ABREVIATURAS Lorenzo Morillas Cueva; Ignacio F. Benítez Ortúzar; Miguel Ángel Cano Paños ...
Respuestas jurídicas al fraude en el deporte,
10/2017
Book Chapter
Front Matter Lorenzo Morillas Cueva; Ignacio F. Benítez Ortúzar; Miguel Ángel Cano Paños ...
Respuestas jurídicas al fraude en el deporte,
10/2017
Book Chapter
Resultados a manera de conclusiones Lorenzo Morillas Cueva; Ignacio F. Benítez Ortúzar; Miguel Ángel Cano Paños ...
Respuestas jurídicas al fraude en el deporte,
10/2017
Book Chapter
1ª.1¹. Es frecuente encontrar en las múltiples declaraciones internacionales sobre el deporte, la alusión a la parte más negativa de aquel, la corrupción, el fraude y la manipulación de resultados, y ...ello, como fenómeno permanente y a pesar de los esfuerzos que tanto instituciones públicas de carácter transnacional como interno están desarrollando con tenacidad y compromiso en la búsqueda de soluciones que neutralicen semejante tendencia. En tal sentido, hay que resaltar, como muestra, medidas tales como las de conseguir legislaciones más estrictas y a la vez proporcionadas, compartir información entre países, intensificar la cooperación judicial al respecto, promover la educación
Back Matter Lorenzo Morillas Cueva; Ignacio F. Benítez Ortúzar; Miguel Ángel Cano Paños ...
Respuestas jurídicas al fraude en el deporte,
10/2017
Book Chapter
Modern railway transportation systems need a reliable communication infrastructure providing very high data rates and low latencies for applications such as communications-based train control (CBTC) ...or video surveillance. In this paper, the suitability of the Long Term Evolution (LTE) standard for subway environments is evaluated using a propagation model based on real channel measurements. An LTE deployment with several subway stations is simulated using the ns-3 discrete-event network simulator to evaluate both the system performance and the fulfillment of the quality of service (QoS) requirements of representative services such as CBTC, closed-circuit television (CCTV), voice over IP (VoIP) and file transfer. Several parameters and procedures of the LTE system are adapted to the subway environment: the LTE network is configured using a QoS-aware scheduler, hence critical services are prioritized; the handover procedure is tuned to avoid ping-pong effects; and inter-cell interference coordination techniques are also applied.
The Canarias InfraRed Camera Experiment (CIRCE) is a near-infrared (1-2.5 micron) imager, polarimeter and low-resolution spectrograph operating as a visitor instrument for the Gran Telescopio ...Canarias 10.4-meter telescope. It was designed and built largely by graduate students and postdocs, with help from the UF astronomy engineering group, and is funded by the University of Florida and the U.S. National Science Foundation. CIRCE is intended to help fill the gap in near-infrared capabilities prior to the arrival of EMIR to the GTC, and will also provide the following scientific capabilities to compliment EMIR after its arrival: high-resolution imaging, narrowband imaging, high-time-resolution photometry, imaging polarimetry, low resolution spectroscopy. In this paper, we review the design, fabrication, integration, lab testing, and on-sky performance results for CIRCE. These include a novel approach to the opto-mechanical design, fabrication, and alignment.
Background: Prolonged mitotic arrest in response to anti-cancer chemotherapeutics, such as DNA-damaging agents, induces apoptosis, mitotic catastrophe, and senescence. Disruptions in mitotic ...checkpoints contribute resistance to DNA-damaging agents in cancer. MAD2 has been associated with checkpoint failure and chemotherapy response. In this study, a novel splice variant of MAD2, designated MAD2γ, was identified, and its association with the DNA damage response was investigated.
Methods: Endogenous expression of MAD2γ and full-length MAD2 (MAD2α) was measured using RT-PCR in cancer cell lines, normal foreskin fibroblasts, and tumor samples collected from patients with testicular germ cell tumors (TGCTs). A plasmid expressing MAD2γ was transfected into HCT116 cells, and its intracellular localization and checkpoint function were evaluated according to immunofluorescence and mitotic index.
Results: MAD2γ was expressed in several cancer cell lines and non-cancerous fibroblasts. Ectopically expressed MAD2γ localized to the nucleus and reduced the mitotic index, suggesting checkpoint impairment. In patients with TGCTs, the overexpression of endogenous MAD2γ, but not MAD2α, was associated with resistance to cisplatin-based chemotherapy. Likewise, cisplatin induced the overexpression of endogenous MAD2γ, but not MAD2α, in HCT116 cells.
Conclusions: Overexpression of MAD2γ may play a role in checkpoint disruption and is associated with resistance to cisplatin-based chemotherapy in TGCTs.
Provider: - Institution: Gredos. Repositorio Documental de la Universidad de Salamanca - Data provided by Europeana Collections- Memoria ID-0269. Ayudas de la Universidad de Salamanca para la ...innovación docente, curso 2014-2015.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: Gredos. Repositorio Documental de la Universidad de Salamanca - Data provided by Europeana Collections- Memoria ID-0121. Ayudas de la Universidad de Salamanca para la ...innovación docente, curso 2015-2016.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Apps y economía II. Memoria final Domínguez Pérez, José Ángel; Miguel Hidalgo, Alberto de; Rodríguez Vicente, Santiago ...
2016
Web Resource
Provider: - Institution: Gredos. Repositorio Documental de la Universidad de Salamanca - Data provided by Europeana Collections- Memoria ID-0182. Ayudas de la Universidad de Salamanca para la ...innovación docente, curso 2015-2016.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
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