The flux of solvent water coupled to the transit of ions through protein pores is considerable. The effect of this electroosmotic solvent flow on the binding of a neutral ...molecule$\lbrack\beta\!-\!cyclodextrin\>(\beta CD)\rbrack$to sites within the staphylococcal α-hemolysin pore was investigated. Mutant α-hemolysin pores were used to which β CD can bind from either entrance and through which the direction of water flow can be controlled by choosing the charge selectivity of the pore and the polarity of the applied potential. The Kdvalues for β CD for individual mutant pores varied by >100-fold with the applied potential over a range of -120 to +120 mV. In all cases, the signs of the changes in binding free energy and the influence of potential on the association and dissociation rate constants for β CD were consistent with an electroosmotic effect.
► At the resonance frequency,
α
E,A in the axial mode increases linearly even though
H
DC
>
8000
Oe. ► The maximum of
α
E,V in the vertical mode with
H
DC
=
270
Oe is much higher than that with
H
DC
...=
7000
Oe. ► The ME voltage coefficient increases with cylinder diameter. ► The resonance frequency of cylindrical layered composites decreases with increasing cylinder diameter.
Magnetoelectric (ME) Ni–PZT–Ni cylindrical layered composites have been prepared by electroless deposition. The ME effect was measured by applying both constant and alternating magnetic fields parallel and perpendicular to the cylinder axis direction. The ME voltage coefficient increases with cylinder diameter. Both experimental and calculated data indicate that the resonance frequency of Ni–PZT–Ni cylindrical layered composites decreases with increasing cylinder diameter. We can apply this characteristic of resonance frequency to design a kind of ME composites with the controllable resonance ME coupling.
Monoclinic NH4V3O8 single-crystalline nanobelts with widths of 80−180 nm, thicknesses of 50−100 nm, and lengths up to tens of micrometers have been synthesized at large scale in an ammonium ...metavanadate solution by a templates/catalysts-free route. Such nanobelts grow along the direction of 010. The individual NH4V3O8 nanobelt exhibits nonlinear, symmetric current/voltage (I/V) characteristics, with a conductivity of 0.1−1 S/cm at room temperature and a dielectric constant of ∼130. The dominant conduction mechanism is based on small polaron hopping due to ohmic mechanism at low electric field below 249 V/cm due to Schottky emission at medium electric field between 249 and 600 V/cm and due to the Poole−Frenkel emission mechanism at high field above 600 V/cm.
Future Physics Programme of BESIII Ahmed, S.; Amoroso, A.; Bennett, J. V. ...
Chinese Physics C, High Energy Physics and Nuclear Physics/Chinese physics C,
04/2020, Letnik:
44, Številka:
4
Journal Article
Recenzirano
Odprti dostop
Abstract
There has recently been a dramatic renewal of interest in hadron spectroscopy and charm physics. This renaissance has been driven in part by the discovery of a plethora of charmonium-like
...XYZ
states at BESIII and
B
factories, and the observation of an intriguing proton-antiproton threshold enhancement and the possibly related
X
(1835) meson state at BESIII, as well as the threshold measurements of charm mesons and charm baryons.
We present a detailed survey of the important topics in tau-charm physics and hadron physics that can be further explored at BESIII during the remaining operation period of BEPCII. This survey will help in the optimization of the data-taking plan over the coming years, and provides physics motivation for the possible upgrade of BEPCII to higher luminosity.
Ba2Mg(B3O6)2 (BMBO) is a potential stimulated Raman scattering (SRS) crystal. In this work, a colorless transparent BMBO single crystal with a dimension of 32×23×7mm3 has been grown by the Kyropoulos ...method. A spontaneous Raman spectrum of the crystal was recorded at room temperature. Site group analysis and first-principles calculations were employed to interpret the Raman spectrum. The site group analysis results show that the total lattice modes are 10Ag+11Au+10Eg+11Eu, of which 10Ag+10Eg are Raman-active. The crystal Raman spectrum was computed in CASTEP (Cambridge Sequential Total Energy Package) using a hybrid method combining density functional perturbation theory with the finite displacement method. All of the Raman-active modes have been identified. The internal modes of the B3O6 ring in the crystal give rise to vibrations with Raman shifts above 220cm−1; the translations and the librations of the rings, as well as the translations of the Ba2+ cations, give rise to vibrations with Raman shifts below 220cm−1. The strongest peak at 645cm−1 in the experimental spectrum is assigned to the breathing mode of the B3O6 ring.
► BMBO single crystals were grown by the Kyropoulos method. ► The lattice vibriations have been classified by the method of site group analysis. ► First-principles calculations were employed to interpret the crystal Raman spectrum.
To explore the expression of circ-KEL in patients with acute myeloid leukemia (AML) and the effect and mechanism of circ-KEL on leukemic cells.
The expression of circ-KEL was detected by quantitative ...real-time polymerase chain reaction in bone marrow mononuclear cells collected from 116 patients with AML and 40 healthy donors. The correlation of circ-KEL expression with the clinical characteristics of patients with AML was further systematically analyzed. The modulations among circ-KEL, miR-335-5p, and LRG1 were predicted through bioinformatics analysis and validated by dual luciferase assay. Cell proliferation and apoptosis were detected using CCK8 and flow cytometry.
The expression of circ-KEL was significantly elevated in patients with AML compared with the healthy controls (Relative expression level, -Δct, AML: -7.117±1.831; control: -8.669±1.771,
<0.001) . Moreover, patients with high circ-KEL expression have significantly worse overall survival. The level of circ-KEL in patients with AML was downregulat
Objective: To explore the prognostic factors of extracellular NK/T cell lymphoma (ENKTL) treated with pegaspargase/L-asparaginase. Methods: The clinical data of 656 ENKTL patients diagnosed at 11 ...medical centers in the Huaihai Lymphoma Working Group from March 2014 to April 2021 were retrospectively analyzed. The patients were randomly divided into two groups: a training set (460 cases) and a validation set (196 cases) at 7∶3, and the prognostic factors of the patients were analyzed. A prognostic scoring system was established, and the predictive performance of different models was compared. Results: Patients' median age was 46 (34, 57) years, with 456 males (69.5% ) and 561 nasal involvement (85.5% ). 203 patients (30.9% ) received a chemotherapy regimen based on L-asparaginase combined with anthracyclines, and the 5-year overall survival rate of patients treated with P-GEMOX regimen (pegaspargase+gemcitabine+oxaliplatin) was better than those treated with SMILE regimen (methotrexate+dexamethasone+cyclophosp
Abstract
The relationship between geodesic acoustic modes (GAMs) and tearing modes (TMs), or locked modes (LMs), have been investigated in EAST. Firstly, multi-branch electromagnetic GAMs are ...observed synchronously after the excitation of TMs. Broadened radial coverage is observed for these branches, and these frequencies can be described by the dispersion relation of GAM. Secondly, multi-branch electromagnetic GAMs are generated after the excitation of LMs. The toroidal asymmetric structure of GAMs is excited due to the existence of 3D intrinsic error fields, and the radial distribution of those branches is altered accordingly. Four branches of electromagnetic GAMs are observed in the region that is closer to the ‘X’-point of the locked magnetic islands, which should be merged into two branches for the region that is closer to the ‘O’-point, as confirmed by XUV array measurement. Thirdly, a similar phenomenon is reproduced by the modulation of resonant magnetic perturbation (RMP). The frequency of GAM increases with the current of the RMP coils, and multi-branches of similar modes are generated when the current achieves
I
R
M
P
=
2.5
kA, where the electrostatic and electromagnetic components are altered accordingly. The features of those branches are modulated by the rotation of the RMP. Therefore, the structures of the pair of GAMs can be different, which should be influenced by the different magnetic topological structure.
Summary Background Although several methods of fat grafting have been reported, there is no agreement regarding which technique should be used for autologous fat grafting and the final outcome after ...fat grafting often depends on the technique used by a surgeon. In this report we present an integrated fat grafting technique developed over the years for cosmetic facial contouring. Method Fat grafts were harvested under low pressure with syringes, processed with low speed centrifugation, and then injected into the affected areas of the face with low volume for each pass via multi-tunnels, multi-planes, and multi-points. We describe the above integrated fat grafting technique as ‘3Ls and 3Ms’ technique. A total of 83 patients with temporal, cheek, and periocular hollowing, lean or aging face or facial asymmetry were injected with autologous fats between 1 and 3 times at interval of 3 to 6 months. All patients were evaluated clinically and followed up to 8 years. Results The absorption was found variable in different patients. Long-term follow-up proved that final correction after 1–3 injections of autologous fat had persisted for many years. Obviously improved facial contour was evident in most patients after autologous fat transplantations. More than 73.5% of the patients in this series were assessed as satisfactory by all 3 observers (patient, surgeon, and layerperson). Between 12.0% and 21.7% of the patients were mostly satisfactory. Less than 4.8% of the patients were unsatisfactory. Conclusions Autologous fat grafting to the face is a safe and reliable option to improve facial contour in patients. The transplanted fat can survive well in the face with our integrated fat grafting technique. More than one injection may be required to achieve optimal outcome.
PDF
