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From the viewpoint of “diradical character,” referred to as “diradicalology,” we investigate the second hyperpolarizability γ—the molecular third‐order nonlinear optical (NLO) property—of ... one‐dimensional supermolecular systems composed of acetylene‐linked phenalenyl/pyrene rings using long‐range corrected spin‐unrestricted density functional theory. It turns out that the pyrene‐based superpolyenes (Py‐n) behave like closed‐shell systems, whereas phenalenyl‐based superpolyenes (Ph1‐n and Ph2‐n) have different diradical characters depending on the linked form, that is, Ph1‐n and Ph2‐n have intermediate and pure diradical characters, respectively. In comparison with Py‐n and Ph2‐n, the longitudinal γ of Ph1‐n is significantly larger, and it displays larger enhancement as a function of system size. Substitutions to the terminal rings by donor (NH2) and acceptor (NO2) groups further enhance γ in Ph1‐n, more than in Ph2‐n and Py‐n. These results are in agreement with the structure–property relationships derived for open‐shell NLO systems with symmetric and asymmetric charge distributions (Nakano et al., J. Chem. Phys. 2010, 133, 154302). © 2012 Wiley Periodicals, Inc. Third order non‐linear optical properties of open‐shell singlet systems are strongly correlated with their diradical characters. As such these properties can be controlled as a function of the diradical characters, a concept that it is referred to as “diradicalology”. In this work “diradicalology” is explored for a series of open‐shell superpolyene systems, composed of acetylene‐linked phenalenyl radicals. več

The patient was a 26-year-old woman who ingested a total of 230 tablets, including 160 lithium carbonate tablets (200 mg), in a suicide attempt, and was brought to our hospital 5 hr later. After ... arriving at the hospital, her only complaint was mild nausea, and no neurological abnormalities or renal dysfunction was observed. We were unable to learn the blood concentration of lithium immediately. A forced diuresis was performed after admission, but the nausea persisted. Continuous hemodialysis (CHD) was performed for 23.5 hr starting 19 hr after ingesting the tablets because the patient had ingested a large amount of lithium carbonate, 32,000 mg. Since the nausea resolved after the CHD was started and no manifestations of lithium intoxication had developed as of 91 hr after ingestion, the patient was discharged. The blood lithium concentrations (mEq/L) revealed at a later date showed that the concentration 5 hr (at the time of the initial examination), 19 hr (start of CHD), 44.5 hr (end of CHD), and 91 hr after ingestion (at the time of discharge) was 4.08, 3.30, 1.09, and 0.38, respectively. Blood purification is said to be effective in treating serious lithium intoxication, but it is difficult to judge when to stop. A favorable outcome of treatment of acute lithium intoxication in a patient with normal renal function appears to have been achieved by performing CHD guided by the clinical manifestations, intravascular redistribution times, etc. več

Case 1 : A 54-year-old man visited our hospital with the complaints of fever, nausea, and lumbago. Examinations revealed space-occupying lesions (SOLs) in the liver and a gastric submucosal tumor. ... Case 2 : A 73-year-old man presented to our hospital with the complaints of fever, dizziness, and loss of appetite. A SOL in the liver and a gastric submucosal tumor were detected. Both patients were treated with intravenous antibiotics because of suspected liver abscesses based on the clinical findings, and their symptoms and liver lesions improved. After treatment of the liver abscesses, both patients were successfully treated by laparoscopic wedge resection. Histopathology revealed a schwannoma in Case 1, and a GIST in Case 2. The liver abscesses were assumed to have been caused by the intra-gastric bacteria in the infected necrotic tissue of the submucosal tumor reaching the liver via the portal vein. As there are few reports of liver abscesses caused by gastric submucosal tumors, we report our cases with a review of the relevant literature. več

Vasohibin-1 (VASH1) is isolated as an endogenous angiogenesis inhibitor produced by the vascular endothelium. We previously reported that tumor growth and tumor angiogenesis were augmented in VASH1 ... (-/-) mice. Here we examined whether VASH1 plays any role in cancer metastasis. When Lewis lung carcinoma (LLC) cells were inoculated in the footpad to observe spontaneous metastasis, a significant increase in lung metastasis together with inguinal lymph node metastasis was evident in the VASH1 (-/-) mice. Histological analyses revealed that vessels of the footpad tumor in VASH1 (-/-) mice were more immature, having fewer mural cells. However, when LLC cells were injected into a tail vein, the extent of lung metastasis was unchanged between wild-type mice and VASH1 (-/-) mice. When VASH1 in endothelial cells in culture was knocked-down by siRNA, we observed a decrease in the content of ZO-1, a component of tight junctions, which decrease resulted in increased transmigration of cancer cells across the endothelial cell monolayer. These results indicate that endogenous VASH1 tightens the endothelial barrier and makes tumor vessels resistant to cancer metastasis. več

症例は60歳，男性．貧血の精査目的に当院に紹介された．上部消化管内視鏡にて出血性の１型胃腫瘍を認め，EMRを施行した．病理組織学的検査にて胃癌，垂直断端陽性の診断となり，追加的外科治療として胃全摘を施行した．術中，十二指腸が右腹部に下行し，小腸が右腹部に偏在していることが判明した．盲腸，上行結腸は後腹膜に固定されておらず，全結腸は正中から左腹部に存在していた．Ladd靱帯を認め，腸回転異常症と診断した．胃全摘を施行したのち，Ladd靱帯を切離した．次いで上行結腸の右側を通る経路で空腸を挙上し，R-Y再建を行った．また虫垂切除術も施行した．腸回転異常症を伴った胃癌の手術の場合，腸回転異常症に対する処置や胃切除後の再建方法などについて検討を要する．しかし同様の症例は非常に稀であり，標準的な手術方法は確立されていないため，文献的考察を加えて本症例を報告する．

症例は83歳，女性．腹痛と肝機能障害の精査目的に，当院に紹介された．精査にて胆管癌の診断となり，膵頭十二指腸切除術が施行された．門脈前面で膵を切離した後に膵頭部を門脈右側から剥離した．その際，膵鈎部が門脈の背側に延長していることが確認された．さらに剥離を左に進めると，膵鈎部は門脈左縁で膵体部に癒合することが確認された．術前CTを再検討すると指摘可能であり，門脈輪状膵と診断した．膵管は1本で門脈腹側を通過していた．膵頭部を門脈と脾静脈から剥離授動し，癒合部より左の膵体部で再切離した．これにより，通常通りの膵管空腸吻合と膵空腸密着縫合が可能になった．術後，膵瘻を合併したが保存治療で軽快し退院した．門脈輪状膵を有する患者に膵頭十二指腸切除術を施行する際は，膵の切離再建方法について検討を要する．しかし，同様の症例は非常に稀であり，標準的な手術方法は確立されていないため，文献的考察を加えて自験例を報告する．

症例1は54歳，男性．発熱，嘔気，腰痛を主訴に当院を受診した．精査にて肝占拠性病変と胃粘膜下腫瘍を指摘された．症例2は73歳，男性．発熱，めまい，食欲不振を主訴に当院を受診した．精査にて肝占拠性病変と胃粘膜下腫瘍を指摘された．両例とも臨床症状から肝膿瘍を疑い抗生物質投与を行ったところ，症状は改善し，肝病変も消失した．肝膿瘍治療後に腹腔鏡下胃局所切除術を施行し，経過は良好であった．胃粘膜下腫瘍の病理診断は症例1が神経鞘腫，症例2がGISTであった．胃内細菌がDelleから腫瘍内壊死組織に感染し，経門脈経路で肝に到達，肝膿瘍を形成したと考えられた．肝膿瘍を契機に発見された胃粘膜下腫瘍の報告は稀であり，貴重な症例と考えられたため，文献的考察を加えて報告する．

Uplink MU-MIMO techniques achieve the high frequency efficiency. However, it is known that the frequency efficiency depends on the arrangement of antennas of the access point. Moreover, we have ... proposed the distributed antenna system (DAS) which selects the high density arranged antennas according to user distribution and shown its effectiveness using narrow band signals in an actual indoor environment. For the actual implementation, this paper proposes an antenna selection methods that selects the antenna in a limited area and selects the antenna in a non-limited area. We compare the basic characteristics of the DAS when applied the uplink MU-MIMO by broadband OFDM signals in an indoor environment for each selection method, and demonstrate the effectiveness of DAS with the proposed antenna selection methods. več

This study forcuses on awareness of residents and motivation for participation in the greening community development in Ushikubonishi area in Yokohama city. We clarify how residents high motivation ... to participation in the greening community development. We verify the greening community development has effect of a community. več