ABSTRACT We present the first spectroscopic confirmation of an ultramassive galaxy at redshift using data from Keck-NIRSPEC, VLT-X-shooter, and GTC-Osiris. We detect strong O iii and Ly emission, and ...weak O ii, C iv, and He ii, placing C1-23152 at a spectroscopic redshift of . The modeling of the emission-line-corrected spectral energy distribution (SED) results in a best-fit stellar mass of , a star formation rate of <7 yr−1, and negligible dust extinction. The stars appear to have formed in a short intense burst ∼300-500 Myr prior to the observation epoch, setting the formation redshift of this galaxy at z ∼ 4.1. From the analysis of the line ratios and widths and the observed flux at 24 m, we confirm the presence of a luminous hidden active galactic nucleus (AGN), with bolometric luminosity of erg s−1. Potential contamination of the observed SED from the AGN continuum is constrained, placing a lower limit on the stellar mass of . HST/WFC3 and ACS images are modeled, resulting in an effective radius of kpc in the band and a Sérsic index . This object may be a prototype of the progenitors of local most massive elliptical galaxies in the first 2 Gyr of cosmic history, having formed most of its stars at in a highly dissipative, intense, and short burst of star formation. C1-23152 is completing its transition to a post-starburst phase while hosting a powerful AGN, potentially responsible for the quenching of the star formation activity.
The enzymatic replacement therapy (ERT) availability for Gaucher disease (GD) has changed the landscape of the disease, several countries have screening programs. These actions have promoted the ...early diagnosis and avoided many complications in pediatric patients. In Spain ERT has been available since 1993 and 386 patients have been included in the Spanish Registry of Gaucher Disease (SpRGD). The aim of this study is to analyze the impact of ERT on the characteristics at time of diagnosis and initial complications in pediatric Gaucher disease patients.
To analyze the impact of ERT on the characteristics at time of diagnosis and initial complications in pediatric Gaucher disease patients.
A review of data in SpRGD from patients' diagnosed before 18 years old was performed. The cohort was split according the year of diagnosis (≤1994, cohort A; ≥1995, cohort B).
A total of 98 pediatric patients were included, GD1: 80, GD3: 18; mean age: 7.2 (0.17-16.5) years, 58 (59.2%) males and 40 (40.8%) females. Forty-five were diagnosed ≤ 1994 and 53 ≥ 1995. Genotype: N370S/N370S: 2 (2.0%), N370S/L444P: 27 (27.5%), N370S/other: 47 (48%), L444P/L444P: 7 (7.1%), L444P/D409H: 2 (2.0%), L444P/other: 3 (6.2%), other/other: 10 (10.2%). The mean age at diagnosis was earlier in patients diagnosed after 1995 (p < 0.001) and different between the subtypes, GD1: 8.2 (0.2-16.5) years and GD3: 2.8 (0.17-10.2) years (p < 0.001). There were more severe patients in the group diagnosed before 1994 (p = 0.045) carrying L444P (2), D409H (2), G377S (1), G195W (1) or the recombinant mutation. The patients' diagnosed ≤1994 showed worse cytopenias, higher chance of bone vascular complications at diagnosis and previous spleen removal. The patients started ERT at a median time after diagnosis of 5.2 years cohort A and 1.6 years cohort B (p < 0.001).
The early diagnosis of Gaucher disease in the era of ERT availability has permitted to reduce the incidence of severe and irreversible initial complication in pediatric patients, and this has permitted better development of these patients. This is the largest pediatric cohort from a national registry.
To the Editor, The advances made in surgical techniques followed by the best candidate selection process possible and optimal preparation of patients eligible for surgery have contributed to reducing ...early postoperative mortality in patients treated with the Fontan procedure.1 However, the balance provided by the Fontan procedure is precarious and can fail for multiple reasons that can be resolved through interventional catheterizations (IC).2-4 This study describes the experience of our center performing IC and focuses on the type of interventional procedures performed and predictors of these. We conducted a retrospective study of all patients < 18 years-old who underwent a Fontan procedure from January 2000 through December 2021 and were treated with IC due to suspected anatomical injury detected by echocardiography (annually) or magnetic resonance imaging (at 10 years and then every 3 years) or complications like protein-losing enteropathy, plastic bronchitis or hepatopathy. Since 2017, scheduled catheterizations are performed 10 years after the Fontan procedure. All patients gave their prior written informed consent, and the study was approved by the hospital ethics committee. Possible sex and gender variables have been considered in accordance with the SAGER guidelines. Descriptive statistics of the demographic, anatomical, hemodynamic, and surgical variables was used. Normally distributed variables were expressed as...
Abstract
We present eldar, a new method that exploits the potential of medium- and narrow-band filter surveys to securely identify active galactic nuclei (AGN) and determine their redshifts. Our ...methodology improves on traditional approaches by looking for AGN emission lines expected to be identified against the continuum, thanks to the width of the filters. To assess its performance, we apply eldar to the data of the ALHAMBRA (Advance Large Homogeneous Area Medium Band Redshift Astronomical) survey, which covered an effective area of 2.38 deg2 with 20 contiguous medium-band optical filters down to F814W ≃ 24.5. Using two different configurations of eldar in which we require the detection of at least two and three emission lines, respectively, we extract two catalogues of type-I AGN. The first is composed of 585 sources (79 per cent of them spectroscopically unknown) down to F814W = 22.5 at zphot > 1, which corresponds to a surface density of 209 deg−2. In the second, the 494 selected sources (83 per cent of them spectroscopically unknown) reach F814W = 23 at zphot > 1.5, for a corresponding number density of 176 deg−2. Then, using samples of spectroscopically known AGN in the ALHAMBRA fields, for the two catalogues we estimate a completeness of 73 per cent and 67 per cent, and a redshift precision of 1.01 per cent and 0.86 per cent (with outliers fractions of 8.1 per cent and 5.8 per cent). At z > 2, where our selection performs best, we reach 85 per cent and 77 per cent completeness and we find no contamination from galaxies.
The correlation function of the distribution of matter in the universe shows, at large scales, baryon acoustic oscillations, which were imprinted prior to recombination. This feature was first ...detected in the correlation function of the luminous red galaxies of the Sloan Digital Sky Survey (SDSS). Recently, the final release (DR7) of the SDSS has been made available, and the useful volume is about two times bigger than in the old sample. We present here, for the first time, the redshift-space correlation function of this sample at large scales together with that for one shallower, but denser volume-limited subsample drawn from the Two-Degree Field Redshift Survey. We test the reliability of the detection of the acoustic peak at about 100 h -1 Mpc and the behavior of the correlation function at larger scales by means of careful estimation of errors. We confirm the presence of the peak in the latest data although broader than in previous detections.
This paper aims to offer a free software program, LINCE PLUS, suitable for systematic observational studies in sports and health, conducted in natural contexts such as training, education or ...psychology. Using one or several videos simultaneously, different parameters such as behaviors, decision-making or strategies can be analyzed. The software includes several functionalities for studies that researchers need to utilize throughout the observational study process. Collaborative work can be accomplished by using simultaneous videos and multiple observers. The results of all research conducted by LINCE PLUS are offered inside the application in real time, enabling common calculations or including specific analysis with R language without the need for any other external tool. Moreover, LINCE PLUS shows the results of each study with interactive charts or, if needed, it exports the data to specific data analysis software programs (e.g., SAS, Excel, Theme, GSEQ 5, Hoisan). We include examples of sports and health studies that have been conducted with LINCE PLUS to show the suitability of this software program.
Measurements of clustering in large-scale imaging surveys that make use of photometric redshifts depend on the uncertainties in the redshift determination. We have used light-cone simulations to show ...how the deprojection method successfully recovers the real-space correlation function when applied to mock photometric redshift surveys. We study how the errors in the redshift determination affect the quality of the recovered two-point correlation function. Considering the expected errors associated with the planned photometric redshift surveys, we conclude that this method provides information on the clustering of matter useful for the estimation of cosmological parameters that depend on the large-scale distribution of galaxies.
NGC 1600: Cluster or Field Elliptical? Smith, Rodney M; Martínez, Vicent J; Fernández-Soto, Alberto ...
The Astrophysical journal,
05/2008, Letnik:
679, Številka:
1
Journal Article
Recenzirano
Odprti dostop
A study of the galaxy distribution in the field of the elliptical galaxy NGC 1600 has been undertaken. Although this galaxy is often classified as a member of a loose group, all the neighboring ...galaxies are much fainter and could be taken as satellites of NGC 1600. The number density profile of galaxies in the field of this galaxy shows a decline with radius, with evidence of a background at approximately 1.3 Mpc. The density and number density profile are consistent with that found for other isolated early-type galaxies. NGC 1600 appears as an extended source in X-rays, and the center of the X-ray emission seems not to coincide with the center of the galaxy. The velocity distribution of neighboring galaxies has been measured from optical spectroscopic observations and shows that the mean radial velocity is approximately 85 km s super(-1) less than that of NGC 1600, indicating that the center of mass could lie outside the galaxy. The velocity dispersion of the 'group' is estimated at image km s super(-1). The inferred mass of the system is therefore of the order of image, a value that corresponds to a large group. NGC 1600 therefore shares some similarities, but is not identical to, the 'fossil clusters' detected in X-ray surveys. Implications of this result for studies of isolated early-type galaxies are briefly discussed.
PDF
