This paper discusses an analysis of the impact of tourists' food experiences at gastronomic events on destination image and these events' contribution to both destination and event loyalty. Data were ...collected with a survey conducted during two renowned Spanish gastronomic festivals: the Cherry Blossom Festival, in the Jerte Valley, and the National Cheese Fair, in Trujillo. A total of 616 valid responses were obtained and analysed using the partial least squares path modelling technique. The results show that gastronomic experiences have a positive effect on destination image and loyalty. Furthermore, destinations' structural elements have a significant relationship to destination brand but not to destination loyalty. Loyalty to gastronomic events is positively correlated with event brand and destination brand and image. Together, these elements have a positive relationship to destination loyalty. This study provides a novel approach to gastronomic experiences associated with place branding. The findings indicate that managers need to coordinate the different branding strategies of public and private administrators to focus these on emphasising the value of destinations' structural elements and events' brand and, thereby, enhancing tourists' loyalty.
This study seeks to study the relationship between market orientation and business performance and to evaluate the mediating effect of adopting a low-price strategy in this relationship in the hotel ...industry. A sample from the Spanish and Portuguese hotel industry is used. Results show that the effect of market orientation on business performance is positive and direct. On the other hand, the results do not confirm the mediating effect of a strategy based on low-price in the strength of this relationship. Moreover, results indicate that a price strategy based on low-price is negatively related to hotel business performance.
Purpose
This study aims to explore the nature of the relationship between market orientation and business performance in the Portuguese hotel industry and to evaluate the mediating role of service ...quality in this relationship.
Design/methodology/approach
A literature analysis on market orientation, service quality and hotel business performance was conducted. The structural model was developed, and the measurement scales’ items were generated. Working data were obtained by sending a survey to Portuguese hotel managers. A purification process was conducted, and the convergent and discriminant validity, as well the reliability, of the measurement models were assessed. The structural model was tested by conducting a path analysis, as well by evaluating the coefficient of determination (R2) and the predictive relevance indicator (Q2).
Findings
Research results show that market orientation has a positive direct effect on business performance. Moreover, results indicate that market orientation effects on business performance are mediated throughout the hotels’ ability to provide service quality.
Originality/value
Despite the large amount of research on market orientation, research on the hospitality sector has been conducted mainly using tools developed for the manufacturing and consumer goods sectors. On the other hand, little has been done to explore the nature of the mediating effect of service quality on the relationship between market orientation and business performance in the hotel industry. Moreover, despite the contribution of the tourism industry to the Portuguese gross domestic product, research on the hotel industry is scarce.
The clinical relevance of genetic variants in nonischemic dilated cardiomyopathy (DCM) is unsettled.
The study sought to assess the prognostic impact of disease-causing genetic variants in DCM.
...Baseline and longitudinal clinical data from 1,005 genotyped DCM probands were retrospectively collected at 20 centers. A total of 372 (37%) patients had pathogenic or likely pathogenic variants (genotype positive) and 633 (63%) were genotype negative. The primary endpoint was a composite of major adverse cardiovascular events. Secondary endpoints were end-stage heart failure (ESHF), malignant ventricular arrhythmia (MVA), and left ventricular reverse remodeling (LVRR).
After a median follow-up of 4.04 years (interquartile range: 1.70-7.50 years), the primary endpoint had occurred in 118 (31.7%) patients in the genotype-positive group and in 125 (19.8%) patients in the genotype-negative group (hazard ratio HR: 1.51; 95% confidence interval CI: 1.17-1.94; P = 0.001). ESHF occurred in 60 (16.1%) genotype-positive patients and in 55 (8.7%) genotype-negative patients (HR: 1.67; 95% CI: 1.16-2.41; P = 0.006). MVA occurred in 73 (19.6%) genotype-positive patients and in 77 (12.2%) genotype-negative patients (HR: 1.50; 95% CI: 1.09-2.07; P = 0.013). LVRR occurred in 39.6% in the genotype-positive group and in 46.2% in the genotype-negative group (P = 0.047). Among individuals with baseline left ventricular ejection fraction ≤35%, genotype-positive patients exhibited more major adverse cardiovascular events, ESHF, and MVA than their genotype-negative peers (all P < 0.02). LVRR and clinical outcomes varied depending on the underlying affected gene.
In this study, DCM patients with pathogenic or likely pathogenic variants had worse prognosis than genotype-negative individuals. Clinical course differed depending on the underlying affected gene.
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This study sought to evaluate, in the context of the commercialization strategies of tourism destinations, if investment in cultural activities such as the organization of a well-known music festival ...can promote the creation and development of the host destination's image. After a review
of the relevant literature, an analysis was done of the responses of tourists who attended the 2013 World of Music, Arts, and Dance Festival in Cáceres, Spain. The fieldwork involved a personal interview survey carried out during the event, whereby 301 valid questionnaires were obtained,
which were processed using a structural equations model and the partial least squares method. The results show how the brand positioning of a music festival can contribute to creating a positive destination image for participating tourists. The findings have significant implications for managers
in terms of music festival tourism, such as the need to emphasize the destination as a unique event setting.
Given the importance tourism has in many economies, this research was designed to study how the social and environmental benefits of Location Based Services (LBS) in the tourism sector influence user ...behavior and thus contribute to sustainable development. The objective has been to study LBS as a solution that makes the deployment of tourism activities easier, more useful and improves attitudes towards it, but in a context where trust in privacy and benefits-based sustainable social and environmental development are key. To achieve this, this research identifies what could be the influence factors in the adoption of mobile applications with Location Based Services from the point of view of the tourism sector, especially if the social and environmental benefits of LBS can help improve usage behavior. We investigated the technological acceptance of LBS in tourism, using Technology Acceptance Model (TAM) as a solid model to explain its adoption. Nine hypotheses were investigated by carrying out a survey of travelers (n = 277) during their visit to Seville (Spain). To test the conceptual model’s hypotheses, the Partial Least Squares (PLS) technique was applied to estimate variance-based structural equations models (SEM).The results of this study indicated that tourists are willing to accept these LBS services within a particular adoption model, where trust in privacy and social and environmental benefits are paramount.
Institutional environment influences the perceptions of desirability and feasibility, society’s social and cultural environment, such as beliefs, values and attitudes, conditions behaviour and ...decisions made by individuals. This research evaluates the influence of institutional environment on entrepreneurial intention using a comparative analysis of different attitudes among university students in two countries: Portugal and Spain. In particular, this study aims to examine the perceptions of desirability, feasibility and intention toward the creation of one’s own business and how that variables influence the entrepreneurial intention as compared these two different institutional contexts. Results revealed difference among attitudes toward entrepreneurship in both countries. With respect to the perception of feasibility, the majority of students in Extremadura (Spain) consider that it is easier to create a business in nowadays than it was several decades ago. However, from the students of Beira Interior (Portugal) consider that it is more difficult. Furthermore, in Extremadura, the entrepreneurial intention is higher than in Beira Interior.
•Older patients with COVID infection have a similar clinical course than younger subjects.•Males have a greater COVID mortality than females.•Worsening dyspnea and decline renal function during ...admission associate with death.•Treatment with RAAS inhibitors associates with a greater survival.
Older subjects have a higher risk of COVID-19 infection and a greater mortality. However, there is a lack of studies evaluating the characteristics of this infection at advanced age.
We studied 404 patients ≥ 75 years (mean age 85.2 ± 5.3 years, 55 % males), with PCR-confirmed COVID-19 infection, attended in two hospitals in Madrid (Spain). Patients were followed-up until they were discharged from the hospital or until death.
Symptoms started 2–7 days before admission, and consisted of fever (64 %), cough (59 %), and dyspnea (57 %). A total of 145 patients (35.9 %) died a median of 9 days after hospitalization. In logistic regression analysis, predictive factors of death were age (OR 1.086; 1.015–1.161 per year, p = 0.016), heart rate (1.040; 1.018–1.061 per beat, p < 0.0001), a decline in renal function during hospitalization (OR 7.270; 2.586–20.441, p < 0.0001) and worsening dyspnea during hospitalization (OR 73.616; 30.642–176.857, p < 0.0001). Factors predicting survival were a female sex (OR 0.271; 0.128–0.575, p = 0.001), previous treatment with RAAS inhibitors (OR 0.459; 0.222–0.949, p = 0.036), a higher oxygen saturation at admission (OR 0.901; 0.842–0.963 per percentage point increase, p = 0.002), and a greater platelet count (OR 0.995; 0.991–0.999 per 106/L, p = 0.025).
Elderly patients with COVID-19 infection have a similar clinical course to younger individuals. Previous treatment with RAAS inhibitors, and demographic, clinical and laboratory data influence prognosis.
Natural History of MYH7-Related Dilated Cardiomyopathy de Frutos, Fernando; Ochoa, Juan Pablo; Navarro-Peñalver, Marina ...
Journal of the American College of Cardiology,
10/2022, Letnik:
80, Številka:
15
Journal Article
Recenzirano
Odprti dostop
BACKGROUNDVariants in myosin heavy chain 7 (MYH7) are responsible for disease in 1% to 5% of patients with dilated cardiomyopathy (DCM); however, the clinical characteristics and natural history of ...MYH7-related DCM are poorly described. OBJECTIVESWe sought to determine the phenotype and prognosis of MYH7-related DCM. We also evaluated the influence of variant location on phenotypic expression. METHODSWe studied clinical data from 147 individuals with DCM-causing MYH7 variants (47.6% female; 35.6 ± 19.2 years) recruited from 29 international centers. RESULTSAt initial evaluation, 106 (72.1%) patients had DCM (left ventricular ejection fraction: 34.5% ± 11.7%). Median follow-up was 4.5 years (IQR: 1.7-8.0 years), and 23.7% of carriers who were initially phenotype-negative developed DCM. Phenotypic expression by 40 and 60 years was 46% and 88%, respectively, with 18 patients (16%) first diagnosed at <18 years of age. Thirty-six percent of patients with DCM met imaging criteria for LV noncompaction. During follow-up, 28% showed left ventricular reverse remodeling. Incidence of adverse cardiac events among patients with DCM at 5 years was 11.6%, with 5 (4.6%) deaths caused by end-stage heart failure (ESHF) and 5 patients (4.6%) requiring heart transplantation. The major ventricular arrhythmia rate was low (1.0% and 2.1% at 5 years in patients with DCM and in those with LVEF of ≤35%, respectively). ESHF and major ventricular arrhythmia were significantly lower compared with LMNA-related DCM and similar to DCM caused by TTN truncating variants. CONCLUSIONSMYH7-related DCM is characterized by early age of onset, high phenotypic expression, low left ventricular reverse remodeling, and frequent progression to ESHF. Heart failure complications predominate over ventricular arrhythmias, which are rare.
Destination image and loyalty development Folgado-Fernández, José A; Hernández-Mogollón, José M; Duarte, Paulo
Scandinavian journal of hospitality and tourism,
2017, Letnik:
17, Številka:
1
Journal Article
PDF
