We explored the effects of a non-traditional Master of Education Professional Development Learning Community program on its students at a mid-size Midwestern public university. Two primary questions ...in this study were: 1) Is the term transformative learning justified in describing program outcomes? and 2) To what extent did practices of our program approximate those recommended by transformative learning advocates? We solicited transformation stories from program faculty, staff, and students. Outcomes expressed were consistent with transformative learning concepts found in educational literature as were the educational environments and practices characterizing our program. Results indicated more than one-third of the stories as gains in “confidence”. The role of emotion and alternative views in transformative learning outcomes were also presented.
A critical overview of the current debate and topical thinking on international comparative investigations in mathematics education. The contributors are all major figures in international ...comparisons in mathematics. The book highlights strengths and weaknesses in various systems worldwide, allowing teachers, researchers and academics to compare and contrast different approaches. A significant contribution to the international debate on standards in mathematics.
Describes the case of a withdrawn adolescent male outpatient at a mental health clinic who was instructed to record his own verbal behavior. Consequences were implemented to increase the frequency of ...verbal responses. S "earned" his way out of the clinic by increasing his verbal behavior to an established criterion performance.
The nuclear matrix protein, NMP-2, was originally identified as an osteoblast-specific DNA-binding complex localized exclusively to the nuclear matrix. NMP-2 was shown to recognize two binding sites, ...site A (nt-605 to -599) and site B (nt -441 to -435), in the rat bone-specific osteocalcin gene promoter. This study shows that the NMP-2 binding sites A and B as well as a third NMP-2 binding site (nt -135 to -130) constitute a consensus sequence, ATGCTGGT, and represent an AML-1 recognition motif. AML-1 is a member of the AML transcription factor family which is associated with acute myelogenous leukemia and binds to the sequence TGCTGGT via its DNA-binding runt domain. Electrophoretic mobility shift assays reveal that a component of NMP-2 is a member of the AML/PEBP2/runt domain transcription factor family based on cross-competition with AML-1 consensus oligonucleotide. Limited immunoreactivity of NMP-2 with a polyclonal N-terminal AML-1 antibody and inability of the AML-1 partner protein CBF-beta to form complexes with NMP-2 indicate that NMP-2 is not identical to AML-1 but represents a variant AML/PEBP2/runt domain protein. Western and Northern blots reveal the presence of multiple AML-related proteins and AML-1 transcripts in several osseous cell lines. Furthermore, our results indicate that AML family members may selectively partition between nuclear matrix and nonmatrix compartments. Because proteins that contain a runt domain are implicated in tissue-specific transcriptional regulation, our results support the concept that the nuclear matrix mediates osteoblast-specific expression of the osteocalcin gene.
A high resolution proton magnetic resonance investigation of the hindered rotation of the dichloromethyl groups as a function of temperature in α,α,α′,α′,3,4,6-heptachloro-o-xylene (HCOX) has been ...conducted using dynamic nuclear magnetic resonance line shape analysis, supplemented with a homonuclear double resonance saturation transfer technique. The rate process in HCOX involves a coupled rotation of the two substituted methyl groups and the nonmutual exchange of the three pairs of protons between two equally populated conformers. The Arrhenius and transition state parameters were determined from the rate constants obtained over a temperature range of −5 °C to 93 °C for a 5 mol% solution of HCOX in methylcyclohexane: ΔG
≠
= 17.22 ± 0.07 kcal mol
−1
at 298 K, ΔH
≠
= 14.6 ± 0.3 kcal mol
−1
, ΔS
≠
= −8.8 ± 0.8 cal mol
−1
deg
−1
, and E
a
= 15.3 ± 0.3 kcal mol
−1
. The results obtained for HCOX are compared with those for other chloro-substituted xylenes and toluenes.
