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zadetkov: 901
1.
  • Gene copy-number polymorphi... Gene copy-number polymorphism caused by retrotransposition in humans
    Schrider, Daniel R; Navarro, Fabio C P; Galante, Pedro A F ... PLOS genetics, 01/2013, Letnik: 9, Številka: 1
    Journal Article
    Recenzirano
    Odprti dostop

    The era of whole-genome sequencing has revealed that gene copy-number changes caused by duplication and deletion events have important evolutionary, functional, and phenotypic consequences. Recent ...
Celotno besedilo
Dostopno za: DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK

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2.
  • Monoallelic deleterious MUT... Monoallelic deleterious MUTYH germline variants as a driver for tumorigenesis
    Barreiro, Rodrigo Araujo Sequeira; Sabbaga, Jorge; Rossi, Benedito M ... The Journal of pathology, February 2022, 2022-02-00, 20220201, Letnik: 256, Številka: 2
    Journal Article
    Recenzirano

    MUTYH encodes a glycosylase involved in the base excision repair of DNA. Biallelic pathogenic germline variants in MUTYH cause an autosomal recessive condition known as MUTYH‐associated adenomatous ...
Celotno besedilo
Dostopno za: BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK
3.
  • Host gene constraints and g... Host gene constraints and genomic context impact the expression and evolution of human microRNAs
    França, Gustavo S; Vibranovski, Maria D; Galante, Pedro A F Nature communications, 04/2016, Letnik: 7, Številka: 1
    Journal Article
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    Increasing evidence has shown that recent miRNAs tend to emerge within coding genes. Here we conjecture that human miRNA evolution is tightly influenced by the genomic context, especially by host ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK

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4.
  • Impact of the thyroid hormo... Impact of the thyroid hormone T3 and its nuclear receptor TRα1 on colon cancer stem cell phenotypes and response to chemotherapies
    Giolito, Maria Virginia; Bodoirat, Serguei; La Rosa, Theo ... Cell death & disease, 2024-May-01, 2024-05-01, 20240501, Letnik: 15, Številka: 5
    Journal Article
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    Colorectal cancers (CRCs) are highly heterogeneous and show a hierarchical organization, with cancer stem cells (CSCs) responsible for tumor development, maintenance, and drug resistance. Our ...
Celotno besedilo
Dostopno za: NUK, UL, UM, UPUK
5.
  • Patient-derived conditional... Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity
    Correa, Bruna R S; Hu, Joanna; Penalva, Luiz O F ... Scientific reports, 03/2018, Letnik: 8, Številka: 1
    Journal Article
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    Preclinical in vitro models provide an essential tool to study cancer cell biology as well as aid in translational research, including drug target identification and drug discovery efforts. For any ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK

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6.
  • Severe Acute Respiratory Sy... Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern: A Perspective for Emerging More Transmissible and Vaccine-Resistant Strains
    de Souza, Anacleto Silva; de Freitas Amorim, Vitor Martins; Guardia, Gabriela D A ... Viruses, 04/2022, Letnik: 14, Številka: 4
    Journal Article
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    Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC) are constantly threatening global public health. With no end date, the pandemic persists with the ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
7.
  • The Clinical and Molecular ... The Clinical and Molecular Profile of Lung Cancer Patients Harboring the TP53 R337H Germline Variant in a Brazilian Cancer Center: The Possible Mechanism of Carcinogenesis
    Lopes, Carlos D. H.; Antonacio, Fernanda F.; Moraes, Priscila M. G. ... International journal of molecular sciences, 10/2023, Letnik: 24, Številka: 20
    Journal Article
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    In southern and southeastern Brazil, the TP53 founder variant c.1010G>A (R337H) has been previously documented with a prevalence of 0.3% within the general population and linked to a heightened ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
8.
  • Alternative polyadenylation... Alternative polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR
    Hinske, Ludwig Christian; Galante, Pedro A F; Limbeck, Elisabeth ... PloS one, 03/2015, Letnik: 10, Številka: 3
    Journal Article
    Recenzirano
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    About half of the known miRNA genes are located within protein-coding host genes, and are thus subject to co-transcription. Accumulating data indicate that this coupling may be an intrinsic mechanism ...
Celotno besedilo
Dostopno za: DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK

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9.
  • A potential role for intrag... A potential role for intragenic miRNAs on their hosts' interactome
    Hinske, Ludwig Christian G; Galante, Pedro A F; Kuo, Winston P ... BMC genomics, 10/2010, Letnik: 11, Številka: 1
    Journal Article
    Recenzirano
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    miRNAs are small, non-coding RNA molecules that mainly act as negative regulators of target gene messages. Due to their regulatory functions, they have lately been implicated in several diseases, ...
Celotno besedilo
Dostopno za: DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK

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10.
  • Acute Myeloid Leukemia Expr... Acute Myeloid Leukemia Expresses a Specific Group of Olfactory Receptors
    Guardia, Gabriela D A; Naressi, Rafaella G; Buzzato, Vanessa C ... Cancers, 06/2023, Letnik: 15, Številka: 12
    Journal Article
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    Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with a 5-year overall survival rate of approximately 30%. Despite recent advances in therapeutic options, relapse ...
Celotno besedilo
Dostopno za: IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
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zadetkov: 901

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