Survival from breast cancer (BC) is influenced by the timeliness of diagnosis and appropriateness of treatment, and may constitute a measure of the global effectiveness of a healthcare system. As the ...healthcare systems of several European Latin countries have some similarities, the search for differences in cancer survival may provide interesting information on the efficacy of these systems. The SUDCAN study is a collaboration between the Group for Epidemiology and Cancer Registration in Latin language countries (GRELL) and EUROCARE. BC data from six countries (Belgium, France, Italy, Portugal, Spain, and Switzerland) were extracted from the EUROCARE-5 database. First, we focus on 1- and 5-year age-standardized net survival (NS) from BC by country over the 2000–2004 period. Then, trends in NS over the 1989–2004 period and changes in the pattern of cancer excess mortality rate (EMR) up to 5 years after diagnosis were examined using a multivariate EMR model. There were little differences in age-standardized NS from BC. Over the 2000–2004 period, the 5-year survival ranged between 82 (Spain, Belgium, and Portugal) and 86% (France). There was an increase in age-standardized survival between 1989 and 2004 at 1 year as well as at 5 years. This increase was observed at all ages and in all countries. There was a decrease in the cancer EMR both immediately after diagnosis and by the second and third year of follow-up. There were only minor differences in survival from BC between European Latin countries. The general improvement in NS is presumably because of advances in early cancer diagnosis and improvements in treatment.
A search for squarks in
R
-parity violating supersymmetry is performed in
e
±
p
collisions at HERA using the H1 detector. The full data sample taken at a centre-of-mass energy
GeV is used for the ...analysis, corresponding to an integrated luminosity of 255 pb
−1
of
e
+
p
and 183 pb
−1
of
e
−
p
collision data. The resonant production of squarks via a Yukawa coupling
λ
′ is considered, taking into account direct and indirect
R
-parity violating decay modes. Final states with jets and leptons are investigated. No evidence for squark production is found and mass dependent limits on
λ
′ are obtained in the framework of the Minimal Supersymmetric Standard Model and in the Minimal Supergravity Model. In the considered part of the parameter space, for a Yukawa coupling of electromagnetic strength
λ
′=0.3, squarks of all flavours are excluded up to masses of 275 GeV at 95% confidence level, with down-type squarks further excluded up to masses of 290 GeV.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Survival is a key measure of the effectiveness of a healthcare system. European Latin countries have some similarities in their health systems; it is thus interesting to examine their differences in ...survival from cancer, here, lung cancer. The aim of the SUDCAN collaborative study was to compare the trends in the 1- and 5-year net survival from lung cancer and the trends in the excess mortality rates between six European Latin countries (Belgium, France, Italy, Portugal, Spain and Switzerland). The data were extracted from the EUROCARE-5 database. First, the net survival was studied over the 2000–2004 period using Pohar-Perme estimator. For trend analyses, the study period was specific to each country. The results are reported from 1992 to 2004 in France, Italy, Spain and Switzerland and from 2000 to 2004 in Belgium and Portugal. The analyses were carried out using a flexible excess rate modelling. Overall, the 1-year net survival from lung cancer ranged between 36 (Spain) and 43% (Belgium and Switzerland) and the 5-year net survival ranged between 11 (Spain) and 15% (Belgium and Switzerland). Between 1992 and 2004, the age-standardized survival increased considerably at 1 year, but increased less at 5 years after diagnosis. This increase was observed at ages 60 and 70, but was less obvious at age 80. There was little difference in net survival from lung cancer between European Latin countries, particularly in the more recent years. However, survival was slightly lower in Spain and Portugal than in France, Italy, Belgium and Switzerland. High-resolution studies with data on treatment, stage at diagnosis and comorbidities are needed to understand the reasons for these differences.
A search for events containing an isolated electron or muon and missing transverse momentum produced in
e
±
p
collisions is performed with the H1 and ZEUS detectors at HERA. The data were taken in ...the period 1994–2007 and correspond to an integrated luminosity of 0.98 fb
−1
. The observed event yields are in good overall agreement with the Standard Model prediction, which is dominated by single W production. In the
e
+
p
data, at large hadronic transverse momentum
P
T
X
> 25GeV, a total of 23 events are observed compared to a prediction of 14.0 ± 1.9. The total single
W
boson production cross section is measured as 1.06 ± 0.16 (stat.) ± 0.07 (sys.) pb, in agreement with an Standard Model (SM) expectation of 1.26 ± 0.19 pb.
The production of isolated photons in deep-inelastic scattering ep→eγX is measured with the H1 detector at HERA. The measurement is performed in the kinematic range of negative four-momentum transfer ...squared 4<Q
2
<150 GeV
2
and a mass of the hadronic system W
X
>50 GeV. The analysis is based on a total integrated luminosity of 227 pb
-1
. The production cross section of isolated photons with a transverse energy in the range 3<E
T
γ
<10 GeV and pseudorapidity range -1.2<η
γ
<1.8 is measured as a function of E
T
γ
, η
γ
and Q
2
. Isolated photon cross sections are also measured for events with no jets or at least one hadronic jet. The measurements are compared with predictions from Monte Carlo generators modelling the photon radiation from the quark and the electron lines, as well as with calculations at leading and next to leading order in the strong coupling. The predictions significantly underestimate the measured cross sections.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Cancer survival is a key measure of the effectiveness of a healthcare system. As differences in healthcare systems are present among European Latin countries, it is of interest to look specifically ...at their similarities and differences in terms of cancer survival. Incident cases were extracted from the EUROCARE-V database for France, Italy, Spain, Switzerland, Portugal, and Belgium. One and 5-year net survivals (NS) were calculated for the period 2000–2004 using the Pohar-Perme estimator. Trends in NS over the 1992–2004 period and changes in the pattern of cancer excess mortality rate until 5 years after diagnosis were examined using a multivariate excess mortality rate model. There were moderate differences in age-standardized NS between countries (5-year NS range: 83–88%), but significant differences in the age groups 15–54 and 55–74 years (at 5 years up to + 16 and + 18% between any two countries). During the study period, excess mortality and NS improved in Italy, Spain, and Portugal. In Italy and Portugal, this improvement was slightly similar at ages 40, 55, and 70 whereas, in Spain, there was a sharp increase in NS at age 55. Because of this improvement, excess mortality and NS were similar in all six countries in 2004. Excess mortality peaked around 1 year after diagnosis in the youngest ages, but decreased gradually in the elderly. Detailed analyses showed differences in excess mortality and NS from cervical cancer between European Latin countries. However, these differences decreased over the study period because of the considerable improvement in Spain, Italy, and Portugal.
In September 2020, a global aerosol forecasting model was implemented as an ensemble member of the National Oceanic and Atmospheric Administration (NOAA) National Centers for Environmental Prediction ...(NCEP) Global Ensemble Forecasting System (GEFS) v12.0.1 (hereafter referred to as “GEFS-Aerosols”). In this study, GEFS-Aerosols simulation results from 1 September 2019 to 30 September 2020 were evaluated using an aerosol budget analysis. These results were compared with results from other global models as well as reanalysis data. From this analysis, the global average lifetimes of black carbon (BC), organic carbon (OC), dust, sea salt, and sulfate are 4.06, 4.29, 4.59, 0.34, and 3.3 d, respectively, with the annual average loads of 0.14, 1.29, 4.52, 6.80, and 0.51 Tg. Compared with the National Aeronautics and Space Administration (NASA) Goddard Earth Observing System–Goddard Chemistry Aerosol and Radiation Transport (GEOS4-GOCART) model, the aerosols in GEFS-Aerosols have a relatively short lifetime because of the faster removal processes in GEFS-Aerosols. Meanwhile, in GEFS-Aerosols, aerosol emissions are the determining factor for the mass and composition of aerosols in the atmosphere. The size (bin) distribution of aerosol emissions is as important as its total emissions, especially in simulations of dust and sea salt. Moreover, most importantly, the strong monthly and interannual variations in natural sources of aerosols in GEFS-Aerosols suggest that improving the accuracy of the prognostic concentrations of aerosols is important for applying aerosol feedback to weather and climate predictions.
Gastric cancers are a clinical challenge. The aim of the SUDCAN collaborative study was to compare the net survival from gastric cancer between six European Latin countries (Belgium, France, Italy, ...Portugal, Spain and Switzerland) and explore the trends in net survival and in the dynamics of the excess mortality rates (EMRs) up to 5 years after diagnosis. The data were extracted from the EUROCARE-5 database. First, net survival was studied over the period 2000–2004 using the Pohar-Perme estimator. For trend analyses, the study period was specific to each country. The results are reported from 1992 to 2004 in France, Italy, Spain and Switzerland and from 2000 to 2004 in Belgium and Portugal. These trend analyses were carried out using a flexible excess rate modelling strategy. There were little differences between countries in age-standardized net survival for stomach cancer (2000–2004). The 5-year net survival ranged between 26 (Spain) and 32% (Italy). There was a small increase in the age-standardized net survival at 1 year between 1992 and 2004. The increase was also observed in the 5-year net survival, except in France, where the increase was less marked. A slight decrease in the EMR between 1992 and 2004 was limited to the 24 months after diagnosis. In addition, the decrease in the EMR was the same whatever the year of diagnosis. There were minor differences in survival from stomach cancer between European Latin countries. A slight improvement in the 5-year net survival was observed in all countries and the major gain was observed during the 24 months after diagnosis. Development of innovative treatments is needed to improve the prognosis.
Liver cancer represents a major clinical challenge. The aim of the SUDCAN collaborative study was to compare the net survival from liver cancer between six European Latin countries (Belgium, France, ...Italy, Portugal, Spain and Switzerland) and provide trends in net survival and dynamics of excess mortality rates (EMRs) up to 5 years after diagnosis. The data were extracted from the EUROCARE-5 database. First, net survival was studied over the period 2000–2004 using the Pohar-Perme estimator. For trend analyses, the study period was specific to each country. Results are reported from 1992 to 2004 in France, Italy, Spain and Switzerland and from 2000 to 2004 in Belgium and Portugal. These trend analyses were carried out using a flexible excess-rate modeling strategy. There were little differences between the six countries in the 5-year age-standardized net survival (2000–2004): it ranged from 13% (France and Portugal) to 16% (Belgium). An increase in the net age-standardized survival was observed in all countries between 1992 and 2004, both at 1 year and at 5 years (the highest in Spain, the lowest in France). Generally, patients aged 60 years showed the highest increase. There was a progressive decrease in EMR over the 5-year- period following diagnosis. The study confirmed the poor prognosis of liver cancer. Innovative treatments might improve the prognosis as well as preventive screening of cirrhotic patients with good liver function. Efforts are also needed to improve registration practices.
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