Calcifying epithelial odontogenic tumor (CEOT), or the Pindborg tumor, is very rare neoplasm, which accounts up to 1% of all odontogenic tumors. These tumors involve mandible almost twice as common ...as the maxillary bone, mostly in the premolar and molar region and present at first with local swelling. There is no gender predilection and the tumor usually appears between 2nd and 6th decade of life. We report the case of a 36-year-old male patient with a Pindborg tumor in the maxillary region on the right side, also involving the adjacent maxillary sinus, with destroying of the local anatomical structures. Complete surgical excision of the tumor has been performed and four years after surgical treatment, there is no sign of recurrence.
Bone morphogenetic protein 6 (BMP6) has unique properties regarding structure and function in supporting bone formation during development and adult life. Despite its known role in various malignant ...tumors, the prognostic significance of BMP6 expression in oral squamous cell carcinoma (OSCC) remains unknown. The aim of the study was to investigate immunohistochemical expression of BMP6 in OSCC in correlation with clinical and pathological parameters, disease recurrence and survival. In addition, we investigated other parameters in order to identify prognosticators of neck metastases and final outcome. The study included 120 patients with clinically T1-3N0 OSCC who were primarily surgically treated between 2003 and 2008. There were 99 (82.5%) male and 21 (17.5%) female patients. The five-year disease-specific survival for the whole cohort was 79.7%. Tumors smaller than 2 cm in diameter showed higher incidence of strong BMP6 expression. No statistical correlation was observed between other clinico-pathological factors and BMP6 expression. Expression of BMP6 was not associated with disease recurrence and survival. BMP6 may not serve as prognosticator of final outcome or recurrence in clinically node-negative OSCC subjects. In multivariate analysis predictors of poorer survival were positive surgical margin, moderate tumor cell differentiation and pathological involvement of levels IV and/or V.
The aim of this in vitro study was to compare the sealing effectiveness of the Erbium:YAG laser to the sealing effectiveness of an ultrasonic device in the preparation of similar retrograde cavities ...using different retrograde filling materials. After root-canal instrumentation and filling, apices of 60 single-rooted teeth were resected. Retrograde class I cavities 3 mm deep were prepared using an ultrasonic device (group A) and Er:YAG laser (group B). An ultrasonic unit was used with CT-5 retrotip at the frequency of 32 KHz. Laser beam parameters were a pulse of very short duration (100 μs), energy of 280 mJ, and repetition rate of 10 Hz. Cavities of each group of 10 samples were filled with mineral trioxide aggregate (MTA), Super-EBA, and IRM. Microleakage was measured using a fluid transport model. The results showed that cavities prepared with Er:YAG laser have significantly lower microleakage for all tested materials.
Calcifying epithelial odontogenic tumor (CEOT), or the Pindborg tumor, is very rare neoplasm, which accounts up to 1% of all odontogenic tumors. These tumors involve mandible almost twice as common ...as the maxillary bone, mostly in the premolar and molar region and present at first with local swelling. There is no gender predilection and the tumor usually appears between 2nd and 6th decade of life. We report the case of a 36-year-old male patient with a Pindborg tumor in the maxillary region on the right side, also involving the adjacent maxillary sinus, with destroying of the local
anatomical structures. Complete surgical excision of the tumor has been performed and four years after surgical treatment, there is no sign of recurrence.
The authors present a new design of splintage for fixation of the alveolar ridge mucosa following various vestibuloplasty procedures. From 1981-1987 50 acrylic buccal splints and 76 palatal splints ...were used, fixed by AO screws, in vestibuloplasty procedures. By using screws a controlled pressure equally distributed over the mucosa was achieved. The results demonstrate that screw fixation of the splints can avoid some of the common problems found especially with suture or nails. The acrylic buccal splint fixed by AO screws on to the alveolar bone is more convenient for the patient and produces a better operative result. The authors recommend it as the method of choice for submucosal and some modified submucosal vestibuloplasties.
Autori prikazuju četiri slučaja idiopatskih koštanih šupljina mandibule koje su u zadnjih pet godina registrirali u Klinici za kirurgiju lica, čeljusti i usta Medicinskog i Stomatološkog fakulteta u ...Zagrebu. U jednom slučaju postojale su i subjektivne smetnje, pa je to bilo razlogom da se izvrši operativni zahvat. Patohistološki nalaz potvrdio je nalaz sijalografije i nalaz u toku operacijskog zahvata, da se u šupljini nalazilo ektopično tkivo žlijezde slinovnice. U ostalim slučajevima lezije su bile asimptomatske te se povremeno rendgenološki kontroliraju, što je i stav većine autora koji su o tom problemu pisali. Dan je pregled svjetske literature od prvih opisa tih lezija i iznesena su značajnija stajališta pojedinih autora o tom problemu.
Autori polaze od saznanja da, u pravilu, postoji hipertrofija (hiperplazija) submukoze i da je tu glavna masa hiperplastičnog tkiva, a sluznica se hipertrofijom samo prilagodi uvećanoj i ...promijenjenoj podlozi. Hipertrofija sluznice se razvija na atrofičnom grebenu, kao posljedica atrofije alveolnog nastavka. Prema tomu, treba riješiti hipertrofiju sluznice, ali istovremeno i atrofiju alveolnog grebena, jer se inače ne otklanja uzrok hipertrofije. , Ova saznanja omogućila su autorima da sistematiziraju materijal, a time i probleme i operativne metode za njihovo rješavanje. Hipertrofija mekih tkiva se može razviti na dijelu alveolnog grebena, ili na cijelom alveolnom nastavku. Najčešće je u pomičnoj sluznici, na rubu krila proteze, ali može zahvatiti cijelu pomičnu sluznicu, ili gingivu propriju. Ove se lokalizacije mogu kombinirati. Isto je tako oblik hipertrofične sluznice vrlo raznolik u pojedinoj lokalizaciji, ali i na istoj lokalizaciji može biti vrlo različite konfiguracije. Svi ovi različiti problemi uvjetuju i izbor operativnih metoda, bilo da se u jednom zahvatu upotrebljava jedna metoda ili kombinacija dviju pa i više metoda. Operativni plan treba da predvidi konačni rezultat, izborom podesne operativne metode, kao i ponašanje raznih pa i promijenjenih tkiva u njihovim uzajamnim odnosima. Relevantan je rezultat, jer je on cilj, ali nisu irelevantni postupci, koji do njega dovode. Uspoređivanjem različitih operativnih metoda, s obzirom na hipertrofično stanje i postignuti operativni rezultat,ustvari je vrednovanje svake pojedine metode. Vrednovanje operativnih metoda, na konkretnom materijalu, rezultira sistematizacijom i bolesnih stanja i svrsishodnih metoda za rješavanje tih i takvih stanja. Autori zatim sistematiziraju operativne metode, s obzirom na lokalizaciju hipertrofije, njenu veličinu i konfiguraciju. Određuju uvjete kad se može upotrijebiti samo ekscizija hipertrofije, kad ekscizija do periosta, transplantat sluznice ili kože (Tierschovkalem). Govore o namjeni metoda izrađenih u Zavodu za oralnu kirurgiju Stomatološkog fakulteta u Zagrebu , kao što su otvorena metoda, zatvorena metoda i replantacija hipertrofične sluznice, koje istovremeno rješavaju atrofiju alveolnog grebena i hipertrofiju sluznice. Kombinacijom tih metoda mogu se riješiti hipertrofije bilo kojeg opsega, lokalizacije i konfiguracije, na vrlo adekvatan način.
Klinička dijagnoza, tj. klinički izgled patološke promjene, često ne otkriva pravu narav bolesti i tek patohistološka analiza potvrdi ili odbaci kliničku dijagnozu. Zajednički rad oralnog kirurga i ...patologa
osigurava postavljanje točne dijagnoze. Retrospektivno smo usporedili kliničku i patohistološku dijagnozu ambulantno operiranih
bolesnika tijekom 1990. godine. Apikotomija, alveotomija i cistektomija najčešće su izvedeni operacijski zahvati. Na patohistološki pregled upućeno je 278 uzoraka tkiva. Najčešće dijagnoze pod kojima smo slali materijal na patohistološku pretragu jesu cista (45%), fibroma (12,6%) i epulis (9,7%). Prosječna podudarnost kliničke i patohistološke dijagnoze iznosi 70%, a analizirana je za svaku kliničku dijagnozu posebno. U jednog bolesnika je za klinički benignu promjenu — hiperkeratozu, patohistološka dijagnoza glasila carcinoma planocellulare. Autori raspravljaju o potrebi patohistološke potvrde kliničke dijagnoze i ističu važnost i opravdanost patohistološkog pregleda svakog odstranjenog tkiva.
