To clarify risk factors for dementia associated with cerebral infarction.
Case-control study.
The study was conducted in a hospital setting.
The subjects were consecutive patients with acute stroke ...with multiple cerebral infarctions who were admitted to the hospital between November 1, 1987, and December 1, 1990. They were predominantly elderly African Americans. Index cases met criteria of the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, for multi-infarct dementia, whereas control subjects were patients with multiple infarcts who did not have dementia. There were 61 multi-infarct disease index cases and 86 controls without cognitive impairment.
Demographic and cardiovascular disease risk factor variables.
Index cases were older (mean +/- SD age, 75.5 +/- 9.7 vs 69.6 +/- 9.1 years), were less well educated (odds ratio, 4.37; confidence interval, 2.12 to 9.04), had lower annual incomes (odds ratio, 8.82; confidence interval, 2.38 to 32.70), more frequently had a family history of dementia (odds ratio, 3.61; confidence interval, 1.09 to 11.96) and laboratory evidence of proteinuria (odds ratio, 3.66; confidence interval, 1.54 to 8.71), had lower scores on neuropsychological tests, had more neurologic signs and symptoms, and were more functionally impaired in activities of daily living. Multiple logistic regression analysis showed that advanced age, lower educational attainment, history of myocardial infarction, and recent cigarette smoking were positively associated with case status and systolic blood pressure level was negatively associated with case status.
Cardiovascular disease risk factors may be modifiable predictors of dementia associated with cerebral infarction. Additional well-designed epidemiologic studies are needed to clarify these associations.
Reduction of stroke risk factors Kostis, John B; Gorelick, Philip B; Messerli, Franz H
Journal of clinical hypertension (Greenwich, Conn.),
01/2007, Letnik:
9, Številka:
1
Transcript
The radiological findings in 22 patients with malignant lymphoma of the nervous system are reviewed in relation to the clinical and histological features. The radiological findings were grouped into ...four major categories: intracranial, orbital, nasopharyngeal, and spinal. A fifth category, complications, was considered separately. The common neuroradiological manifestations of nervous system lymphoma are reviewed and compared with the recent literature.
Veblen's 1899 hypothesis that associated a female desire for thinness with the higher social classes was tested with data from a representative national sample of adolescents, 12 to 17 years of age, ...in the National Health Examination Survey. Controlling for the actual level of fatness, adolescent females in higher social classes wanted to be thinner more often than those in lower classes. The greater female desire for thinness was not the product of health information nor of sex differences in the level of fatness. The thinner the female, the greater the impact of social class on the desire for thinness. During puberty, adolescent females negatively evaluated the body fat associated with normal sexual development.
