophagocytic lymphohistiocytosis syndrome, MAC, which pathogenesis is based on a defect in the mechanisms of T-cell cytotoxicity and decreased level of natural killer cells associated with the defect in the perforin-encoding gene as well as hyperproduction of a number of cytokines – interleukin (IL)-1â, tumor necrosis factor-á, etc. by T-lymphocytes and histiocytes, indirectly leading to the activation of macrophages and production of proinflammatory cytokines, in particular IL-6 hyperproduction. MAC is one of "hyperferritinemic syndromes". These disorders have similar clinical and laboratory manifestations, and they also respond to similar treatments, suggesting that hyperferritinemia may be involved in the overall pathogenesis and is characterized by elevated ferritin level and cytokine storm. Despite the fact that data on the immune and inflammatory status in patients with COVID-19 have only started to appear, it is already clear that hyperinflammation and coagulopathy affect the disease severity and increase the risk of death in patients infected with SARS-CoV-2. Hence, understanding the pathogenesis of the novel coronavirus infection can help in its early diagnostics and treatment.
We present the observation of doubly-produced $J/\psi$ mesons with the D0 detector at Fermilab in $p\bar{p}$ collisions at $\sqrt{s}=1.96$ TeV. The production cross section for both singly and ...doubly-produced $J/\psi$ mesons is measured using a sample with an integrated luminosity of 8.1~fb$^{-1}$. For the first time, the double $J/\psi$ production cross section is separated into contributions due to single and double parton scatterings. Using these measurements, we determine the effective cross section \sigteff, a parameter characterizing an effective spatial area of the parton-parton interactions and related to the parton spatial density inside the nucleon.
Drell-Yan lepton pairs produced in the process pp¯→ℓ+ℓ−+X through an intermediate γ*/Z boson have an asymmetry in their angular distribution related to the spontaneous symmetry breaking of the ...electroweak force and the associated mixing of its neutral gauge bosons. The CDF and D0 experiments have measured the effective-leptonic electroweak mixing parameter sin2θefflept using electron and muon pairs selected from the full Tevatron proton-antiproton data sets collected in 2001-2011, corresponding to 9–10 fb−1 of integrated luminosity. The combination of these measurements yields the most precise result from hadron colliders, sin2θefflept=0.23148±0.00033. This result is consistent with, and approaches in precision, the best measurements from electron-positron colliders. The standard model inference of the on-shell electroweak mixing parameter sin2θW, or equivalently the W-boson mass MW, using the zfitter software package yields sin2θW=0.22324±0.00033 or equivalently, MW=80.367±0.017 GeV/c2.
The effect of substrate temperature on the direct current magnetron‐sputtered zirconium oxide (ZrO2) dielectric films was investigated. Stoichiometric of the ZrO2 thin films was obtained at an oxygen ...partial pressure of 4.0 × 10−2 Pa. X‐ray diffraction studies revealed that the crystallite size in the layer was increased from 4.8 to 16.1 nm with increase of substrate temperature from 303 to 673 K. Metal‐oxide‐semiconductor devices were fabricated on ZrO2/Si stacks with Al gate electrode. The dielectric properties of ZrO2 layer and interface quality at ZrO2/Si were significantly influenced by the substrate temperature. The dielectric constant increased from 15 to 25, and the leakage current density decreased from 0.12 × 10−7 to 0.64 × 10−9 A cm−2 with the increase of substrate temperature from 303 to 673 K.
Objective The objective of the study was to compare neonatal morbidity and long-term neurodevelopmental outcome between very preterm infants with placental underperfusion and very preterm infants ...with histological chorioamnionitis. Study Design We measured the mental and motor development at age 2 and 7 years in 51 very preterm infants with placental underperfusion and 21 very preterm infants with histological chorioamnionitis. Results At 2 years, very preterm infants with placental underperfusion had poorer mental development than very preterm infants with histological chorioamnionitis (mean SD 90.8 18.3 vs 104.1 17.2, adjusted d = 1.12, P = .001). Motor development was not different between both groups (92.8 17.2 vs 96.8 8.7, adjusted d = 0.52, P = .12). At 7 years, large, although nonsignificant, effects were found for better mental and motor development and fewer behavioral problems in infants with histological chorioamnionitis. Conclusion Placental pathology contributes to variance in mental development at 2 years and should be taken into account when evaluating neurodevelopmental outcome of very preterm infants.
Thread-parallelisation and single-instruction multiple data (SIMD) "vectorisation" of software components in HEP computing has become a necessity to fully benefit from current and future computing ...hardware. In this context, the Geant-Vector GPU simulation project aims to re-engineer current software for the simulation of the passage of particles through detectors in order to increase the overall event throughput. As one of the core modules in this area, the geometry library plays a central role and vectorising its algorithms will be one of the cornerstones towards achieving good CPU performance. Here, we report on the progress made in vectorising the shape primitives, as well as in applying new C++ template based optimisations of existing code available in the Geant4, ROOT or USolids geometry libraries. We will focus on a presentation of our software development approach that aims to provide optimised code for all use cases of the library (e.g., single particle and many-particle APIs) and to support different architectures (CPU and GPU) while keeping the code base small, manageable and maintainable. We report on a generic and templated C++ geometry library as a continuation of the AIDA USolids project. The experience gained with these developments will be beneficial to other parts of the simulation software, such as for the optimisation of the physics library, and possibly to other parts of the experiment software stack, such as reconstruction and analysis.
This paper is describing an investigation of surfactants influence on zinc sulfide wetting by non-polar liquids and sphalerite concentrates pressure leaching parameters. Zinc sulfide preferential ...wettability by oil was tested in presence anionic surfactants with different chemical structures. Interfacial tension was determinated by the maximum liquid drop volume method. It allows to determine surfactant potential effectivity on pressure leaching of sphalerite concentrate. It is found that SDBS decreases zinc sulfide wettability by non-polar liquids in a greater degree than SDS and Ls. Combined addition of Ls and SDBS allowed to receive residues with optimal coarseness, eliminate pellet formation and increase zinc extraction.