Um terminal inaugural Fabbri, Paolo
Estudos semióticos,
12/2017, Letnik:
13, Številka:
2
Journal Article
Odprti dostop
O texto retoma o primeiro Dicionário de Semiótica, aquele publicado por Greimas e Courtés em 1979, e também o tomo II, para discutir a atualidade de suas contribuições no seio das ciências da ...linguagem. Tanto as bases do projeto que inspira a sua elaboração, quanto sua singularidade em relação às outras propostas, são então retomadas ao longo do artigo para lançar luz sobre o alcance metodológico da teoria e os avanços que permitiu no estudo dos processos de sentido.
The image of nude appears to have ‘moved’, both because of the shift in our gaze and its point of reference. That is, unless this ‘negative emphasis’ is seen only as the uncritical acceptance of ...that ‘polarizing question’ that declared the end of Classical art and the decisive advent of modernity or as the effect of an hermeneutic excess ‒ of a philosophical definition of the nude implicit in our figurative culture – is it now the moment to go beyond the observation of the canonic nude and to develop new approaches to nudity? Despite its obviousness, the nude, too, is difficult to define. Where does the garment begin and the gown end? The skin and the flesh? How are we to describe the forces, movements and gestures of the body and its involucres? I will argue that the nude should be neither a pictorial genre nor a philosophical concept, but a «thought of the body» (De Chirico). It is an aesthetic figure with the power of affection and perception, but also a conceptual figure. It is not a ‘critical operator’ ‒ a cognitive ‘walk-on’ or extra ‒ but an actor with the power of speech, capable of forming and transforming new relationships with observers.
Subsurface water processes are principle triggering and driving factors during slope movements. However, the hydraulic properties that drive groundwater flow along the slope remain poorly understood. ...Moreover, landslide deposits are often characterized by layering and fissures that cause high heterogeneity in the distribution of hydraulic properties. This heterogeneity leads to great uncertainty in the prediction of groundwater flow paths. This study aimed to improve understanding of hydraulic and transport properties of deep earth slides and to identify preferential flow directions inside the landslide body. A dye tracer test was used to estimate transport parameters and characterize groundwater flow paths. The results indicate that in the studied landslide, two groundwater flow types exist and are related to the presence of fissured rock blocks and debris horizons embedded in a fine matrix. The estimated low groundwater flow velocity has rarely been estimated in other studies of this landslide type. The groundwater flow direction appears to be mainly influenced by the failure surface shape and differs from the sliding direction. Our results differ from those in other landslide studies and improve our knowledge of groundwater flow properties in deep earth slides; furthermore, they offer a new contribution to slope stability analyses and formula, and to the effective design of mitigation strategies.
•Subsurface water drives earth slides, but hydraulic properties are heterogeneous.•Dye tracer tests can track landslide groundwater flow & hydrogeological properties.•Fissured rocks and debris horizons in a fine matrix control groundwater flows.•Groundwater flow velocity in the Montecagno deep earth slide is very low (~ 1 m/d).•Subsurface layers, heterogeneity & shear surface shape influence groundwater flow.
The Venetian Plain is known for areas with high concentrations of arsenic (As) in groundwater (up to more than 400 μg/L; exceptionally 647 μg/L, in selected areas). A study area was chosen, north of ...Padua, which exhibits typical residential, industrial, and agricultural characteristics similar to most Western countries and lacks hydrothermal, volcanic, or anthropogenic sources of arsenic. The pilot area was the focus of several studies which are reviewed in this note. The objectives of the studies were to verify the distribution of As concentrations in groundwater and sediments (mineralogical and geochemical analysis of groundwater sediments and of filtered and unfiltered groundwater) and to model the mobility of arsenic arising from water-rock interaction. The grain size of aquifer reservoirs includes gravel, sand, silt, and clay. The amount of organic matter in the aquifer sediments of the study area seems peculiar (higher) compared to other plains in the world; it influences the redox potential and the relative concentration of As in groundwater. Arsenic contamination in groundwater and redox conditions varied greatly in the area. Groundwater under oxidizing and highly reducing conditions had much lower arsenic concentrations compared to groundwater under intermediate reducing conditions. Arsenic minerals (such as realgar-pararealgar) occur in aquifer sediments and they were documented in the studied materials by different analytical techniques for the first time in the context of the Italian plains. Since these minerals are rare throughout the world in plain sediments not affected by volcanic or hydrothermal activity, their occurrence is a distinctive feature of the Venetian Plain aquifer. These arsenic minerals were found in peat sediments of the study area, consistent with geochemical modeling results, which require highly reducing conditions for their precipitation from groundwater. Modeling suggests that under oxidizing and up to slightly reducing conditions (from 200 mV to -50 mV), arsenic is adsorbed on solid phases, but a further decrease in redox potential leads arsenic desorption from solids and consequent groundwater contamination (from -50 mV to -250 mV). If the redox potential becomes even more negative (below -250 mV), geochemical conditions are favorable to the formation of arsenic sulfides. The precipitation of the realgar-pararealgar phases, predicted by the geochemical model, proceeds by extracting arsenic from the groundwater and quantitatively accounts for the lower arsenic concentration measured in the highly reducing groundwater of the study area.
The baseline value of neutrophil to lymphocyte ratio (NLR) has been found to be prognostic in patients with metastatic castration resistant prostate cancer (CRPC). We evaluated the impact of baseline ...NLR and its change in patients receiving enzalutamide. We included consecutive metastatic CRPC patients treated with enzalutamide after docetaxel and studies the change of NLR (>3 vs ≤3) after week 4 and 12 weeks. Progression-free survival (PFS), overall survival (OS) and their 95% Confidence Intervals (95% CI) were estimated by the Kaplan-Meier method and compared with the log-rank test. The impact of NLR on PFS and OS was evaluated by Cox regression analyses and on prostate-specific antigen response rates (PSA RR; PSA decline >50%) were evaluated by binary logistic regression. Data collected on 193 patients from 9 centers were evaluated. Median age was 73.1 years (range, 42.8-90.7). The median baseline NLR was 3.2. The median PFS was 3.2 months (95% CI = 2.7-4.2) in patients with baseline NLR >3 and 7.4 months (95% CI = 5.5-9.7) in those with NLR ≤3, p < 0.0001. The median OS was 10.4 months (95% CI = 6.5-14.9) in patients with baseline NLR >3 and 16.9 months (95% CI = 11.2-20.9) in those with baseline NLR ≤3, p < 0.0001. In multivariate analysis, changes in NLR at 4 weeks were significant predictors of both PFS hazard ratio (HR) 1.24, 95% confidence interval (95% CI) 1.07-1.42, p = 0.003, and OS (HR 1.29, 95% CI 1.10-1.51, p = 0.001. A persistent NLR >3 during treatment with enzalutamide seems to have both prognostic and predictive value in CRPC patients.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
A multidisciplinary study was carried out on an Upper Pleistocene travertine mound (Montirone Hill; Abano Terme, south of Padova, Veneto, Italy) with the aim of developing a comprehensive ...understanding of the processes interacting in structurally controlled thermal springs and the consequent deposition of thermal limestones. The sedimentology, geochemistry, structural characteristics and hydrogeology of the mound, which is associated with the Euganean geothermal field and the related complex structural framework of the Schio‐Vicenza fault system, were investigated. A palaeo‐environmental model of the deposit has been reconstructed clarifying the connection between the travertine deposition and the regional structural setting. Calcium‐rich thermal waters rose from spring orifices (estimated temperature from 54°C to 61°C based on geochemical calculations) and produced a mound made of coalescent shield‐like bodies. The dominant lime‐mudstone facies resulted from the accumulation of lime mud at the bottom of shallow crater‐like basins located on top of stacked cones. Soft sediment deformations affecting the lime mud sediment were most probably produced by the recurrent uprising of gas bubbles. The overlying crystalline crusts were deposited on the flanks of the mound by waters overflowing from the vents with laminar flux. A deep hydrothermal circuit with a long period of water–rock interaction is supported by geochemical analyses. Furthermore, a local extensional regime, enhancing the migration of thermal fluids to the surface, is inferred based on the results of the structural analysis carried out on the fault/fracture mesh that affects the mound. These results corroborate the well‐established relation among travertine deposits, hydrothermal systems and fault systems, and substantiate the structurally controlled conceptual model of the Euganean hydrothermal system, suggesting that both the thermal and the fault systems were active at least since 34 ka.
Linear immunoglobulin A bullous dermatosis (LABD) is a rare, heterogeneous, autoimmune blistering disorder. Although the main characteristics of the disease seem to be well identified, international ...accepted diagnostic criteria are lacking. Several authors suggested their own criteria, but they are often not complete or even in contrast with clinical and immunopathological findings from the literature, while others are too selective. In this review, the current views and the problems with the definition of reliable diagnostic criteria for LABD will be discussed.
Stochastic multicomponent reactive transport modeling is a powerful approach to quantify the probability of non-exceedance (PNE) of arsenic (As) critical concentration thresholds in groundwater. The ...approach is applied to a well-characterized shallow alluvial aquifer near Venice, Italy. Here, As mobility depends primarily on rainfall-controlled redox-dependent precipitation-dissolution of iron hydroxides. A Monte-Carlo analysis based on a calibrated three-dimensional flow and transport model targeted the geochemical initial conditions as the main source of uncertainty of As concentrations in the studied aquifer. It was found that, during 115 simulated days, the fraction of the entire aquifer volume with As > 10 μgL−1 decreased on average from ~43% to ~39% and the average As concentration from ~32 μgL−1 to ~27 μgL−1. Meanwhile, PNE increased from 55% to 60% when 10 μgL−1 was set as target threshold, and from 71% to 78% for 50 μgL−1. The time dependence of As attenuation can be ascribed to the increase of oxidizing conditions during rainfall-dependent aquifer recharge, which causes As sorption on precipitating iron hydroxides. When computing the same statistics for the shallowest 6 m, As attenuation was even more evident. The volume fraction of aquifer with As > 10μgL−1 dropped from 40% to 28% and the average As concentration from 31 μgL−1 to 20 μgL−1, whereas PNE increased from 58% to 70% for As < 10 μgL−1 and from 71% to 86% for As < 50 μgL−1. Thus, the wells screen depth in the aquifer can be a critical aspect when estimating As risk, owing to the depth-dependent relative change in redox conditions during rainfall events.
Un settembre molto idrogeologico Ducci, Daniela; Fabbri, Paolo; Petitta, Marco ...
Acque Sotterranee,
10/2019, Letnik:
8, Številka:
3
Journal Article
Recenzirano
Odprti dostop
Nel settembre 2019 si sono avute molte occasioni di incontri e di riflessioni scientifiche per gli idrogeologi italiani. La rassegna degli eventi IAH o patrocinati da IAH che si sono svolti in questo ...periodo comincia con il congresso congiunto SIMP-SGI-SOGEI (Società Italiana di Mineralogia e Petrologia, Società Geologica Italiana e Società Geochimica Italiana) dal titolo “Il tempo del pianeta Terra e il tempo dell’uomo: Le geoscienze fra passato e futuro” che si è tenuto a Parma dal 16 al 19 settembre 2019 ....
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