Current status of the BAIKAL-GVD project Avrorin, A.V.; Aynutdinov, V.M.; Belolaptikov, I.A. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
10/2013, Letnik:
725
Journal Article
Recenzirano
We present a status of the Baikal-GVD Project. The objective of this project is a construction of a km3-scale neutrino telescope in the Lake Baikal. As an important milestone, the first GVD ...engineering array has been deployed and ran in April, 2011. Application of a completely new technology gave us an opportunity to study all the basic elements of the future full detector and to finalize the GVD technical design. We discuss the configuration and the design of the engineering array as well as data performance with the preliminary results.
A corrected energy dependence of the depth of the maximum in the wide range of energies 10
15
to 10
18
eV is obtained using data collected at the Tunka-133 facility over 7 years of operation ...(2009–2017) and the TAIGA-HiSCORE facility in the 2019–2020 season. At the highest energies, our results match those of the Pierre Auger observatory. The results are converted to parameter ❬ln
A
❭, which characterizes the mean EAS composition.
The influence of sodium polyacrylate on the disaggregation kinetics and threshold of conglomerates of a natural agromineral, zeolite, under ultrasonic dispersion has been studied. It has been ...demonstrated that the use of sodium polyacrylate as a stabilizing additive has resulted in the reduction of the zeolite particle size, the increase in the content of isolated fractions, and significant decrease in the ultrasonic treatment duration. When the zeolite was dispersed with sodium polyacrylate, the particles achieved an average size of 750.0 nm after the first minute of cavitation treatment, while the dispersion of the agromineral without the additive required a 5-min treatment to achieve the same result. The use of sodium polyacrylate increased the stabilized state period of zeolite particles to half a year.
Over the past few years, the TAIGA (Tunka Advanced Instrument for cosmic ray physics and Gamma-ray Astronomy) observatory has been being deployed in the Tunka Valley, Republic of Buryatia. It is ...designed for studying gamma rays of energy above 30 TeV and performing searches for sources of galactic cosmic rays with energies in the vicinity of 1 PeV, which is an energy region around the classic knee in the cosmic-ray energy spectrum. The first phase of the observatory will be situated at a distance of about 50 km from Lake Baikal at the site of the Tunka-133 array. The TAIGA gamma observatory will include a network of 500 wide-angle (0.6 sr) Cherenkov detectors (TAIGA-HiSCORE array) and up to 16 atmospheric Cherenkov telescopes (ACT) designed for analyzing the EAS images (imaging atmospheric Cherenkov telescopes, or IACT) and positioned within an area of 5 km
2
. The observatory will also include muon detectors of total area 2000 m
2
distributed over an area of 1 km
2
. Within the next three years, it is planned to enhance the area of the TAIGA-HiSCORE array by a factor of four—from 0.25 km
2
to 1 km
2
; to supplement the existing IACT with two new ones; and to deploy new muon detectors with a total coverage of 200 m
2
. The structure of the new observatory is described along with the data analysis techniques used. The most interesting physical results are presented, and the research program for the future is discussed.
alpha-Latrotoxin, a black widow spider neurotoxin, can bind to high affinity receptors on the presynaptic plasma membrane and stimulate massive neurotransmitter release in the absence of Ca2+. ...Neurexins, previously isolated as alpha-latrotoxin receptors, require Ca2+ for their interaction with the toxin and, thus, may not participate in the Ca2+-independent alpha-latrotoxin activity. We now report the isolation of a novel protein that binds alpha-latrotoxin with high affinity in the presence of various divalent cations (Ca2+, Mg2+, Ba2+, and Sr2+) as well as in EDTA. This protein, termed here latrophilin, has been purified from detergent-solubilized bovine brain membranes by affinity chromatography on immobilized alpha-latrotoxin and concentrated on a wheat germ agglutinin affinity column. The single polypeptide chain of latrophilin is N-glycosylated and has an apparent molecular weight of 120,000. Sucrose gradient centrifugations demonstrated that latrophilin and alpha-latrotoxin form a stable equimolar complex. In the presence of the toxin, anti-alpha-latrotoxin antibodies precipitated iodinated latrophilin, whose binding to immobilized toxin was characterized by a dissociation constant of 0.5-0.7 nM. This presumably membrane-bound protein is localized to and differentially distributed among neuronal tissues, with about four times more latrophilin expressed in the cerebral cortex than in the cerebellum; subcellular fractionation showed that the protein is highly enriched in synaptosomal plasma membranes. Our data suggest that latrophilin may represent the Ca2+-independent receptor and/or molecular target for alpha-latrotoxin.
The Tunka-Grande experiment Monkhoev, R.D.; Budnev, N.M.; Chiavassa, A. ...
Journal of instrumentation,
06/2017, Letnik:
12, Številka:
6
Journal Article
Recenzirano
The investigation of energy spectrum and mass composition of primary cosmic rays in the energy range 1016–1018 eV and the search for diffuse cosmic gamma rays are of the great interest for ...understanding mechanisms and nature of high-energy particle sources, the problem of great importance in modern astrophysics. Tunka-Grande scintillator array is a part of the experimental complex TAIGA (Tunka Advanced Instrument for Cosmic Ray and Gamma Astronomy) which is located in the Tunka Valley, about 50 km from Lake Baikal. The purpose of this array is the study of diffuse gamma rays and cosmic rays of ultra-high energies by detecting extensive air showers. We describe the design, specifications of the read-out, data acquisition (DAQ) and control systems of the array.
Objective. Estimation of the effectiveness of low power brachytherapy sources I-125 in the combined treatment in group of patients of intermediate risk of localized prostate cancer.Material and ...methods. The study included 126 patients with prostate cancer of intermediate risk. 104 patients (83,9%) were conducted low power brachytherapy I‑125 in combination with hormone therapy by analogues of LHWG. 22 patients (16.1%) received external beam irradiation in combination with brachytherapy I‑125 and hormonal treatment. Relapse-free survival of patients was evaluated in accordance with the criteria Phoenix (Nadir PSA + ng/ml). Evaluation of side effects of radiation treatment were carried out according to the RTOG criteria.Results. PSA relapse-free survival in the group of brachytherapy and hormone treatment at the time of observation 5 years amounted to 97.1%. In the group of combined radiation therapy with brachytherapy, and hormonal treatment PSA relapse-free survival rate was 95.5%.In both groups, relapse-free survival was noted in 96,8% of cases. Tumor-specific and overall survival in bothgroups was 100%. The major complications of treatment in both groups were radiation urethritis 1 to 2 degrees in 9.5% of cases (12 patients), urethral stricture in 5 patients (3.9% of cases), acute urinary retention in 1 patient (0.8% of cases) and late radiation rectitis of 2 degree in 1.58% of cases (2 patients).Conclusions. It is possible to draw tentative conclusions about the high rate of survival without progression in both treatment groups on the background of the relatively low frequency of adverse reactions. It is necessary further follow-up for patients with estimating of survival for a longer period.
The more correct recalculation from the measured Cherenkov light fluxes at distances of 200 (Q200) and 100 (Q100) m from the Extensive Air Shower (EAS) core to the energy of the primary particle has ...been developed using the results of M-C simulation by the CORSIKA code, assuming a light primary composition of cosmic rays. Using the new conversion expressions, a differential energy spectrum was obtained according to the data of the Tunka-133 array for 7 years of operation and the TAIGA-HiSCORE array for 2 years of operation.
Status and First Results of TAIGA Tluczykont, M.; Astapov, I. I.; Awad, A. K. ...
Physics of atomic nuclei,
11/2021, Letnik:
84, Številka:
6
Journal Article
Recenzirano
The Tunka Advanced Instrument for Gamma-ray and cosmic ray Astrophysics (TAIGA) is a hybrid experiment for the measurement of Extensive Air Showers (EAS) with good spectral resolution in the TeV to ...PeV energy range. In this domain, the long-sought Pevatrons can be detected. Currently the TAIGA detector complex combines a two wide angle shower front Cherenkov light sampling timing arrays (HiSCORE and Tunka-133), two 4 m class, 10
aperture Imaging Air Cherenkov Telescopes (IACTs) and 240 m
surface and underground charged particle detector stations. Our goal is to introduce a new hybrid reconstruction technique, combining the good angular and shower core resolution of HiSCORE with the gamma-hadron separation power of imaging air Cherenkov telescopes. This approach allows to maximize the effective area and simultaneously to reach a good gamma-hadron separation at low energies (few teraelectronvolts). At higher energies, muon detectors are planned to enhance gamma-hadron separation. During the commissioning phase of the first and second IACT, several sources were observed. First detections of known sources with the first telescope show the functionality of the TAIGA IACTs. Here, the status of the TAIGA experiment will be presented, along with first results from the current configuration.
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