Karate is a martial art that require a high level of motor and functional abilities, discipline and mental concentration as well. Practicing Kata improves self-awareness and focus, but is not always ...included in a class agenda. The author’s of sensomotor communication system based exercises have combined principles of movement from martial arts for body awareness. The purpose of this study was to examine the effects of 12 weeks intervention program of sensomotor communication system based exercises on static balance and self-esteem in karate pupils. In the study 24 karate pupils in the age of 7-12 were included. Training years in karate varied from 1 to 4 years of practice. To assess static balance the Flamingo balance test was used, to evaluate self-esteem, a modified Rosenger self-esteem scale was used. The findings of this study showed a positive effect on static balance and a minor positive effect on self-esteem in karate pupils after the intervention. Sensomotor communication system based exercises could be used for balance and self-esteem improvement. Also, being a more understandable and clearer exercise system, the sensomotor communication exercise program could be a Kata alternative for younger children practicing karate.
Atrial fibrillation (AFib) is a disease that can influence the health related quality of life. Also oral anticoagulants can influence it both because of its therapeutic benefits or complications as ...well as how the anticoagulant usage influence the person's life style by regular laboratory test necessity or diet restrictions.
Determine and analyze whether there is a statistically significant difference comparing health related quality of life between K vitamin antagonist, warfarin, users, novel anticoagulant (NOAC), rivaroxaban, dabigatran, users and patients, who do not use any kind of oral anticoagulant.
A cross-sectional analytic research was made in Pauls Stradins Clinical university hospital, Center of Cardiology in Riga, Latvia during the time period from October 2016 till June 2017. Persons with high-risk non-valvular atrial fibrillation were offered to participate in this research. If the person agreed, an oral interview with questions about disease anamnesis, demographic data, laboratory test results, echocardiography results, modified SF-36 survey, used oral anticoagulant type was held. Data were precised with the help of the case anamnesis information. For statistical data analysis was used SPSS Statistics database.
Altogether 218 patients were enrolled, of which 56.9% were female and 43.1% – male, mean age – 70.4 years, mean CHA2D2-VASc score – 4.4. Warfarin used 37.6%, 33.0% – novel oral anticoagulants, but 29.4% did not use any kind of oral anticoagulant. A statistically significant difference was discovered between the mean ranks in physical functioning sections comparing warfarin (mean rank 95.85) with NOACs (mean rank 124.57); p=0.012. Also a statistically significant difference was in social functioning comparing warfarin (mean rank 96.16) with NOACs (mean rank 119.08); p=0.026. Age had low negative correlation (r=−0.23) with physical functioning. Duration of atrial fibrillation diagnosis did not have correlations with the results.
NOAC usage correlates with the best health related quality of life scores, gaining a statistically significant difference compared to warfarin users in physical functioning (warfarin – 95.85, NOACs – 124.57; p=0.012) and social functioning mean ranks (warfarin – 95.16, NOACs – 119.08; p=0.026). Age had low negative correlation with physical functioning scores.
It was concluded that depression (D) is an independent risk factor for cardiovascular diseases (CVD), and is not related to other previously determined cardiac risk factors. Compared with ...non-depressed patients, the risk of cardiac arrest increased in less severely depressed patients. D worsens the CVD prognosis by significantly increasing the risk of recurrent coronary heart disease (CHD). Some studies suggest that OS directly increases the risk of D in patients with CVD. Oxidative stress (OS) is considered an emergency mechanism that relates to both CVD and D pathophysiology. The common risk factors increase the production of OS and reduce antioxidant defences, thereby promoting the occurrence and development of interacted ischaemic CVD and D. At present, there is insufficient evidence that routine screening of D in patients with CHD will ultimately help improve the patient’s condition. This review reiterates the need for a multidisciplinary approach, which is necessary to understand, diagnose and then treat this frequent co-morbid condition of CHD and D. Assessment of OS markers could modify risk stratification, diagnosis and prevention and treatment of patients with both CHD and D, in patients with and without previous cardiac history.
Increased excitotoxity in response to stressors leads to oxidative stress (OS) due to accumulation of excess reactive oxygen/nitrogen species. Neuronal membrane phospholipids are especially ...susceptible to oxidative damage, which alters signal transduction mechanisms. The Contingent of International Operations (CIO) has been subjected to various extreme stressors that could cause Posttraumatic Stress Disorder (PTSD). Former studies suggest that heterogeneity due to gender, race, age, nutritional condition and variable deployment factors and stressors produce challenges in studying these processes. The research aim was to assess OS levels in the PTSD risk group in CIO. In a prospective study, 143 participants who were Latvian CIO, regular personnel, males, Europeans, average age of 27.4, with the same tasks during the mission, were examined two months before and immediately after a six-month Peace Support Mission (PSM) in Afghanistan. PCL-M questionnaire, valid Latvian language "Military" version was used for PTSD evaluation. Glutathione peroxidase (GPx), superoxide dismutase (SOD) and lipid peroxidation intensity and malondialdehyde (MDA) as OS indicators in blood were determined. Data were processed using SPSS 20.0. The MDA baseline was 2.5582 μM, which after PSM increased by 24.36% (3.1815 μM). The GPx baseline was 8061.98 U/L, which after PSM decreased by 9.35% (7308.31 U/L). The SOD baseline was 1449.20 U/gHB, which after PSM increased by 2.89% (1491.03 U/gHB). The PTSD symptom severity (total PCL-M score) baseline was 22.90 points, which after PSM increased by 14.45% (26.21 points). The PTSD Prevalence rate (PR) baseline was 0.0357, which after PSM increased by 147.06% (0.0882). We conclude that there is positive correlation between increase of OS, PTSD symptoms severity level, and PTSD PR in a group of patients with risk of PTSD - CIO. PTSD PR depends on MDA intensity and OS severity. OS and increased free radical level beyond excitotoxity, is a possible causal factor for clinical manifestation of PTSD
Increased excitotoxity in response to stressors leads to oxidative stress (OS) due to accumulation of excess reactive oxygen/nitrogen species. Neuronal membrane phospholipids are especially ...susceptible to oxidative damage, which alters signal transduction mechanisms. The Contingent of International Operations (CIO) has been subjected to various extreme stressors that could cause Posttraumatic Stress Disorder (PTSD). Former studies suggest that heterogeneity due to gender, race, age, nutritional condition and variable deployment factors and stressors produce challenges in studying these processes. The research aim was to assess OS levels in the PTSD risk group in CIO. In a prospective study, 143 participants who were Latvian CIO, regular personnel, males, Europeans, average age of 27.4, with the same tasks during the mission, were examined two months before and immediately after a six-month Peace Support Mission (PSM) in Afghanistan. PCL-M questionnaire, valid Latvian language “Military” version was used for PTSD evaluation. Glutathione peroxidase (GPx), superoxide dismutase (SOD) and lipid peroxidation intensity and malondialdehyde (MDA) as OS indicators in blood were determined. Data were processed using SPSS 20.0. The MDA baseline was 2.5582 μM, which after PSM increased by 24.36% (3.1815 μM). The GPx baseline was 8061.98 U/L, which after PSM decreased by 9.35% (7308.31 U/L). The SOD baseline was 1449.20 U/gHB, which after PSM increased by 2.89% (1491.03 U/gHB). The PTSD symptom severity (total PCL-M score) baseline was 22.90 points, which after PSM increased by 14.45% (26.21 points). The PTSD Prevalence rate (PR) baseline was 0.0357, which after PSM increased by 147.06% (0.0882). We conclude that there is positive correlation between increase of OS, PTSD symptoms severity level, and PTSD PR in a group of patients with risk of PTSD - CIO. PTSD PR depends on MDA intensity and OS severity. OS and increased free radical level beyond excitotoxity, is a possible causal factor for clinical manifestation of PTSD
Paaugstināts eksaitotoksicitātes līmenis kā atbildes reakcija uz stresoriem lieka reaktīvā skābekļa/slāpekļa uzkrāšanās rezultātā izraisa oksidatīvo stresu (OS). Neironālo membrānu fosfolipīdi ir īpaši jutīgi pret oksidatīvo bojājumu, rezultātā mainot signālu pārneses mehānismu. Starptautisko operāciju kontingents (SOK) tiek pakļauts dažādiem ekstremāliem stresoriem, kas varētu izraisīt posttraumatiskā stresa sindromu (PTSS). Pieejamie pētījumu dati nav viendabīgi pēc dzimuma, rases, vecuma, uztura un dažādiem dienesta faktoriem un stresoriem, kas apgrūtina to salīdzināšanu. Pētījuma mērķis: novērtēt OS līmeni PTSS riska grupā. Pētījumā piedalījās 143 dalībnieki - Latvijas SOK. regulārais militārais personāls, vīrieši, eiropieši, kuru vidējais vecums ir 27,4 gadi, ar vienādiem uzdevumiem misijas laikā - tika izmeklēti divus mēnešus pirms un uzreiz pēc sešu mēnešu ilgas Miera uzturēšanas misijas (MUM) Afganistānā. PTSS novērtēšanai izmantota PCL-M anketa, apstiprināta latviešu valodas “militārā” versija. Asinīs noteikti OS rādītāji: glutationa peroksidāze (GPx), superoksīda dismutāze (SOD) un lipīdu peroksidāciju intensitātes rādītājs - malondialdehīds (MDA). Dati tika apstrādāti, izmantojot SPSS 20.0. MDA bāzes līmenis (2,5582 |jM) pēc MUM pieauga par 24,36% (3,1815 |jM). GPx bāzes līmenis (8061,98 U/L) pēc MUM samazinājās par 9,35% (7308,31 U/L). SOD bāzes līmenis (1449,20 U/gHB) pēc MUM palielinājās par 2,89% (1491,03 U/gHB). PTSS simptomu smaguma (PCL-M punktu skaits) bāzes līmenis bija 22,90 punkti, pēc MUM tas palielinājās par 14,45% (26,21 punkts). PTSS izplatības koeficienta (IK) bāzes līmenis bija 0,0357, pēc MUM tas pieauga par 147,06% (0,0882). Autori secina, ka pastāv pozitīva korelācija starp OS pieaugumu, PTSS simptomu smaguma pakāpes līmeni un PTSS IK pacientiem PTSS riska grupā (SOK). PTSS IK ir atkarīgs no MDA līmeņa un OS smaguma. Iespējams, ka OS un eksaitotoksicitātes rezultātā palielinātais brīvo radikāļu līmenis ir veicinošs faktors PTSS klīniskās izpausmes attīstībai.