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Provider: - Institution: - Data provided by Europeana Collections- Avec mode texte- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal ...Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Avec mode texte- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal ...Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Avec mode texte- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal ...Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Avec mode texte- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal ...Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
High‐throughput DNA analyses in cancers allow the detection of molecular abnormalities that can guide patients' treatment. The collection of a tumour DNA is mainly performed on a biopsy, an invasive ...procedure for the patients. Another less invasive method consists in using a fine needle. We showed that fine‐needle biopsies are as suitable as a classical biopsy for DNA analysis.
High‐throughput molecular profiling of solid tumours using core needle biopsies (CNB) allows the identification of actionable molecular alterations, with around 70% success rate. Although several studies have demonstrated the utility of small biopsy specimens for molecular testing, there remains debate as to the sensitivity of the less invasive fine‐needle aspiration (FNA) compared to CNB to detect molecular alterations. We aimed to prospectively evaluate the potential of FNA to detect such alterations in various tumour types as compared to CNB in cancer patients included in the SHIVA02 trial. An in‐house amplicon‐based targeted sequencing panel (Illumina TSCA 99.3 kb panel covering 87 genes) was used to identify pathogenic variants and gene copy number variations (CNV) in concomitant CNB and FNA samples obtained from 61 patients enrolled in the SHIVA02 trial (NCT03084757). The main tumour types analysed were breast (38%), colon (15%), pancreas (11%), followed by cervix and stomach (7% each). We report 123 molecular alterations (85 variants, 23 amplifications and 15 homozygous deletions) among which 98 (80%) were concordant between CNB and FNA. The remaining discordances were mainly related to deletions status, yet undetected alterations were not exclusively specific to FNA. Comparative analysis of molecular alterations in CNB and FNA showed high concordance in terms of variants as well as CNVs identified. We conclude FNA could therefore be used in routine diagnostics workflow and clinical trials for tumour molecular profiling with the advantages of being minimally invasive and preserve tissue material needed for diagnostic, prognostic or theranostic purposes.
Recently, intriguing physical properties have been unraveled in anisotropic semiconductors, in which the in-plane electronic band structure anisotropy often originates from the low crystallographic ...symmetry. The atomic chain is the ultimate limit in material downscaling for electronics, a frontier for establishing an entirely new field of onedimensional quantum materials. Electronic and structural properties of chain-like InTe are essential for better understanding of device applications such as thermoelectrics. Here, we use scanning tunneling microscopy/spectroscopy (STM/STS) measurements and density functional theory (DFT) calculations to directly image the in-plane structural anisotropy in tetragonal Indium Telluride (InTe). As results, we report the direct observation of one-dimensional In$^{1+}$ chains in InTe. We demonstrate that InTe exhibits a band gap of about 0.40 $\pm$ 0.02 eV located at the $M$ point of the Brillouin zone. Additionally, line defects are observed in our sample, were attributed to In$^{1+}$ chain vacancy along the c-axis, a general feature in many other TlSe-like compounds. Our STS and DFT results prove that the presence of In$^{1+}$ induces localized gap state, located near the valence band maximum (VBM). This acceptor state is responsible for the high intrinsic p-type doping of InTe that we also confirm using angle-resolved photoemission spectroscopy.
Oestrus ovis sinusitis in a dog Azoulay, Florian; Girard, Nicolas; Gatel, Laure ...
Veterinary record case reports,
12/2023, Letnik:
11, Številka:
4
Journal Article
Recenzirano
Abstract
A 2‐year‐old, female Cane Corso was presented for chronic epistaxis, reverse sneezing and purulent nasal discharge. Clinical examination was unremarkable. Bloodwork revealed a mild anaemia. ...Computed tomography of the nasal cavity was consistent with right frontal sinusitis with suspected foreign bodies. Surgical approach of the right sinus by frontal osteotomy allowed to perform an endoscopically guided extraction of a 15‐mm white ringed worm and multiple black worm‐like structures. The evaluation by an EVPC diplomate confirmed an
Oestrus ovis
infestation. After endoscopic lavage of the frontal sinus, the dog went home with an ivermectin‐based treatment. It was presented 7 months later for a recurrence of the clinical signs. Tomography and surgical approach to the right frontal sinus revealed persistent presence of the
O. ovis
infestation. After surgical removal of the parasite and oral isoxazoline treatment, the dog had no signs of clinical recurrence. Follow‐up computed tomography scan confirmed complete resolution of the sinusitis.
The objective of this work is to compare the ability of three spectroscopy techniques: molecular fluorescence, near-infrared (NIR), and mid-infrared with attenuated total reflectance (MIR-ATR) ...spectroscopy to predict the concentrations of 8 carotenoids, 6 vitamins and 22 fatty acids (FA) in cow's milk. A dataset was built through the analysis of 242 frozen milk samples from different experiments. The milk compounds were analysed using reference methods and by NIR, MIR-ATR, and fluorescence to establish different predictive models. NIR spectroscopy allowed for better prediction of cis9-β-carotene, β-cryptoxanthin and the sum of carotenoids than the other techniques, with a coefficient of cross-validation in calibration (R
CV) > 0.60 and a coefficient of determination in validation (R
V) > 0.50. Their standard errors of prediction (SEP) were equal to 0.01, except for the sum of carotenoids (SEP = 0.15). However, MIR-ATR and fluorescence seem usable for the prediction of lutein and all-trans-β-carotene, respectively. These three spectroscopy methods did not allow us to predict (R
CV < 0.30) vitamin contents except, for vitamin A (the best R²CV = 0.65 with NIR and SEP = 0.15) and α-tocopherol (the best R²CV = 0.56 with MIR-ATR and SEP = 0.41), but all R²V were <0.30. NIR spectroscopy yielded the best prediction of the selected milk FA.
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