The Cherenkov Telescope Array (CTA) is a future gamma-ray observatory that is planned to significantly improve upon the sensitivity and precision of the current generation of Cherenkov telescopes. ...The observatory will consist of several dozens of telescopes with different sizes and equipped with different types of cameras. Of these, the FlashCam camera system is the first to implement a fully digital signal processing chain which allows for a traceable, configurable trigger scheme and flexible signal reconstruction. As of autumn 2016, a prototype FlashCam camera for the medium-sized telescopes of CTA nears completion. First results of the ongoing system tests demonstrate that the signal chain and the readout system surpass CTA requirements. The stability of the system is shown using long-term temperature cycling.
•A full-scale prototype of the FlashCam Cherenkov camera is in operation.•System level testing and characterisation in a dark room is ongoing.•The performances of the data acquisition and the signal chain have been verified.•The system is stable over long periods and robust against temperature variations.
The Cherenkov Telescope Array (CTA) will be the next generation ground-based observatory for cosmic gamma rays. The FlashCam camera for its mid-size telescope introduces a new concept, with a modest ...sampling rate of 250 MS/s, that enables a continuous digitization as well as event buffering and trigger processing using the same front-end FPGAs. The high performance Ethernet-based readout provides a dead-time free operation for event rates up to 30 kHz corresponding to a data rate of 2.0 GByte/s sent to the camera server. We present the camera design and the current status of the project.
Trigger performance verification of the FlashCam prototype camera Sailer, S.; Werner, F.; Hermann, G. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
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FlashCam is a camera proposed for the medium-sized telescopes of the Cherenkov Telescope Array (CTA). We compare camera trigger rates obtained from measurements with the camera prototype in the ...laboratory and Monte Carlo simulations, when scanning the parameter space of the fully-digital trigger logic and the intensity of a continuous light source mimicking the night sky background (NSB) during on-site operation. The comparisons of the measured data results to the Monte Carlo simulations are used to verify the FlashCam trigger logic and the expected trigger performance.
FlashCam is a camera proposed for the medium-sized telescopes of the Cherenkov Telescope Array (CTA). We compare camera trigger rates obtained from measurements with the camera prototype in the ...laboratory and Monte-Carlo simulations, when scanning the parameter space of the fully-digital trigger logic and the intensity of a continuous light source mimicking the night sky background (NSB) during on-site operation. The comparisons of the measured data results to the Monte-Carlo simulations are used to verify the FlashCam trigger logic and the expected trigger performance.
The Cherenkov Telescope Array (CTA) is a future gamma-ray observatory that is planned to significantly improve upon the sensitivity and precision of the current generation of Cherenkov telescopes. ...The observatory will consist of several dozens of telescopes with different sizes and equipped with different types of cameras. Of these, the FlashCam camera system is the first to implement a fully digital signal processing chain which allows for a traceable, configurable trigger scheme and flexible signal reconstruction. As of autumn 2016, a prototype FlashCam camera for the medium-sized telescopes of CTA nears completion. First results of the ongoing system tests demonstrate that the signal chain and the readout system surpass CTA requirements. The stability of the system is shown using long-term temperature cycling.
The FlashCam group is currently preparing photomultiplier-tube based cameras proposed for the medium-sized telescopes (MST) of the Cherenkov Telescope Array (CTA). The cameras are designed around the ...FlashCam readout concept which is the first fully-digital readout system for Cherenkov cameras, based on commercial FADCs and FPGAs as key components for the front-end electronics modules and a high performance camera server as back-end. This contribution describes the progress of the full-scale FlashCam camera prototype currently under construction, as well as performance results also obtained with earlier demonstrator setups. Plans towards the production and implementation of FlashCams on site are also briefly presented.
FlashCam is a Cherenkov camera development project centered around a fully digital trigger and readout scheme with smart, digital signal processing, and a "horizontal" architecture for the ...electromechanical implementation. The fully digital approach, based on commercial FADCs and FPGAs as key components, provides the option to easily implement different types of triggers as well as digitization and readout scenarios using identical hardware, by simply changing the firmware on the FPGAs. At the same time, a large dynamic range and high resolution of low-amplitude signals in a single readout channel per pixel is achieved using compression of high amplitude signals in the preamplifier and signal processing in the FPGA. The readout of the front-end modules into a camera server is Ethernet-based using standard Ethernet switches. In its current implementation, data transfer and backend processing rates of ~3.8 GBytes/sec have been achieved. Together with the dead-time-free front end event buffering on the FPGAs, this permits the cameras to operate at trigger rates of up to several tens of kHz. In the horizontal architecture of FlashCam, the photon detector plane (PDP), consisting of photon detectors, preamplifiers, high voltage-, control-, and monitoring systems, is a self-contained unit, which is interfaced through analogue signal transmission to the digital readout system. The horizontal integration of FlashCam is expected not only to be more cost efficient, it also allows PDPs with different types of photon detectors to be adapted to the FlashCam readout system. This paper describes the FlashCam concept, its verification process, and its implementation for a 12 m class CTA telescope with PMT-based PDP.
The future Cherenkov Telescope Array (CTA) will consist of several tens of telescopes of different mirror sizes. CTA will provide next generation sensitivity to very high energy photons from few tens ...of GeV to >100 TeV. Several focal plane instrumentation options are currently being evaluated inside the CTA consortium. In this paper, the current status of the FlashCam prototyping project is described. FlashCam is based on a fully digital camera readout concept and features a clean separation between photon detector plane and signal digitization/triggering electronics.
Striated skeletal muscle cells from humans represent a valuable source for in vitro studies of the motoric system as well as for pathophysiological investigations in the clinical settings. Myoblasts ...can readily be grown from human muscle tissue. However, if muscle tissue is unavailable, myogenic cells can be generated from human induced pluripotent stem cells (hiPSCs) preferably without genetic engineering. Our study aimed to optimize the generation of hiPSCs derived myogenic cells by employing selection of CD34 positive cells and followed by distinct, stepwise culture conditions. Following the expansion of CD34 positive single cells under myogenic cell culture conditions, serum deprived myoblast-like cells finally fused and formed multinucleated striated myotubes that expressed a set of key markers for muscle differentiation. In addition, these myotubes contracted upon electrical stimulation, responded to acetylcholine (Ach) and were able to generate action potentials. Finally, we co-cultured motoneurons and myotubes generated from identical hiPSCs cell lines. We could observe the early aggregation of acetylcholine receptors in muscle cells of immature co-cultures. At later stages, we identified and characterised mature neuromuscular junctions (NMJs). In summary, we describe here the successful generation of an iPS cell derived functional cellular system consisting of two distinct communicating cells types. This in vitro co-culture system could therefore contribute to research on diseases in which the motoneurons and the NMJ are predominantly affected, such as in amyotrophic lateral sclerosis or spinal muscular atrophy.
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•Method to generate myoblasts derived from hiPSC cells by CD34 selection compared to hiPSC myoblast by PAX7 over expression.•Cells expressed myoblast markers and differentiate into multinucleated-striated myotubes.•hiPSCs derived myotubes were functional: contract, to respond to acetylcholine, generate an action potential.•Acetylcholine receptor aggregation and mature neuromuscular junctions were observed indicating a motor-unit formation.
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