In this trial involving women with symptomatic fibroids who were planning to undergo surgery, treatment with the selective progesterone-receptor modulator ulipristal acetate was effective in ...controlling excessive bleeding and reducing fibroid size at 13 weeks.
Uterine leiomyomas, or fibroids, are benign, hormone-sensitive, smooth-muscle tumors that occur in 20 to 40% of women of reproductive age.
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The most common symptoms are menorrhagia and iron-deficiency anemia, which may lead to chronic fatigue
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that may not be adequately controlled with iron supplementation alone.
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Other symptoms include pelvic pain, dysmenorrhea, and pressure effects, which may adversely affect quality of life and fertility.
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Many patients require intervention, and the choice of treatment is guided by the patient's age and desire to preserve fertility and avoid hysterectomy.
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Fibroids are the most common indication for hysterectomy.
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Other treatments include . . .
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