The mitigation potential of vegetation-driven biophysical effects is strongly influenced by the background climate and will therefore be influenced by global warming. Based on an ensemble of remote ...sensing datasets, here we first estimate the temperature sensitivities to changes in leaf area over the period 2003-2014 as a function of key environmental drivers. These sensitivities are then used to predict temperature changes induced by future leaf area dynamics under four scenarios. Results show that by 2100, under high-emission scenario, greening will likely mitigate land warming by 0.71 ± 0.40 °C, and 83% of such effect (0.59 ± 0.41 °C) is driven by the increase in plant carbon sequestration, while the remaining cooling (0.12 ± 0.05 °C) is due to biophysical land-atmosphere interactions. In addition, our results show a large potential of vegetation to reduce future land warming in the very-stringent scenario (35 ± 20% of the overall warming signal), whereas this effect is limited to 11 ± 6% under the high-emission scenario.
Gas exchange measurements were carried out on ash and oak trees in a forest plantation during three whole growing seasons characterized by different water availability (2001, 2002 and 2003). A ...quantitative limitation analysis was applied to estimate the effects of drought and leaf ontogeny on stomatal (S(L)) and non-stomatal limitations (NS(L)) to light-saturated net photosynthesis (A(max)), relative to the seasonal maximum rates obtained under conditions of optimal soil water content. Furthermore, based on combined gas exchange and chlorophyll fluorescence measurements, NS(L) was partitioned into a diffusive (due to a decrease in mesophyll conductance, MC(L)) and a biochemical component (due to a decrease in carboxylation capacity, B(L)). During the wettest year (2002), the seasonal pattern of both A(max) and stomatal conductance (g(sw)) was characterized in both species by a rapid increase during spring and a slight decline over the summer. However, with a moderate (year 2001) or a severe (year 2003) water stress, the summer decline of A(max) and g(sw) was more pronounced and increased with drought intensity (30-40% in 2001, 60-75% in 2003). The limitation analysis showed that during the spring and the autumn periods S(L), MC(L) and B(L) were of similar magnitude. By contrast, from the summer data it emerged that all the limitations increased with drought intensity, but their relative contribution changed. At mild to moderate water stress (corresponding to values of g(sw) > 100 mmol H2O m(-2) s(-1)) about two-thirds of the decline in A(max) was attributable to S(L). However, with increasing drought intensity, NS(L) increased more than S(L) and nearly equalled it when the stress was very severe (i.e. with g(sw) < 60 mmol H2O m(-2) s(-1)). Within NS(L), MC(L) represented the main component, except at the most severe water stress levels when it was equalled by B(L). It is concluded that diffusional limitations (i.e. S(L) + MC(L)) largely affect net assimilation during most of the year, whereas biochemical limitations are quantitatively important only during leaf development and senescence or with severe droughts.
Due to production, usage and disposal of nano-enabled products as well as fragmentation of bulk materials, anthropogenic nanoscale particles (NPs) can enter the natural environment and through ...different compartments (air, soil and water) end up into the sea. With the continuous increase of production and associated emissions and discharges, they can reach concentrations able to exceed toxicity-thresholds for living species inhabiting marine coastal areas. Behavior and fate of NPs in marine waters are driven by transformation processes occurring as a function of NP intrinsic and extrinsic properties in the receiving seawaters. All those aspects have been overlooked in ecological risk assessment. This review critically reports ecotoxicity studies in which size distribution, surface charges and bio-nanointeractions have been considered for a more realistic risk assessment of NPs in marine environment. Two emerging and relevant NPs, the metal-based titanium dioxide (TiO2), and the polystyrene (PS), a proxy for nanoplastics, are reviewed and their impact on marine biota (from planktonic species to invertebrates and fish) discussed as a function of particle size and surface charges (negative vs positive) which affect their behavior and interaction with the biological material. Uptake of NPs is related to their nanoscale size, however in vivo studies clearly demonstrated that transformation (agglomerates/aggregates) occurring in both artificial and natural seawater drive to different exposure routes and biological responses at cellular and organism level. Adsorption of single particles or agglomerates onto the body surface or their internalization in feces can impair motility and affect sinking or floating behavior with consequences on population and ecological function. Particle complex dynamics in natural seawater is almost unknown although it determines the effective exposure scenarios. Based on the latest predicted environmental concentrations for TiO2 and PS NPs in the marine environment, current knowledge gaps and future research challenges encompass the comprehensive study of bio-nano interactions. As such, the analysis of NP biomolecular coronas can enable a better assessment of particle uptake and related cellular pathways leading to toxic effects. Moreover, the formation of an environmentally-derived corona (i.e. eco-corona) in seawater accounts for NP physical-chemical alterations, rebounding on interaction with living organisms and toxicity.
While a growing body of research highlights a bi-directional link between diabetes and mood disorders, little is known about the relationship between diabetes and obsessive-compulsive disorder (OCD). ...The aim of the present review is to investigate current evidence linking OCD, insulin-signaling and diabetes.
A PubMed search was conducted to review all the available studies assessing diabetes, glucose metabolism and insulin-signaling in OCD patients and vice versa.
Some clinical and epidemiological studies show a higher prevalence of diabetes in OCD and vice versa compared to the general population. Animal and genetic studies suggest a possible role of insulin-signaling in the pathophysiology of OCD. Deep brain stimulation (DBS) studies suggest that abnormal dopaminergic transmission in the striatum may contribute to impaired insulin sensitivity in OCD. While DBS seems to increase insulin sensitivity, a possible protective role of serotonin reuptake-inhibitors on diabetic risk needs further studies.
Despite their preliminary nature, these data highlight the importance of further investigations aimed at assessing metabolic features in OCD patients and OCD symptoms in diabetes patients to understand the impact of each condition on the pathophysiology and course of the other. Understanding the role of insulin in the obsessive-compulsive brain could open new treatment pathways for OCD.
•Some studies show a higher prevalence of diabetes in OCD and vice versa compared to the general population.•Animal and genetic studies suggest a possible role of insulin-signaling in the pathophysiology of OCD and DBS) studies suggest that abnormal dopaminergic transmission in the striatum may contribute to impaired insulin sensitivity in OCD.•While DBS seems to increase insulin sensitivity, a possible protective role of serotonin reuptake-inhibitors on diabetic risk need further studies.•These preliminary data highlight the importance of a deep clinical assessment and management of metabolic factors in OCD patients.
Land‐based climate mitigation measures have gained significant attention and importance in public and private sector climate policies. Building on previous studies, we refine and update the ...mitigation potentials for 20 land‐based measures in >200 countries and five regions, comparing “bottom‐up” sectoral estimates with integrated assessment models (IAMs). We also assess implementation feasibility at the country level. Cost‐effective (available up to $100/tCO2eq) land‐based mitigation is 8–13.8 GtCO2eq yr−1 between 2020 and 2050, with the bottom end of this range representing the IAM median and the upper end representing the sectoral estimate. The cost‐effective sectoral estimate is about 40% of available technical potential and is in line with achieving a 1.5°C pathway in 2050. Compared to technical potentials, cost‐effective estimates represent a more realistic and actionable target for policy. The cost‐effective potential is approximately 50% from forests and other ecosystems, 35% from agriculture, and 15% from demand‐side measures. The potential varies sixfold across the five regions assessed (0.75–4.8 GtCO2eq yr−1) and the top 15 countries account for about 60% of the global potential. Protection of forests and other ecosystems and demand‐side measures present particularly high mitigation efficiency, high provision of co‐benefits, and relatively lower costs. The feasibility assessment suggests that governance, economic investment, and socio‐cultural conditions influence the likelihood that land‐based mitigation potentials are realized. A substantial portion of potential (80%) is in developing countries and LDCs, where feasibility barriers are of greatest concern. Assisting countries to overcome barriers may result in significant quantities of near‐term, low‐cost mitigation while locally achieving important climate adaptation and development benefits. Opportunities among countries vary widely depending on types of land‐based measures available, their potential co‐benefits and risks, and their feasibility. Enhanced investments and country‐specific plans that accommodate this complexity are urgently needed to realize the large global potential from improved land stewardship.
We refine and update the mitigation potentials for 20 land‐based measures in >200 countries and five regions, comparing “bottom‐up” sectoral estimates with integrated assessment models (IAMs). The likely range of cost‐effective (available up to $100/tCO2eq) land‐based mitigation potential is 8–13.8 GtCO2eq yr−1 between 2020 and 2050. Mitigation potential varies sixfold across the five regions assessed (0.75–4.8 GtCO2eq yr−1) and the top 15 countries account for about 60% of the global potential. Opportunities among countries vary widely depending on types of land‐based measures available, their potential co‐benefits and risks, and their feasibility.
•Biophysical effects of LULCC are still ignored in international climate treaties•We provide a tier-based approach to account for the local component of such effects•It relies on potential changes in ...air temperature derived from remote sensing
Land use and land cover change (LULCC) affects the climate through both biogeochemical (BGC) and biophysical (BPH) mechanisms. While BGC effects are assessed at global scale and are at the heart of climate treaties such as the Paris Agreement, BPH effects are totally absent despite their increasingly recognized impact, especially at local scale. This stems from the complexity in characterizing their climate impacts both at local and global scale, which makes it impractical to offer clear advices for the development of climate policies. To overcome this barrier, we built a prototype for an assessment tool to evaluate the local BPH impact of a series of land cover transitions. It relies on a dedicated methodology, based on satellite remote sensing data, that can estimate the local change in near surface air temperature associated with BPH effects of potential LULCC. This tool follows a tiered methodological approach, using transparent methods and mirroring what is currently provided by the IPCC to estimate the BGC effects, i.e. through different levels of increasing methodological complexity, from Tier 1 (i.e. default method and factors) to Tier 2 (i.e. similar to Tier 1 but with higher level of details and complexity) and Tier 3 (i.e. tailored solution to address national circumstances). The prototype tool enables the evaluation of the local impacts of land-related BPH effects, therefore facilitating a scientifically informed and comprehensive assessment of land-based climate policies.
A growing body of literature suggests a link between bowel syndromes (e.g., irritable bowel syndrome and inflammatory bowel disease), gut microbiome alterations, and psychiatric disorders. This ...narrative review aims to explore the potential role of the gut microbiome in the pathogenesis and clinical presentation of obsessive–compulsive disorder (OCD) and to explore whether there is sufficient evidence to warrant considering gastrointestinal symptoms and their implication for the gut microbiome during the assessment and treatment of OCD. For this purpose, a PubMed search of studies focusing on OCD, gut microbiota, irritable bowel syndrome, and inflammatory bowel disease was conducted by two independent reviewers. While the current literature on gut microbiome and gastrointestinal issues in OCD remains limited, emerging evidence suggests gut microbiome alterations and high rates of bowel syndromes in this population. These findings emphasize the importance of incorporating comprehensive gastrointestinal assessments into the “global assessment of OCD”. Such assessment should encompass various factors, including gastrointestinal physical comorbidities and symptoms, nutritional habits, bowel habits, fluid intake, exercise patterns, and potential microbiome dysfunctions and inflammation. Considering the treatment implications, interventions targeting gut health, such as probiotics and dietary modifications, may hold promise in improving symptoms in OCD patients with comorbid gastrointestinal problems. Further research in this area is warranted to better understand the interplay between gut health and OCD and to explore the effectiveness of targeted interventions in improving clinical outcomes.
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