Purpose
The study aimed at investigating the state of psychiatric nurses’ job satisfaction, job burnout, and the moderating effect of family support between them in China during the COVID-19 ...pandemic.
Materials and methods
Online self-report questionnaires were distributed and 212 psychiatric nurses participated in the research. Pearson correlation analysis, multiple stepwise regression analysis, and simple slope test were used for data analysis.
Results
The results showed that the status of their job satisfaction (53.67 ± 10.72) and burnout (33.62 ± 13.84) did not reach a satisfactory level and job satisfaction had a significant negative impact on job burnout. Meanwhile, family support played a negative moderating role between the two variables.
Conclusion
Psychiatric nurses suffered from job burnout in China during the COVID-19. Family support could have a counterproductive effect when the nurses were experiencing decreasing job satisfaction. It gave suggestions to the medical institutions and the government to improve the psychological well-being of the psychiatric nurses and even of all the medical staff.
The detail and nature of earthquakes are still challenging from traditional technique observations, e.g., seismometers and strong motion accelerographs. Nowadays, the ionospheric total electron ...content (TEC) can be obtained from ground-based global navigation satellite systems (GNSS) and space-borne GNSS Radio Occultation, which can be used to investigate the seismo-ionospheric disturbances and may provide insights on the earthquake. In this paper, GNSS ionospheric seismology is presented and reviewed, including methods, observation results and characteristics. Case studies of the 2008 Wenchuan earthquake and 2011 Japan earthquake are presented using ground-based GNSS observations. Significant co-/post-seismic ionospheric anomalies are found from continuous GNSS observations near the epicenters, showing that the seismic ionospheric total electron content (TEC) disturbances were derived mainly from the main shock. The detailed pattern and evolution of the ionospheric disturbance are revealed by denser GNSS observations. Some simulations explore the nature of the ionospheric perturbation, highlighting that acoustic-gravity waves are generated close to the epicenter, and that surface Rayleigh waves and tsunamis generate in the atmosphere/ionosphere acoustic and gravity waves respectively. These waves are induced by solid-Earth/ocean and atmosphere coupling at the ground or ocean interface with the atmosphere propagating upward until the ionosphere create strong perturbation in plasma density and plasma velocity.
Study of flexible nanodielectric materials (FNDMs) with high permittivity is one of the most active academic research areas in advanced functional materials. FNDMs with excellent dielectric ...properties are demonstrated to show great promise as energy‐storage dielectric layers in high‐performance capacitors. These materials, in common, consist of nanoscale particles dispersed into a flexible polymer matrix so that both the physical/chemical characteristics of the nanoparticles and the interaction between the nanoparticles and the polymers have crucial effects on the microstructures and final properties. This review first outlines the crucial issues in the nanodielectric field and then focuses on recent remarkable research developments in the fabrication of FNDMs with special constitutents, molecular structures, and microstructures. Possible reasons for several persistent issues are analyzed and the general strategies to realize FNDMs with excellent integral properties are summarized. The review further highlights some exciting examples of these FNDMs for power‐energy‐storage applications.
Recent progress in the development of flexible nanodielectric materials (FNDMs) with high dielectric permittivity is highlighted. Particular focus is given to increasing the energy density of various FNDMs. Key issuses in the synthesis, structure, and dielectric properties of nanodielectrics are reviewed. Some long‐standing problems and topics that warrant further investigation are also addressed.
Metal sulfonate frameworks offer unique properties and enormous potential for proton conduction. This review summarizes the recent progress in this topical field, including sulfonic acid coordinated ...MOFs, sulfate groups encapsulated MOFs and the composite membranes with these MOFs and so on. In-depth disscusses of the relationship of structures and proton conducting properties on such MOFs are presented.
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•Proton conductive metal sulfonate frameworks were reviewed.•MOFs are classified and described according to the type of organic ligands.•Proton conductivity and conducting mechanism were discussed.•The future development trend of such MOFs is prospected.
Since the easy-to-design and customization of structures, guest accessibility of cavities, and functional tunability, MOFs have evolved into a burgeoning type of proton conductors. The sulfonic acid groups in MOFs can not only be used as proton sources but also can be involved in the formation of hydrogen bonds within the frameworks, which is extremely conducive to the efficient transfer of protons. In this review, recent advances of proton conductive sulfonate-based MOFs are provided covering sulfonic acid coordinated MOFs, MOFs encapsulated sulfate groups and the composite membrane contained these MOFs and so on. In-depth discussion of the relationship of structures and proton conducting properties on such MOFs is presented. Perspectives on the opportunities and challenges are proposed and highlighted.
The fast development of synthesis routes and preparation technology of 2D materials has motivated a rapid growth in the micro‐ and nanoelectronic memory devices, which gives rise to the breakthroughs ...in the semiconductor research area. Hexagon boron nitride (h‐BN) with excellent chemical, mechanical, and optical properties has been proven to have potential in overcoming the scaling limit to nanometer, and even sub‐nanometer lengths to replace the use of thick and stiff blocking dielectrics in two‐terminal or three‐terminal devices. The use of atomically thin h‐BN or h‐BN van der Waals heterostructures (vdWhs) can improve the reliability, capability, and functionality of memory devices. This is an encouraging strategy toward high‐density on‐chip integrated circuits, which has recently earned considerable interest. While the research in h‐BN material properties and characterization is comprehensively verified, specified mechanisms of resistive switching have not been analyzed in‐depth. Moreover, recent concern about novel structure design and expanding applications in electronics, optoelectronics, and spintronics has arisen. In this review, recent progress in h‐BN memories with volatile or nonvolatile properties is presented, expanding the memories to functional applications, and further challenges of the development of h‐BN‐based memories and logic circuits are discussed.
Hexagon boron nitride (h‐BN) with excellent chemical, mechanical, and optical properties has the potential to replace the use of thick and stiff blocking dielectrics in two‐terminal or three‐terminal devices. Recent progress in h‐BN memories with volatile or nonvolatile properties is presented, expanding the memories to functional applications, and further challenges in the development of h‐BN‐based memories are discussed.
In spontaneous parametric down conversion (SPDC) based quantum information processing (QIP) experiments, there is a tradeoff between the coincidence count rates (i.e. the pumping power of the SPDC), ...which limits the rate of the protocol, and the visibility of the quantum interference, which limits the quality of the protocol. This tradeoff is mainly caused by the multi-photon pair emissions from the SPDCs. In theory, the problem is how to model the experiments without truncating these multi-photon emissions while including practical imperfections. In this paper, we establish a method to theoretically simulate SPDC-based QIPs which fully incorporates the effect of multi-photon emissions and various practical imperfections. The key ingredient in our method is the application of the characteristic function formalism which has been used in continuous variable QIPs. We apply our method to three examples, the Hong-Ou-Mandel interference and the Einstein-Podolsky-Rosen interference experiments, and the concatenated entanglement swapping protocol. For the first two examples, we show that our theoretical results quantitatively agree with the recent experimental results. Also we provide the closed expressions for these interference visibilities with the full multi-photon components and various imperfections. For the last example, we provide the general theoretical form of the concatenated entanglement swapping protocol in our method and show the numerical results up to five concatenations. Our method requires only a small computational resource (a few minutes by a commercially available computer), which was not possible in the previous theoretical approach. Our method will have applications in a wide range of SPDC-based QIP protocols with high accuracy and a reasonable computational resource.
As an essential component of urban public spaces, urban streets play a crucial role in shaping cities and promoting urban sustainability. This article focuses on innovative streets as a catalyst for ...sustainable urban transition. It reviews the theoretical discussions, and empirical evidence on innovative planning approaches for urban streets. For that purpose, measures related to innovative streets are divided into two broad categories: urban mobility and urban livability. The results indicate that integrating smart street facilities with the Internet of Things (IoT), adopting a combination of grid and radial street networks, and fostering a safe street environment are vital in promoting urban mobility. Conversely, a walkable, rideable, and human-oriented street environment enhances social interaction and urban livability. The street’s dual function as a commuting and social space highlights the interplay between rising mobility and intensive street usage, leading to competition for street space. To mitigate these conflicts and advance sustainable urban transitions, enhancing street safety, reducing disparities in planning and user behavior, and accommodating the needs of all street users is crucial. Overall, the evidence supports the contribution of streets to sustainable urban transition.
The combustion phenomenon is characterized by rapid self-sustaining reactions, which can occur in the solid, liquid, or gas phase. Specific types of these reactions are used to produce valuable ...materials by different combustion synthesis (CS) routes. In this article, all three CS approaches, i.e. solid-phase, solution, and gas-phase flame, are reviewed to demonstrate their attractiveness for fabrication of zero-, one-, two-, and three-dimensional nanostructures of a large variety of inorganic compounds. The review involves five sections. First, a brief classification of combustion synthesis methods is given along with the scope of the article. Second, the state of art in the field of solid-phase combustion synthesis is described. Special attention is paid to the relationships between combustion parameters and structure/properties of the produced nanomaterials. The third and fourth sections describe details for controlling material structures through solution combustion synthesis and gas-phase flame synthesis, respectively. A variety of properties (e.g., thermal, electronic, electrochemical, and catalytic) associated with different types of CS nanoscale materials are discussed. The conclusion focuses on the most promising directions for future research in the field of advanced nanomaterial combustion synthesis.
Mitochondria play a pivotal role in the orchestration of cell death pathways. Here, we show that the control of ubiquitin dynamics at mitochondria contributes to the regulation of apoptotic cell ...death. The unique mitochondrial deubiquitylase, USP30, opposes Parkin‐dependent ubiquitylation of TOM20, and its depletion enhances depolarization‐induced cell death in Parkin‐overexpressing cells. Importantly, USP30 also regulates BAX/BAK‐dependent apoptosis, and its depletion sensitizes cancer cells to BH3‐mimetics. These results provide the first evidence for a fundamental role of USP30 in determining the threshold for mitochondrial cell death and suggest USP30 as a potential target for combinatorial anti‐cancer therapy.
Synopsis
USP30, recently described to counteract Parkin E3 ligase activity on mitochondria, is shown to regulate the mitochondrial pathway of apoptotic cell death in response to Parkin overexpression and the broadly used BH3‐mimetic therapeutic compounds.
hTERT‐RPE1‐cells stably overexpressing YFP‐Parkin undergo depolarisation‐induced, PINK1‐ and caspase‐dependent cell death, which is sensitive to proteasome but not lysosomal inhibitors.
USP30 depletion promotes Parkin‐dependent ubiquitylation of TOM20 and its subsequent degradation.
USP30 depletion enhances depolarization‐induced and Parkin‐dependent cell death.
Depletion of USP30 sensitizes RPE1, U2‐OS and MCF7 cells to BH3‐mimetics and promotes BAX/BAK‐dependent apoptotic cell death.
USP30, recently described to counteract Parkin E3 ligase activity on mitochondria, is shown to regulate the mitochondrial pathway of apoptotic cell death in response to Parkin overexpression and the broadly used BH3‐mimetic therapeutic compounds.
Colorectal cancer (CRC) has one of the highest incidences and mortality rates of all malignancies worldwide. microRNAs (miRNAs) have been reported to be involved in many biological processes of ...diseases. MiR-22-3p is considered to be involved in cancer progression, but its role in CRC remains unclear. In this study, we detected that in CRC, the level of miR-22-3p is downregulated. MiR-22-3p has antitumor effects in CRC. miR-22-3p can reduce the proliferative, invasive and migrative capacity of CRC cells. Luciferase reporter analyses confirmed that KDM3A was a target of miR-22-3p, which can directly target the 3'UTR of KDM3A and decrease the expression of KDM3A in CRC cells. Our study also confirmed that KDM3A plays a role as an oncogene in CRC. KDM3A overexpression attenuated the tumor suppressor effects of miR-22-3p in CRC cells, demonstrating that miR-22-3p exerts antitumor effects by targeting KDM3A. Overexpression of miR-22-3p in CRC reduced YAP1 expression, whereas overexpression of KDM3A restored the expression of YAP1. In summary, miR-22-3p might inhibit the progression of CRC by targeting KDM3A to regulate the HIPPO signaling pathway, which may provide an opportunity for the treatment of CRC.
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