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zadetkov: 571
1.
  • Diversity Explosion Diversity Explosion
    Frey, William H 07/2018
    eBook

    Greater racial diversity is good news for America's future Race is once again a contentious topic in America, as shown by the divisive rise of Donald Trump and the activism of groups like Black Lives ...
Celotno besedilo
Dostopno za: UPUK
2.
  • Intranasal delivery to the ... Intranasal delivery to the central nervous system: Mechanisms and experimental considerations
    Dhuria, Shyeilla V.; Hanson, Leah R.; Frey, William H. Journal of pharmaceutical sciences, April 2010, Letnik: 99, Številka: 4
    Journal Article
    Recenzirano

    The blood–brain barrier (BBB) limits the distribution of systemically administered therapeutics to the central nervous system (CNS), posing a significant challenge to drug development efforts to ...
Celotno besedilo
Dostopno za: BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
3.
  • Intranasal Insulin as a Tre... Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
    Freiherr, Jessica; Hallschmid, Manfred; Frey, William H. ... CNS drugs, 07/2013, Letnik: 27, Številka: 7
    Journal Article
    Recenzirano
    Odprti dostop

    Research in animals and humans has associated Alzheimer’s disease (AD) with decreased cerebrospinal fluid levels of insulin in combination with decreased insulin sensitivity (insulin resistance) in ...
Celotno besedilo
Dostopno za: EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ

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4.
  • Intranasal Treatment of Cen... Intranasal Treatment of Central Nervous System Dysfunction in Humans
    Chapman, Colin D.; Frey, William H.; Craft, Suzanne ... Pharmaceutical research, 10/2013, Letnik: 30, Številka: 10
    Journal Article
    Recenzirano
    Odprti dostop

    ABSTRACT One of the most challenging problems facing modern medicine is how to deliver a given drug to a specific target at the exclusion of other regions. For example, a variety of compounds have ...
Celotno besedilo
Dostopno za: EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ

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5.
  • Cannabinoid-Mediated Modula... Cannabinoid-Mediated Modulation of Neuropathic Pain and Microglial Accumulation in a Model of Murine Type I Diabetic Peripheral Neuropathic Pain
    Toth, Cory C; Jedrzejewski, Nicole M; Ellis, Connie L ... Molecular pain, 03/2010, Letnik: 6, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Background: Despite the frequency of diabetes mellitus and its relationship to diabetic peripheral neuropathy (DPN) and neuropathic pain (NeP), our understanding of underlying mechanisms leading to ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK

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6.
  • Mechanisms of Intranasal De... Mechanisms of Intranasal Deferoxamine in Neurodegenerative and Neurovascular Disease
    Kosyakovsky, Jacob; Fine, Jared M; Frey, 2nd, William H ... Pharmaceuticals, 01/2021, Letnik: 14, Številka: 2
    Journal Article, Book Review
    Recenzirano
    Odprti dostop

    Identifying disease-modifying therapies for neurological diseases remains one of the greatest gaps in modern medicine. Herein, we present the rationale for intranasal (IN) delivery of deferoxamine ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK

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7.
  • Brain Insulin Signaling and... Brain Insulin Signaling and Alzheimer's Disease: Current Evidence and Future Directions
    Schiöth, Helgi B.; Craft, Suzanne; Brooks, Samantha J. ... Molecular neurobiology, 08/2012, Letnik: 46, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    Insulin receptors in the brain are found in high densities in the hippocampus, a region that is fundamentally involved in the acquisition, consolidation, and recollection of new information. Using ...
Celotno besedilo
Dostopno za: EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ

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8.
  • Intranasal insulin treatmen... Intranasal insulin treatment of an experimental model of moderate traumatic brain injury
    Brabazon, Fiona; Wilson, Colin M; Jaiswal, Shalini ... Journal of cerebral blood flow and metabolism, 09/2017, Letnik: 37, Številka: 9
    Journal Article
    Recenzirano
    Odprti dostop

    Traumatic brain injury (TBI) results in learning and memory dysfunction. Cognitive deficits result from cellular and metabolic dysfunction after injury, including decreased cerebral glucose uptake ...
Celotno besedilo
Dostopno za: NUK, OILJ, SAZU, UKNU, UL, UM, UPUK

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9.
  • Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease
    Danielyan, Lusine; Schäfer, Richard; von Ameln-Mayerhofer, Andreas ... Rejuvenation research 14, Številka: 1
    Journal Article
    Recenzirano

    Safe and effective cell delivery remains one of the main challenges in cell-based therapy of neurodegenerative disorders. Graft survival, sufficient enrichment of therapeutic cells in the brain, and ...
Preverite dostopnost
10.
  • Intranasal insulin as a the... Intranasal insulin as a therapeutic option in the treatment of cognitive impairments
    Benedict, Christian; Frey, William H.; Schiöth, Helgi B. ... Experimental gerontology, 02/2011, Letnik: 46, Številka: 2
    Journal Article
    Recenzirano

    The brain is a major target of circulating insulin. Enhancing central nervous insulin action has been shown to improve memory functions in animals as well as in humans, benefitting in particular ...
Celotno besedilo
Dostopno za: GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
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zadetkov: 571

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