The Cryogenic Underground Observatory for Rare Events (CUORE) experiment is presently in the final phases of its commissioning at the Gran Sasso Underground Laboratory (Italy). The CUORE cryogenic ...system will have to guarantee the optimal operation temperature of the detector (∼ 10 mK) for a live-time of 5 years. Furthermore, to avoid radioactive background, about 7 tonnes of lead are cooled to below 4 K and only few construction materials are acceptable. The CUORE detector will be by far the largest mass ever cooled to 10 mK. A description of the CUORE cryostat is presented and the specific characteristics and the performances are illustrated. The results of the (recently concluded) cryostat commissioning are also reported. They show that the CUORE cryostat is now ready to host the detector, thus confirming the possibility of realizing large bolometric arrays for rare event physics.
The Cryogenic Underground Observatory for Rare Events (CUORE) will search for the 0vββ decay in 130Te using a cryogenic array of TeO2 bolometers, operated at a base temperature of ~10mK. CUORE will ...consist of a closely packed array of 19 towers each containing 52 crystals, for a total mass of 741kg. The detector assembly is hosted in one of the largest cryostats ever constructed and will be cooled down to base temperature using a custom-built cryogen free dilution refrigerator. The CUORE cryostat along with the pulse tube based dilution refrigerator has been already commissioned at Laboratori Nazionali del Gran Sasso (LNGS) and a record base temperature, on a cubic meter scale, of ~6mK was achieved during one of the integration runs. We present the results from integration runs, characterizing the system and the cooling performance of the dilution refrigerator, effectively showcasing its stability at base temperature for the expected thermal load.
The Cryogenic Underground Observatory for Rare Events (CUORE) is a 1-ton scale bolometric experiment. The CUORE detector is an array of 988 TeO
2
crystals arranged in a cylindrical, compact, and ...granular structure of 19 towers. These detectors will need a base temperature lower than 10 mK in order to meet the performance specifications. To cool the CUORE detector, a large cryogen free cryostat with five pulse tubes and one custom designed high power dilution refrigerator has been designed. The three vessels that form the outer shell of the CUORE cryostat were produced in 2012 and are now assembled in the Gran Sasso National Laboratories (LNGS). We report here the detailed description of the 4 K outer cryostat for the CUORE experiment together with the results of the validation tests done at the production site in 2012 and of the first commissioning to 4 K at LNGS in 2013.
•A large custom cryogen-free cryostat has been designed and built in order to operate the CUORE detector.•The CUORE cryostat has a 1 m3 experimental volume and is able to host a tonne-scale ...bolometric detector.•The CUORE cryostat guarantees a low noise and low radioactivity environment, needed to search for 0nbb.•The CUORE detector has been cooled down to 8.3 mK and steadily operated at 15 mK, proving the success of the cryostat.
The CUORE experiment is the world’s largest bolometric experiment. The detector consists of an array of 988 TeO2 crystals, for a total mass of 742 kg. CUORE is presently taking data at the Laboratori Nazionali del Gran Sasso, Italy, searching for the neutrinoless double beta decay of 130Te. A large custom cryogen-free cryostat allows reaching and maintaining a base temperature of ∼10 mK, required for the optimal operation of the detector. This apparatus has been designed in order to achieve a low noise environment, with minimal contribution to the radioactive background for the experiment. In this paper, we present an overview of the CUORE cryostat, together with a description of all its sub-systems, focusing on the solutions identified to satisfy the stringent requirements. We briefly illustrate the various phases of the cryostat commissioning and highlight the relevant steps and milestones achieved each time. Finally, we describe the successful cooldown of CUORE.
The CUORE experiment is the world's largest bolometric experiment. The detector consists of an array of 988 TeO2 crystals, for a total mass of 742 kg. CUORE is presently taking data at the Laboratori ...Nazionali del Gran Sasso, Italy, searching for the neutrinoless double beta decay of 130Te. A large custom cryogen-free cryostat allows reaching and maintaining a base temperature of ~10 mK, required for the optimal operation of the detector. This apparatus has been designed in order to achieve a low noise environment, with minimal contribution to the radioactive background for the experiment. In this paper, we present an overview of the CUORE cryostat, together with a description of all its sub-systems, focusing on the solutions identified to satisfy the stringent requirements. We briefly illustrate the various phases of the cryostat commissioning and highlight the relevant steps and milestones achieved each time. Finally, we describe the successful cooldown of CUORE.
What is the moral value of reading works of literature? Versions of this question, those which seek to understand the human import of literary works, are capable of challenging philosophical ...paradigms which require that which is morally significant for human beings to be circumscribed by and grounded in philosophical methods and principles. My dissertation provides an initial critique to a dominant manner of thinking about the moral value of literature—mostly focusing on the novel. Thus, it is also a critical contribution to a discussion of the relationship between philosophy and literature, what a proper philosophical engagement of literary works would be, and thereby an inquiry into the historical conventions that have implicitly or explicitly portrayed (moral or aesthetic) philosophy’s relationship to literature as the relationship between theory and practice. My methodology is broadly and loosely Wittgensteinian, one which is motivated by the problematic contours I discover in two prominent philosophical takes on the significance of the novel. This methodology, what I describe at the end as a Wittgensteinian poetics, is equally motivated by a longstanding crisis in moral theory as such. This crisis is one which is nevertheless codified into the pedagogy of ethics, and is equally related to the understanding of moral philosophy as providing an authoritative view on that which is significant for human life. I resolve these problems by relying upon readings of Wittgenstein in order to drive critical pressure towards what I identify as a Platonic framework which still, by and large, dominates the nexus of philosophy and literature. The dissolution of the apparent urgency of paradigmatic philosophical questions as fetishized or fantasy constructions, and the resultant dual appreciation of recognizing what is already open to view alongside of open-ended reflective questions (i.e., questions pertaining more to what the reader of a philosophical or literary text had demanded of that text) are all hallmarks of a Wittgensteinian analysis.
The past few decades have seen major developments in the design and operation of cryogenic particle detectors. This technology offers an extremely good energy resolution - comparable to semiconductor ...detectors - and a wide choice of target materials, making low temperature calorimetric detectors ideal for a variety of particle physics applications. Rare event searches have continued to require ever greater exposures, which has driven them to ever larger cryogenic detectors, with the CUORE experiment being the first to reach a tonne-scale, mK-cooled, experimental mass. CUORE, designed to search for neutrinoless double beta decay, has been operational since 2017 at a temperature of about 10 mK. This result has been attained by the use of an unprecedentedly large cryogenic infrastructure called the CUORE cryostat: conceived, designed and commissioned for this purpose. In this article the main characteristics and features of the cryogenic facility developed for the CUORE experiment are highlighted. A brief introduction of the evolution of the field and of the past cryogenic facilities are given. The motivation behind the design and development of the CUORE cryogenic facility is detailed as are the steps taken toward realization, commissioning, and operation of the CUORE cryostat. The major challenges overcome by the collaboration and the solutions implemented throughout the building of the cryogenic facility will be discussed along with the potential improvements for future facilities. The success of CUORE has opened the door to a new generation of large-scale cryogenic facilities in numerous fields of science. Broader implications of the incredible feat achieved by the CUORE collaboration on the future cryogenic facilities in various fields ranging from neutrino and dark matter experiments to quantum computing will be examined.
The CUORE experiment is the world's largest bolometric experiment. The detector consists of an array of 988 TeO2 crystals, for a total mass of 742 kg. CUORE is presently taking data at the Laboratori ...Nazionali del Gran Sasso, Italy, searching for the neutrinoless double beta decay of 130Te. A large custom cryogen-free cryostat allows reaching and maintaining a base temperature of about 10 mK, required for the optimal operation of the detector. This apparatus has been designed in order to achieve a low noise environment, with minimal contribution to the radioactive background for the experiment. In this paper, we present an overview of the CUORE cryostat, together with a description of all its sub-systems, focusing on the solutions identified to satisfy the stringent requirements. We briefly illustrate the various phases of the cryostat commissioning and highlight the relevant steps and milestones achieved each time. Finally, we describe the successful cooldown of CUORE.
Pain is a symptom that should be evaluated along with its comorbidities in order to plan an effective holistic treatment strategy involving specific pharmacological interventions, side effect ...management, psychological support, control of therapeutic effects over time, and dialogue with the patient and their relatives. In this holistic process of caring for patients with pain, nurses play a central role as they deal with suffering patients directly and continuously. The purpose of this study was to evaluate the types of pain identified by nurses in their daily clinical practice and the associated comorbidities (anamnestic history taking) by geographical region and to evaluate the pharmacological strategies used.
A cross-sectional survey was performed among 696 registered nurses in Italy. Data were collected using an online questionnaire.
There was a significant difference between geographical regions in terms of reports of acute and chronic pain: acute pain was more frequently reported in the South (63.5%), while chronic pain was more frequent in the Central region (32.3%; p=0.0008). Additionally, chronic oncological pain was more frequent in the Northeast (29.6%), while chronic non-oncological pain was more frequently reported in the Central region (33.9%; p=0.0001). The underlying pain disorders reported were also different between geographical regions; rheumatic pain (21.8%) and neurological pain (18.6%) were more frequent in the Central region, while musculoskeletal pain was significantly more frequent in the South (43.4%; p=0.004). Anxiety, sleep disorders and somatization were found in acute pain (60.82%, 43.56% and 53.12%), while depression and mood disorders were more frequently detected in chronic pain condition (p<0.001).
Our study showed differences among Italian regions in pain assessment. Specific education on pain management nursing is essential for nurses. Promotion of optimal nursing care for people affected by pain is the main focus of pain management nursing. Nowadays, nurses should focus on personalized complex care and research in order to improve the patient's quality of life.
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