ABSTRACT We report a spin-orbit misalignment for the hot-Jupiter HATS-14b, measuring a projected orbital obliquity of HATS-14b orbits a high metallicity, 5400 K G dwarf in a relatively short period ...orbit of 2.8 days. This obliquity was measured via the Rossiter-McLaughlin effect, obtained with observations from Keck-HIRES. The velocities were extracted using a novel technique, optimized for low signal-to-noise spectra, achieving a high precision of point-to-point scatter. However, we caution that our uncertainties may be underestimated. Due to the low rotational velocity of the star, the detection significance is dependent on the prior that is imposed in our modeling. Based on trends observed in the sample of hot Jupiters with obliquity measurements, it has been suggested that these planets modify the spin axes of their host stars, with an efficiency that depends on the stellar type and orbital period of the system. In this framework, short-period planets around stars with surface convective envelopes, like HATS-14b, are expected to have orbits that are aligned with the spin axes of their host stars. HATS-14b, however, is a significant outlier from this trend, challenging the effectiveness of the tidal realignment mechanism.
Las Cumbres Observatory Global Telescope Network Brown, T. M.; Baliber, N.; Bianco, F. B. ...
Publications of the Astronomical Society of the Pacific,
09/2013, Letnik:
125, Številka:
931
Journal Article
Recenzirano
Odprti dostop
Las Cumbres Observatory Global Telescope (LCOGT) is a young organization dedicated to time-domain observations at optical and (potentially) near-IR wavelengths. To this end, LCOGT is constructing a ...worldwide network of telescopes, including the two 2 m Faulkes telescopes, as many as 17 × 1 m telescopes, and as many as 23 × 40 cm telescopes. These telescopes initially will be outfitted for imaging and (excepting the 40 cm telescopes) spectroscopy at wavelengths between the atmospheric UV cutoff and the roughly 1-μm limit of silicon detectors. Since the first of LCOGT's 1 m telescopes are now being deployed, we lay out here LCOGT's scientific goals and the requirements that these goals place on network architecture and performance, we summarize the network's present and projected level of development, and we describe our expected schedule for completing it. In the bulk of the paper, we describe in detail the technical approaches that we have adopted to attain desired performance. In particular, we discuss our choices for the number and location of network sites, for the number and sizes of telescopes, for the specifications of the first generation of instruments, for the software that will schedule and control the network's telescopes and reduce and archive its data, and for the structure of the scientific and educational programs for which the network will provide observations.
ABSTRACT Luhman-16 (WISE J1049-5319) was recently discovered to be a nearby (∼2 pc) brown dwarf binary that exhibits a high degree of photometric variability (Δm ∼ 0.1 mag). This is thought to be due ...to the evolution of "cloud" features on the photosphere, but Luhman-16 has been found to show unusually rapid changes, possibly resulting from fast-evolving "weather." This target is of particular interest because it consists of a co-evolutionary pair of brown dwarfs spanning the transition between L and T spectral types (L7.5 and T0.5), which are expected to be associated with changes in cloud surface coverage. Being comparatively bright (I ∼ 15.5 mag), the target is well suited for observation with the new Las Cumbres Observatory Global Telescope Network (LCOGT) of 1 m telescopes. We present long-time baseline photometric observations from two of LCOGT's southern hemisphere sites, which were used in tandem to monitor Luhman-16 for up to 13.25 hr at a time (more than twice the rotation period), for a total of 41.2 days in the SDSS-i′ and Pan-STARRS-Z filters. We use this data set to characterize the changing rotational modulation, which may be explained by the evolution of cloud features at varying latitudes on the surfaces of the two brown dwarfs.
The amount of ultraviolet irradiation and ablation experienced by a planet depends strongly on the temperature of its host star. Of the thousands of extrasolar planets now known, only six have been ...found that transit hot, A-type stars (with temperatures of 7,300-10,000 kelvin), and no planets are known to transit the even hotter B-type stars. For example, WASP-33 is an A-type star with a temperature of about 7,430 kelvin, which hosts the hottest known transiting planet, WASP-33b (ref. 1); the planet is itself as hot as a red dwarf star of type M (ref. 2). WASP-33b displays a large heat differential between its dayside and nightside, and is highly inflated-traits that have been linked to high insolation. However, even at the temperature of its dayside, its atmosphere probably resembles the molecule-dominated atmospheres of other planets and, given the level of ultraviolet irradiation it experiences, its atmosphere is unlikely to be substantially ablated over the lifetime of its star. Here we report observations of the bright star HD 195689 (also known as KELT-9), which reveal a close-in (orbital period of about 1.48 days) transiting giant planet, KELT-9b. At approximately 10,170 kelvin, the host star is at the dividing line between stars of type A and B, and we measure the dayside temperature of KELT-9b to be about 4,600 kelvin. This is as hot as stars of stellar type K4 (ref. 5). The molecules in K stars are entirely dissociated, and so the primary sources of opacity in the dayside atmosphere of KELT-9b are probably atomic metals. Furthermore, KELT-9b receives 700 times more extreme-ultraviolet radiation (that is, with wavelengths shorter than 91.2 nanometres) than WASP-33b, leading to a predicted range of mass-loss rates that could leave the planet largely stripped of its envelope during the main-sequence lifetime of the host star.
Abstract Marine ecosystem-based management (EBM) is recognized as the best practice for managing multiple ocean-use sectors, explicitly addressing tradeoffs among them. However, implementation is ...perceived as challenging and often slow. A poll of over 150 international EBM experts revealed progress, challenges, and solutions in EBM implementation worldwide. Subsequent follow-up discussions with over 40 of these experts identified remaining impediments to further implementation of EBM: governance; stakeholder engagement; support; uncertainty about and understanding of EBM; technology and data; communication and marketing. EBM is often portrayed as too complex or too challenging to be fully implemented, but we report that identifiable and achievable solutions exist (e.g., political will, persistence, capacity building, changing incentives, and strategic marketing of EBM), for most of these challenges and some solutions can solve many impediments simultaneously. Furthermore, we are advancing in key components of EBM by practitioners who may not necessarily realize they are doing so under different paradigms. These findings indicate substantial progress on EBM, more than previously reported.
It is important to explore the diversity of characteristics of low-mass, low-density planets to understand the nature and evolution of this class of planets. We present a homogeneous analysis of 12 ...new and 9 previously published broad-band photometric observations of the Uranus-sized extrasolar planet GJ 3470b, which belongs to the growing sample of sub-Jovian bodies orbiting M dwarfs. The consistency of our analysis explains some of the discrepancies between previously published results and provides updated constraints on the planetary parameters. Our data are also consistent with previous transit observations of this system. The physical properties of the transiting system can only be constrained as well as the host star is characterized, so we provide new spectroscopic measurements of GJ 3470 from 0.33 to 2.42 μm to aid our analysis. We find R
* = 0.48 ± 0.04 R⊙, M
* = 0.51 ± 0.06 M⊙, and T
eff = 3652 ± 50K for GJ 3470, along with a rotation period of 20.70 ± 0.15 d and an R-band amplitude of 0.01 mag, which is small enough that current transit measurements should not be strongly affected by stellar variability. However, to report definitively whether stellar activity has a significant effect on the light curves, this requires future multiwavelength, multi-epoch studies of GJ 3470. We also present the most precise orbital ephemeris for this system: T
o
= 2455983.70472 ± 0.00021BJDTDB, P = 3.336 6487
$^{+0.000\,0043}_{-0.000\,0033}$
d, and we see no evidence for transit timing variations greater than 1 min. Our reported planet to star radius ratio is 0.076 42 ± 0.000 37. The physical parameters of this planet are R
p = 3.88 ± 0.32 R⊕ and M
p = 13.73 ± 1.61 M⊕. Because of our revised stellar parameters, the planetary radius we present is smaller than previously reported values. We also perform a second analysis of the transmission spectrum of the entire ensemble of transit observations to date, supporting the existence of an H2-dominated atmosphere exhibiting a strong Rayleigh scattering slope.
A Catalog of Reference Genomes from the Human Microbiome Nelson, Karen E; Weinstock, George M; Highlander, Sarah K ...
Science (American Association for the Advancement of Science),
05/2010, Letnik:
328, Številka:
5981
Journal Article
Recenzirano
Odprti dostop
The human microbiome refers to the community of microorganisms, including prokaryotes, viruses, and microbial eukaryotes, that populate the human body. The National Institutes of Health launched an ...initiative that focuses on describing the diversity of microbial species that are associated with health and disease. The first phase of this initiative includes the sequencing of hundreds of microbial reference genomes, coupled to metagenomic sequencing from multiple body sites. Here we present results from an initial reference genome sequencing of 178 microbial genomes. From 547,968 predicted polypeptides that correspond to the gene complement of these strains, previously unidentified ("novel") polypeptides that had both unmasked sequence length greater than 100 amino acids and no BLASTP match to any nonreference entry in the nonredundant subset were defined. This analysis resulted in a set of 30,867 polypeptides, of which 29,987 (̃97%) were unique. In addition, this set of microbial genomes allows for ̃40% of random sequences from the microbiome of the gastrointestinal tract to be associated with organisms based on the match criteria used. Insights into pan-genome analysis suggest that we are still far from saturating microbial species genetic data sets. In addition, the associated metrics and standards used by our group for quality assurance are presented.
We report the discovery of a multiplanetary system transiting the M0 V dwarf HD 260655 (GJ 239, TOI-4599). The system consists of at least two transiting planets, namely HD 260655 b, with a period of ...2.77 d, a radius of
R
b
= 1.240 ± 0.023
R
⊕
, a mass of
M
b
= 2.14 ± 0.34
M
⊕
, and a bulk density of
ρ
b
= 6.2 ± 1.0 g cm
−3
, and HD 260655 c, with a period of 5.71 d, a radius of ${R_c} = 1.533_{ - 0.046}^{ + 0.051}{R_ \oplus }$, a mass of
M
c
= 3.09 ± 0.48
M
⊕
, and a bulk density of ${\rho _c} = 4.7_{ - 0.8}^{ + 0.9}{\rm{g}}$ g cm
−3
. The planets have been detected in transit by the Transiting Exoplanet Survey Satellite (TESS) mission and confirmed independently with archival and new precise radial velocities obtained with the HIRES and CARMENES instruments since 1998 and 2016, respectively. At a distance of 10 pc, HD 260655 has become the fourth closest known multitransiting planet system after HD 219134, LTT 1445 A, and AU Mic. Due to the apparent brightness of the host star (
J
= 6.7 mag), both planets are among the most suitable rocky worlds known today for atmospheric studies with the
James Webb
Space Telescope, both in transmission and emission.
Aromatase and COX-2 expression in human breast cancers Brodie, A.M.H; Lu, Q; Long, B.J ...
Journal of steroid biochemistry and molecular biology,
12/2001, Letnik:
79, Številka:
1
Journal Article, Conference Proceeding
Recenzirano
We have investigated aromatase and the inducible cyclooxygenase COX-2 expression using immunocytochemistry in tumors of a series of patients with advanced breast cancer treated with aromatase ...inhibitors. Aromatase was expressed in 58/102 breast cancers. This is similar to the percentage previously reported for aromatase activity. Interestingly, aromatase was expressed in a variety of cell types, including tumor, stromal, adipose, and endothelial cells. Since prostaglandin E
2 is known to regulate aromatase gene expression and is the product of COX-2, an enzyme frequently overexpressed in tumors, immunocytochemistry was performed on the tissue sections using a polyclonal antibody to COX-2. Aromatase was strongly correlated (
P<0.001) with COX-2 expression. These results suggest that PGE
2 produced by COX-2 in the tumor may be important in stimulating estrogen synthesis in the tumor and surrounding tissue. No correlation was observed between aromatase or COX-2 expression and the response of the patients to aromatase inhibitor treatment. However, only 13 patients responded. Nine of these patients were aromatase positive. Although similar to responses in other studies, this low response rate to second line treatment suggests that tumors of most patients were no longer sensitive to the effects of estrogen. Recent clinical studies suggest that greater responses occur when aromatase inhibitors are used as first line treatment. In the intratumoral aromatase mouse model, expression of aromatase in tumors is highly correlated with increased tumor growth. First line treatment with letrozole was effective in all animals treated and was more effective than tamoxifen in suppressing tumor growth. Letrozole was also effective in tumors failing to respond to tamoxifen, consistent with clinical findings. In addition, the duration of response was significantly longer with the aromatase inhibitor than with tamoxifen, suggesting that aromatase inhibitors may offer better control of tumor growth than this antiestrogen.
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