Migrants' home gardens may be created from elements of both old and new landscapes. We assume that medicinal plant assemblages in migrants' gardens are shaped by plant diversity and availability, ...therapeutic needs, and heritagization processes. Which of the factors prevail: those related to biodiversity and ecology, epidemiology, or heritage and memory? In this paper we offer new knowledge on the garden landscapes of the Global South. The research was conducted in the Atlantic Forest in Argentina. We surveyed 120 home gardens: 60 of transborder Paraguayan migrants, and 60 of transcontinental Europeans who arrived in Misiones, Argentina before WW2 and their descendants. We compared the richness, composition, medicinal uses, and the relationships of garden plants (via plant networks) between these groups, taking into account everyday scales and the transnational scale. Paraguayans cultivated and protected 137 species, predominantly native, and people of European origin 119 spp., native and exotic in similar proportions. The similarity in plant composition (68%) and the consensus in the medicinal use of plants (62%) were high between the migrant groups. Plant network analysis revealed many overlaps in assemblages of plants, but certain particularities of each group remained because of cultural expressions and therapeutic needs. This high level of similarity suggests that plant diversity, both native and allochthonous, shared concepts of illness, and the flux of knowledge between these groups was more significant than heritagization practices in shaping home gardens' medicinal plant assemblages. People of Paraguayan and European origins do not make an active effort to convert their home gardens into heritage. Medicinal plants are connected to the lived emplacement-intimate daily practices-rather than to ethnic identity strategies. Nevertheless, the plant assemblages in gardens have been shaped by ecology, colonial legacy, nostalgia, and transfer of knowledge; therefore migrants' home gardens can be considered heritage in a broad sense.
Polar biotransformation products have been identified as causative agents for the eventual increase in genotoxicity observed after the bioremediation of PAH-contaminated soils. Their further ...biodegradation has been described under certain biostimulation conditions; however, the underlying microorganisms and mechanisms remain to be elucidated. 9,10-Anthraquinone (ANTQ), a transformation product from anthracene (ANT), is the most commonly detected oxygenated PAH (oxy-PAH) in contaminated soils. Sand-in-liquid microcosms inoculated with creosote-contaminated soil revealed the existence of a specialized ANTQ degrading community, and Sphingobium sp. AntQ-1 was isolated for its ability to grow on this oxy-PAH. Combining the metabolomic, genomic, and transcriptomic analyses of strain AntQ-1, we comprehensively reconstructed the ANTQ biodegradation pathway. Novel mechanisms for polyaromatic compound degradation were revealed, involving the cleavage of the central ring catalyzed by Baeyer–Villiger monooxygenases (BVMO). Abundance of strain AntQ-1 16S rRNA and its BVMO genes in the sand-in-liquid microcosms correlated with maximum ANTQ biodegradation rates, supporting the environmental relevance of this mechanism. Our results demonstrate the existence of highly specialized microbial communities in contaminated soils responsible for processing oxy-PAHs accumulated by primary degraders. Also, they underscore the key role that BVMO may play as a detoxification mechanism to mitigate the risk posed by oxy-PAH formation during bioremediation of PAH-contaminated soils.
Background
Despite the existence of numerous published models predicting the risk of caesarean delivery in women undergoing induction of labour (IOL), validated models are scarce.
Objectives
To ...systematically review and externally assess the predictive capacity of caesarean delivery risk models in women undergoing IOL.
Search strategy
Studies published up to 15 January 2021 were identified through PubMed, CINAHL, Scopus and ClinicalTrials.gov, without temporal or language restrictions.
Selection criteria
Studies describing the derivation of new models for predicting the risk of caesarean delivery in labour induction.
Data collection and analysis
Three authors independently screened the articles and assessed the risk of bias (ROB) according to the prediction model risk of bias assessment tool (PROBAST). External validation was performed in a prospective cohort of 468 pregnancies undergoing IOL from February 2019 to August 2020. The predictive capacity of the models was assessed by creating areas under the receiver operating characteristic curve (AUCs), calibration plots and decision curve analysis (DCA).
Main results
Fifteen studies met the eligibility criteria; 12 predictive models were validated. The quality of most of the included studies was not adequate. The AUC of the models varied from 0.520 to 0.773. The three models with the best discriminative capacity were those of Levine et al. (AUC 0.773, 95% CI 0.720–0.827), Hernández et al. (AUC 0.762, 95% CI 0.715–0.809) and Rossi et al. (AUC 0.752, 95% CI 0.707–0.797).
Conclusions
Predictive capacity and methodological quality were limited; therefore, we cannot currently recommend the use of any of the models for decision making in clinical practice.
Tweetable
Predictive models that predict the risk of cesarean section in labor inductions are currently not applicable.
Tweetable
Predictive models that predict the risk of cesarean section in labor inductions are currently not applicable.
Telehealth delivery expanded quickly during the COVID-19 pandemic after the reduction of payment and regulatory barriers, but older adults are the least likely to benefit from this expansion. Little ...is known about physician experiences initiating telehealth and factors that fostered or discouraged adoption during the COVID-19 pandemic with older adult patients. Therefore, our objective was to understand experiences of frontline physicians caring for older adults via telehealth during the COVID-19 pandemic.
We conducted semi-structured interviews from September 2020 to November 2020 with 48 physicians. We recruited a diverse sample of geriatricians (n = 18), primary care (n = 15), and emergency (n = 15) physicians from all United Stated (US) regions, rural-urban settings, and academic-community practices who cared for older adult patients during the pandemic using purposive sampling methods. We completed framework analysis of the transcribed interviews to identify emerging themes and used the Quadruple Aim to organize themes.
Frontline physicians described telehealth as a more flexible, value-based, and patient-centered mode of health care delivery. Benefits of using telehealth to treat older adults included reducing deferred care and increasing timely care, improving efficiency for physicians, enhancing communication with caregivers and patients, reducing patient travel burdens, and facilitating health outreach and education. Challenges included unequal access for rural, older, or cognitively impaired patients. Physicians noted that payment parity with in-person visits, between video and telephone visits, and relaxation of restrictive regulations would enhance their ability to continue to offer telehealth.
Frontline physicians who treated older adults during the COVID-19 pandemic were largely in favor of continuing telehealth use beyond the pandemic; however, they noted that sustainability would depend on enacting policies that address access inequities and reimbursement concerns. Our data provide policy insights that if placed into action could facilitate the long-term success of telehealth and encourage a more flexible healthcare delivery system in the US.
Abstract
Background
Individuals aged 65 and older face unique barriers to adoption of telehealth, and the coronavirus disease 2019 pandemic has provided a “natural experiment” in how to meet the ...health needs of older patients remotely. Physician perspectives on practical considerations surrounding telehealth adoption, motivations of use, and reasons for nonuse are necessary to inform the future of healthcare delivery. The objective is to understand the experiences of physicians using telemedicine for older patients.
Methods
From September to November 2020, we conducted 30‐min semi‐structured interviews using purposeful sampling to identify and enroll participants from diverse settings. We included 48 U.S.‐based physicians (geriatrician,
n
= 18, primary care,
n
= 15, emergency,
n
= 15) from all geographic regions, rural–urban and academic/community settings. Audio‐recorded interviews were professionally transcribed and analyzed using framework analysis. Major themes and subthemes were identified.
Results
Participants had a median (interquartile range) age of 37.5 (34–44.5), 27 (56%) were women. Five major themes emerged: (1) telehealth uptake was rapid and iterative, (2) telehealth improved the safety of medical care, (3) use cases were specialty‐specific (for geriatricians and primary care physicians telehealth substituted for in‐person visits; for emergency physicians it primarily supplemented in‐person visits), (4) physicians altered clinical care to overcome older patient barriers to telehealth use, and (5) telehealth use among physicians declined in mid‐April 2020, due primarily to patient needs and administrator preferences, not physician factors.
Conclusion
In this qualitative analysis, physicians reported a rapid, iterative uptake of telehealth and attenuation of use as coronavirus disease 2019 prevalence declined. Physician experiences during the pandemic can inform interventions and policies to help buoy telehealth for ongoing healthcare delivery and ensure its accessibility for older Americans.
We present a 3-dimensional fully natural sonic crystal composed of spherical aggregates of fibers (called Aegagropilae) resulting from the decomposition of Posidonia Oceanica. The fiber network is ...first acoustically characterized, providing insights on this natural fiber entanglement due to turbulent flow. The Aegagropilae are then arranged on a principal cubic lattice. The band diagram and topology of this structure are analyzed, notably via Argand representation of its scattering elements. This fully natural sonic crystal exhibits excellent sound absorbing properties and thus represents a sustainable alternative that could outperform conventional acoustic materials.
Beamforming enhances the performance of array-based photoacoustic microscopy (PAM) systems for large-area scan. In this study, we quantify the imaging performance of a large field-of-view ...optical-resolution photoacoustic-microscopy system using an phased-array detector. The system combines a low-cost pulsed-laser diode with a 128-element linear ultrasound probe. Signal-to-noise ratio (SNR) and generalized contrast-to-noise ratio (gCNR) are quantified using the phased-array detector and applying three beamforming strategies: a no-beamforming method equivalent to a single-element flat transducer, a fixed focus beamforming method that mimics a single-element focused transducer, and a dynamic focus beamforming using a delay-and-sum (DAS) algorithm. The imaging capabilities of the system are demonstrated generating high-resolution images of tissue-mimicking phantoms containing sub-millimetre ink tubes and an ex vivo rabbit’s ear. The results show that dynamic focus DAS beamforming increases and homogenizes SNR along 1-cm2 images, reaching values up to 15 dB compared to an unfocused detector and up to 30 dB compared to out-of-focus regions of the fixed focus configuration. Moreover, the obtained values of gCNR using the DAS beamformer indicate an excellent target visibility, both on phantoms and ex vivo. This strategy makes it possible to scan larger surfaces compared to standard configurations using single-element detectors, paving the way for advanced array-based PAM systems.
•We designed a photoacoustic microscopy system combining a PLD with a phased array.•Beamforming increases and homogenizes SNR along large-area PAM images.•Beamforming in PAM enables physical coupling between the sample and ultrasound probe.
Staphylococcus aureus clonal complex 398 (CC398) isolates cluster into two distinct phylogenetic clades based on single-nucleotide polymorphisms (SNPs) revealing a basal human clade and a more ...derived livestock clade. The scn and tet(M) genes are strongly associated with the human and the livestock clade, respectively, due to loss and acquisition of mobile genetic elements. We present canonical single-nucleotide polymorphism (canSNP) assays that differentiate the two major host-associated S. aureus CC398 clades and a duplex PCR assay for detection of scn and tet(M). The canSNP assays correctly placed 88 S. aureus CC398 isolates from a reference collection into the human and livestock clades and the duplex PCR assay correctly identified scn and tet(M). The assays were successfully applied to a geographically diverse collection of 272 human S. aureus CC398 isolates. The simple assays described here generate signals comparable to a whole-genome phylogeny for major clade assignment and are easily integrated into S. aureus CC398 surveillance programs and epidemiological studies.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Monthly litterfall was monitored over a 3-year period in afforested Aleppo pines in the Mediterranean semiarid SE Spain with the aim of determining the long-term response of pines to reductions in ...tree competition and how this forest practice might influence stand resilience. Three thinning intensities applied 5 years earlier were evaluated (T75 = 75% of the basal area removed, T60 = 60% and T48 = 48%), both at the stand and at the tree level. On average, the total annual litterfall varied between 1.30 Mg ha−1 yr−1 (±0.24 SE) in T75 and 3.28 Mg ha−1 yr−1 (±0.78 SE) in the unthinned control. At the stand level, monthly differences among the treatments were found over time in the needles (F = 11.09, df = 3, P = 0.0009) and woody fraction (F = 4.36, df = 3, P = 0.0269) following the thinning gradient: T0 (control)>T48 > T60 > T75, and for the total amount of needles (χ2 = 9.33, P = 0.025) and twigs (χ2 = 9.11, P = 0.027) recorded at the end of the study period. High amounts of twig and needle fall were recorded during summer and beginning of autumn, whereas the main miscellanea inputs were registered during the spring, coinciding with the fall of nests and frass from caterpillar outbreaks. At the tree level, the total litterfall fluctuated between 1.5 kg tree yr−1 in T0 (2nd yr) and 7.0 kg tree yr−1 in T75 (3rd yr), although mean annual statistical differences among the treatments were found only for the first year of monitoring. However, needle fall was higher for larger pines (T75) than for the smaller ones in control (T0) when the data were analysed over the 3-year-period (F = 3.64, df = 3, P = 0.0247), and the same happened for the woody fraction (F = 3.63, df = 3, P = 0.0250). By contrast, pine trees in the unthinned control registered needle-fall rates (measured as kg m−2 tree−1) that were similar to or higher than those of pine trees in thinned stands, suggesting that defoliation processes took place at high tree densities, especially after a severely dry period. We propose thinning as a measure to adapt high-density plantations to alterations due to climate change, in order to prevent forest decline and mortality.
•The total annual litterfall varied between 1.30 Mg ha−1 yr−1 and 3.28 Mg ha−1 yr−1.•Most of the monthly litterfall was provided by needles and miscellanea.•Differences among treatments were found over time in needles and woody fractions.•At the tree level, the total litterfall fluctuated between 1.5 kg tree yr−1 and 7.0 kg tree yr−1.•Defoliation processes took place at high tree densities, especially after severely dry periods.
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