Characterization of electric loads provides opportunities to incorporate detailed energy usage information into applications such as protection, efficiency certification, demand response, and energy ...management. This paper proposes a low computational cost, but yet accurate method, to extract signatures for load classification and characterization. Instead of utilizing digital signal processing and frequency-domain analysis, this paper abstracts the similarity of voltage-current (V-I) trajectories between loads and proposes to map V-I trajectories to a grid of cells with binary values. Graphical signatures can then be extracted for many applications. The proposed method significantly reduces the computational cost compared with existing frequency-domain signature extraction methods. Test results show that an average of over 99% of success rate can be achieved using the proposed signatures.
The newly discovered two-dimensional materials can be used to form atomically thin and sharp van der Waals heterostructures with nearly perfect interface qualities, which can transform the science ...and technology of semiconductor heterostructures. Owing to the weak van der Waals interlayer coupling, the electronic states of participating materials remain largely unchanged. Hence, emergent properties of these structures rely on two key elements: electron transfer across the interface and interlayer coupling. Here we show, using graphene-tungsten disulfide heterostructures as an example, evidence of ultrafast and highly efficient interlayer electron transfer and strong interlayer coupling and control. We find that photocarriers injected in tungsten disulfide transfer to graphene in 1 ps and with near-unity efficiency. We also demonstrate that optical properties of tungsten disulfide can be effectively tuned by carriers in graphene. These findings illustrate basic processes required for using van der Waals heterostructures in electronics and photonics.
The emergence of smart grids has posed great challenges to traditional power system control given the multitude of new risk factors. This paper proposes an online supplementary learning controller ...(OSLC) design method to compensate the traditional power system controllers for coping with the dynamic power grid. The proposed OSLC is a supplementary controller based on approximate dynamic programming, which works alongside an existing power system controller. By introducing an action-dependent cost function as the optimization objective, the proposed OSLC is a nonidentifier-based method to provide an online optimal control adaptively as measurement data become available. The online learning of the OSLC enjoys the policy-search efficiency during policy iteration and the data efficiency of the least squares method. For the proposed OSLC, the stability of the controlled system during learning, the monotonic nature of the performance measure of the iterative supplementary controller, and the convergence of the iterative supplementary controller are proved. Furthermore, the efficacy of the proposed OSLC is demonstrated in a challenging power system frequency control problem in the presence of high penetration of wind generation.
Diabetes mellitus is a serious disease endangering human health worldwide. Vitamin D (Vit D) is a well-characterized regulator of calcium-phosphorus metabolism that also exerts other biological ...effects extending far beyond mineral homeostasis. Some epidemiological studies have suggested that Vit D has a role in defense against diabetes, although the mechanism remains unclear. Autophagy, an intracellular catabolic process, is necessary to maintain the normal structure and function of host cells. In our previous study, we found that Vit D could induce autophagy of pancreatic beta cells and prevent insulitis, although the underlying mechanisms remain to be fully elucidated. In this study, the protective effect of 1,25(OH)2D3, the physiologically active metabolite of Vit D, against streptozotocin-induced cytotoxicity in rat insulinoma cell line (INS-1) cells was explored. Cell viability and insulin secretion of INS-1 cells in response to different treatments were measured with a cell counting kit and enzyme-linked immune absorbent assay (ELISA), respectively. In addition, malondialdehyde (MDA) content and total antioxidant capacity (T-AOC) were measured by ELISA. RT-PCR and Western blot analyses were used to detect autophagy levels, reactive oxygen species (ROS) was assessed by fluorescence microscope, ultrastructure analysis was performed using transmission electron microscopy. The results demonstrated that 1,25(OH)2D3 could increase cell viability and insulin secretion of INS-1 cells, and protected cells from oxidative damage induced by streptozotocin (STZ) through autophagy activation. These findings shed light on mechanisms underlying the ameliorative effects of Vit D on diabetes mellitus.
The exciton dynamics in monolayer and bulk MoSe2 samples are studied by transient absorption microscopy with a high spatiotemporal resolution. Excitons are injected with a point-like spatial ...distribution using a tightly focused femtosecond pulse. The spatiotemporal dynamics of these excitons are monitored by measuring transient absorption of a time-delayed and spatially scanned probe pulse. We obtain the exciton diffusion coefficients of 12 ± 3 and 19 ± 2 cm(2) s(-1) and exciton lifetimes of 130 ± 20 and 210 ± 10 ps in the monolayer and bulk samples, respectively. These values are useful for understanding excitons and their interactions with the environment in these structures and potential applications of MoSe2 in optoelectronics and electronics.
Spatiotemporal dynamics of excitons in monolayer and bulk WS
2
at room temperature is studied by transient absorption microscopy in the reflection geometry. Excitons are formed from photocarriers ...injected by a tightly focused 390 nm pump pulse, and monitored by detecting different reflection of a time-delayed and spatially scanned 620 nm probe pulse. We obtain exciton lifetimes of 22 ± 1 and 110 ± 10 ps in monolayer and bulk WS
2
, respectively. Both lifetimes are independent of the exciton density, showing the absence of multi-exciton recombination processes. Exciton diffusion coefficients of 60 ± 20 and 3.5 ± 0.5 cm
2
s
−1
are obtained in monolayer and bulk samples, respectively. These results provide a foundation for understanding excitons in this new material and its optoelectronic applications.
Exciton dynamics in monolayer WS
2
investigated by spatially and temporally resolved pump-probe measurements.
Osteosarcoma is the most prevalent primary malignant bone tumor. The primary treatment for osteosarcoma is a combination of chemotherapy and surgery. However, there has been no recent progress in the ...role of chemotherapy in improving the long-term survival of osteosarcoma patients. This study aims to analyze the factors that affect chemotherapy in patients with osteosarcoma and explore the challenges and survival benefits of chemotherapy.
Patient data were downloaded from The Surveillance, Epidemiology, and End Results database. Univariable and multivariable logistic regressions were used to analyze the factors affecting patients receiving chemotherapy. Kaplan-Meier (K-M) curve was used to analyze the survival benefit of chemotherapy in patients with osteosarcoma. Finally, we used annual percentage change (APC) to evaluate the annual changes in chemotherapy treatment rates and trends in 5-year survival rates in osteosarcoma patients.
A total of 2157 osteosarcoma patients were included, of which 1887 patients received chemotherapy. Factors affecting patients receiving chemotherapy included age, primary tumor site, tumor size, N stage, M stage, and surgery. The K-M curve showed that older patients could benefit significantly from chemotherapy. The APC results showed no significant change in the chemotherapy treatment rate and 5-year overall survival rate of osteosarcoma patients.
Chemotherapy is an irreplaceable treatment for patients with osteosarcoma. However, in recent years, there has been no significant progress in chemotherapy for osteosarcoma, and the long-term survival of patients has not improved significantly. New chemotherapeutic drugs or drug delivery systems are urgently needed to improve the prognosis of patients with osteosarcoma.
Anisotropic optical and transport properties of monolayer ReS2 fabricated by mechanical exfoliation are reported. Transient absorption measurements with different polarization configurations and ...sample orientations reveal that the absorption coefficient and transient absorption are both anisotropic, with maximal and minimal values occurring when the light polarization is parallel and perpendicular to the Re atomic chains, respectively. The maximal values are about a factor of 2.5 of the minimal values. By resolving the spatiotemporal dynamics of excitons, it is found that the diffusion coefficient of excitons moving along Re atomic chains is about 16 cm2 s−1 at room temperature, which is about a factor of three larger than those moving perpendicular to that direction. An exciton lifetime of 40 ps is also extracted. These findings establish monolayer ReS2 as an anisotropic 2D transition metal dichalcogenide.
Transient absorption measurements establish monolayer ReS2 as an anisotropic 2D semiconductor. Both the linear absorption and transient nonlinear absorption are found to be a few times higher when the light polarization is along the Re atomic chain direction. Exciton diffusion is also found to be fast when moving along the Re atomic chains.