Fornal and Grinstein recently proposed that the discrepancy between two different methods of neutron lifetime measurements, the beam and bottle methods, can be explained by a previously unobserved ...dark matter decay mode, n→X+γ. We perform a search for this decay mode over the allowed range of energies of the monoenergetic γ ray for X to be dark matter. A Compton-suppressed high-purity germanium detector is used to identify γ rays from neutron decay in a nickel-phosphorous-coated stainless-steel bottle. A combination of Monte Carlo and radioactive source calibrations is used to determine the absolute efficiency for detecting γ rays arising from the dark matter decay mode. We exclude the possibility of a sufficiently strong branch to explain the lifetime discrepancy with 97% confidence.
The ultracold neutron (UCN) source at Los Alamos National Laboratory (LANL), which uses solid deuterium as the UCN converter and is driven by accelerator spallation neutrons, has been successfully ...operated for over 10 years, providing UCN to various experiments, as the first production UCN source based on the superthermal process. It has recently undergone a major upgrade. This paper describes the design and performance of the upgraded LANL UCN source. Measurements of the cold neutron spectrum and UCN density are presented and compared to Monte Carlo predictions. The source is shown to perform as modeled. The UCN density measured at the exit of the biological shield was 184(32) UCN/cm3, a fourfold increase from the highest previously reported. The polarized UCN density stored in an external chamber was measured to be 39(7) UCN/cm3, which is sufficient to perform an experiment to search for the nonzero neutron electric dipole moment with a one-standard-deviation sensitivity of σ(dn)=3×10-27ecm.
The Nab experiment will measure the ratio of the weak axial-vector and vector coupling constants
λ
=
g
A
/
g
V
with precision
δ
λ
/
λ
∼ 3 × 10
− 4
and search for a Fierz term
b
F
at a level Δ
b
F
< ...10
− 3
. The Nab detection system uses thick, large area, segmented silicon detectors to very precisely determine the decay proton’s time of flight and the decay electron’s energy in coincidence and reconstruct the correlation between the antineutrino and electron momenta. Excellent understanding of systematic effects affecting timing and energy reconstruction using this detection system are required. To explore these effects, a series of ex situ studies have been undertaken, including a search for a Fierz term at a less sensitive level of Δ
b
F
< 10
− 2
in the beta decay of
45
Ca using the UCNA spectrometer.
Iridoviruses infect invertebrates (primarily insects and crustaceans) and ectothermic vertebrates (fish, amphibians, and reptiles). Identical, or nearly identical viruses, have been isolated from ...different animals within the same taxonomic class, indicating that infection by a given virus is not limited to a single species. Although inter-class infections have been documented following experimental infection with vertebrate iridoviruses, it is not clear whether such infections occur in nature. Here we report the isolation of apparently identical iridoviruses from wild sympatric fish (the threespine stickleback,
Gasterostelus aculeatus) and amphibians (the red-legged frog,
Rana aurora). Viruses isolated from sticklebacks (stickleback virus, SBV) and from a red-legged frog tadpole (tadpole virus 2, TV2) replicated in fathead minnow (FHM) cells and synthesized proteins which co-migrated with those of frog virus 3 (FV3). Following restriction endonuclease digestion of viral DNA with
Hind III and
Xba I, gel analysis showed that the profiles of SBV and TV2 were identical to each other and distinct from FV3. Using oligonucleotide primers specific for a highly conserved region of the iridovirus major capsid protein, an ∼500 nucleotide DNA fragment was amplified from SBV and TV2. Sequence analysis showed that within this 500 nucleotide region SBV and TV2 were identical to each other and to FV3. Taken together these results provide the first evidence that iridoviruses naturally infect animals belonging to different taxonomic classes, and strengthen the suggestion that fish may serve as a reservoir for amphibian viruses or vice versa.
Here, the precise value of the mean neutron lifetime, τn, plays an important role in nuclear and particle physics and cosmology. It is used to predict the ratio of protons to helium atoms in the ...primordial universe and to search for physics beyond the Standard Model of particle physics. We eliminated loss mechanisms present in previous trap experiments by levitating polarized ultracold neutrons above the surface of an asymmetric storage trap using a repulsive magnetic field gradient so that the stored neutrons do not interact with material trap walls. As a result of this approach and the use of an in situ neutron detector, the lifetime reported here 877.7 ± 0.7 (stat) +0.4/–0.2 (sys) seconds does not require corrections larger than the quoted uncertainties.
The chytrid fungus Batrachochytrium dendrobatidis was originally reported in wild frog populations in Panama and Australia, and from captive frogs in the U.S. National Zoological Park (Washington, ...DC). This recently described fungus affects the keratinized epidermis of amphibians and has been implicated as a causative factor in the declines of frog populations. We report here the presence of B. dendrobatidis in larval and recently metamorphosed mountain yellow-legged frogs (Rana muscosa) in or near the Sierra Nevada Mountains of California, an area where declines have been documented in all five species of native anurans. Forty-one percent (158 of 387) of larval R. muscosa examined in the field with a hand lens and 18% (14 of 79) of preserved larvae had abnormalities of the oral disc. Twenty-eight larvae were collected from 10 sites where tadpoles had been observed with missing or abnormally keratinized mouthparts, and 24 of these were examined for infection. Sixty-seven percent (16 of 24) of these tadpoles were infected with B. dendrobatidis. Batrachochytrium dendrobatidis was cultured from both tadpoles and recent metamorphs from one of these sites. Tadpoles with mouthpart abnormalities or confirmed chytrid fungus infections were collected at 23 sites spanning a distance of > 440 km and an elevational range from 1658–3550 m. Life-history traits of R. muscosa may make this species particularly susceptible to infection by Batrachochytrium. We recommend that biologists examine tadpoles for oral disc abnormalities as a preliminary indication of chytridiomycosis. Further, we believe that biologists should take precautions to prevent spreading this and other amphibian diseases from one site to another.
Human biology is tightly linked to proteins, yet most measurements do not precisely determine alternatively spliced sequences or posttranslational modifications. Here, we present the primary ...structures of ~30,000 unique proteoforms, nearly 10 times more than in previous studies, expressed from 1690 human genes across 21 cell types and plasma from human blood and bone marrow. The results, compiled in the Blood Proteoform Atlas (BPA), indicate that proteoforms better describe protein-level biology and are more specific indicators of differentiation than their corresponding proteins, which are more broadly expressed across cell types. We demonstrate the potential for clinical application, by interrogating the BPA in the context of liver transplantation and identifying cell and proteoform signatures that distinguish normal graft function from acute rejection and other causes of graft dysfunction.
In this paper we report studies of the Fermi potential and loss per bounce of ultracold neutron (UCN) on a deuterated scintillator (Eljen-299-02D). These UCN properties of the scintillator enables a ...wide variety of applications in fundamental neutron research.
Radiotracking studies of Townsend's big-eared bat (Corynorhinus townsendii) were conducted in grazed grassland and coastal forest (California bay, Douglas-fir, and redwood) at Point Reyes National ...Seashore in coastal central California. Radiotagged bats were used to determine the foraging patterns of both female and male bats and to locate alternate roost sites. The animals showed considerable loyalty to their primary roost sites even though the study was conducted after the nursery period had ended, when the bats would normally be dispersing for the season. Foraging patterns differed between male and female bats, with females traveling greater distances than males. Males consistently stayed close to the maternity colony both during day and night. Both sexes flew in the immediate vicinity of vegetation, both when foraging and when traveling from the roost to foraging areas. Foraging activity was concentrated primarily along the edges of riparian vegetation.
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