Missence mutation in codon 717 of the amyloid precursor protein (APP) gene that codes for the precursor to the beta-protein found in the amyloid deposits of Alzheimer disease was recently shown to be ...segregated with this disease in some kindreds. The following study aimed to determine the frequency of the codon 717 mutation in familial and "sporadic" cases of dementia of the Alzheimer type has been performed in Russian patients. 62 patients with senile dementia and the Alzheimer disease with early and late onset and 43 normal controls were tested for this mutation. None of them were positive. Thus this mutation is considered to be rare in studied population though in some cases it may be the cause of the disease.
Aqueous petroleum-oxidizing Arthrobacter Koronelli, T V; Golimbet, V E; Ushakova, N A ...
Mikrobiologija (Moskva. 1932),
1978 May-Jun, Letnik:
47, Številka:
3
Journal Article
Recenzirano
Water petroleum oxidizing bacteria of Arthrobacter ceroformans as well as their lipid composition are described. On a medium containing hexadecane, all the strains produce wax in large amounts (upto ...70% of total free lipids) consisting by 95% of cetyl palmitate. Fatty acids are represented mainly by palmitic acid but comprise also unsaturated C16:1 and C18:1 acids. Mycolic acids have not been detected. The significance of lipid composition for the identification of arthrobacteria is discussed.
