A series of optical and one near-infrared nebular spectra covering the first year of the Type Ia supernova SN 2011fe are presented and modelled. The density profile that proved best for the early ...optical/ultraviolet spectra, "rho-11fe", was extended to lower velocities to include the regions that emit at nebular epochs. Model rho-11fe is intermediate between the fast deflagration model W7 and a low-energy delayed-detonation. Good fits to the nebular spectra are obtained if the innermost ejecta are dominated by neutron-rich, stable Fe-group species, which contribute to cooling but not to heating. The correct thermal balance can thus be reached for the strongest FeII and FeIII lines to be reproduced with the observed ratio. The 56Ni mass thus obtained is 0.47 +/- 0.05 Mo. The bulk of 56Ni has an outermost velocity of ~8500 km/s. The mass of stable iron is 0.23 +/- 0.03 Mo. Stable Ni has low abundance, ~10^{-2} Mo. This is sufficient to reproduce an observed emission line near 7400 A. A sub-Chandrasekhar explosion model with mass 1.02 Mo and no central stable Fe does not reproduce the observed line ratios. A mock model where neutron-rich Fe-group species are located above 56Ni following recent suggestions is also shown to yield spectra that are less compatible with the observations. The densities and abundances in the inner layers obtained from the nebular analysis, combined with those of the outer layers previously obtained, are used to compute a synthetic bolometric light curve, which compares favourably with the light curve of SN 2011fe.
We present a search for an electromagnetic counterpart of the gravitational wave source GW151226. Using the Pan-STARRS1 telescope we mapped out 290 square degrees in the optical i_ps filter starting ...11.5hr after the LIGO information release and lasting for a further 28 days. The first observations started 49.5hr after the time of the GW151226 detection. We typically reached sensitivity limits of i_ps = 20.3-20.8 and covered 26.5% of the LIGO probability skymap. We supplemented this with ATLAS survey data, reaching 31% of the probability region to shallower depths of m~19. We found 49 extragalactic transients (that are not obviously AGN), including a faint transient in a galaxy at 7Mpc (a luminous blue variable outburst) plus a rapidly decaying M-dwarf flare. Spectral classification of 20 other transient events showed them all to be supernovae. We found an unusual transient, PS15dpn, with an explosion date temporally coincident with GW151226 which evolved into a type Ibn supernova. The redshift of the transient is secure at z=0.1747 +/- 0.0001 and we find it unlikely to be linked, since the luminosity distance has a negligible probability of being consistent with that of GW151226. In the 290 square degrees surveyed we therefore do not find a likely counterpart. However we show that our survey strategy would be sensitive to NS-NS mergers producing kilonovae at D < 100 Mpc which is promising for future LIGO/Virgo searches.
World views of 109 white American, 67 mainland Chinese, 28 Taiwanese, and 40 Africans were investigated. White Americans differed from the other groups in the primacy given individual goals in ...interpersonal relationships and the value given the "doing" modality. Suggestions are given for a model of world views across cultures. (SLD)
We present optical and near-infrared photometric and spectroscopic observations of SN 2013ej, in galaxy M74, from 1 to 450 days after the explosion. SN 2013ej is a hydrogen-rich supernova, classified ...as a Type IIL due to its relatively fast decline following the initial peak. It has a relatively high peak luminosity (absolute magnitude M\(_\rm{V}\) = -17.6) but a small \(^{56}\)Ni production of ~0.023 M\(_\odot\). Its photospheric evolution is similar to other Type II SNe, with shallow absorption in the H{\alpha} profile typical for a Type IIL. During transition to the radioactive decay tail at ~100 days, we find the SN to grow bluer in B - V colour, in contrast to some other Type II supernovae. At late times, the bolometric light curve declined faster than expected from \(^{56}\)Co decay and we observed unusually broad and asymmetric nebular emission lines. Based on comparison of nebular emission lines most sensitive to the progenitor core mass, we find our observations are best matched to synthesized spectral models with a M\(_\rm{ZAMS}\) = 12 - 15 M\(_\odot\) progenitor. The derived mass range is similar to but not higher than the mass estimated for Type IIP progenitors. This is against the idea that Type IIL are from more massive stars. Observations are consistent with the SN having a progenitor with a relatively low-mass envelope.
We present results based on observations of SN 2015H which belongs to the small group of objects similar to SN 2002cx, otherwise known as type Iax supernovae. The availability of deep pre-explosion ...imaging allowed us to place tight constraints on the explosion epoch. Our observational campaign began approximately one day post-explosion, and extended over a period of about 150 days post maximum light, making it one of the best observed objects of this class to date. We find a peak magnitude of M\(_r\) = -17.27 \(\pm\) 0.07, and a (\(\Delta m_{15})_r\) = 0.69 \(\pm\) 0.04. Comparing our observations to synthetic spectra generated from simulations of deflagrations of Chandrasekhar mass carbon-oxygen white dwarfs, we find reasonable agreement with models of weak deflagrations that result in the ejection of ~0.2 M\(_{\odot}\) of material containing ~0.07 M\(_{\odot}\) of 56Ni. The model light curve however, evolves more rapidly than observations, suggesting that a higher ejecta mass is to be favoured. Nevertheless, empirical modelling of the pseudo-bolometric light curve suggests that \(\lesssim\)0.6 M_sun of material was ejected, implying that the white dwarf is not completely disrupted, and that a bound remnant is a likely outcome.
This study was undertaken to evaluate the effect of ketorolac (Toradol), a potent cyclooxygenase inhibitor used for postoperative pain, on microvascular thrombosis in an established thrombosis model. ...Bilateral 3-mm arterial inversion grafts (n = 66) were constructed in the femoral arteries of New Zealand White rabbits. ALZET (ALZA Corporation, Palo Alto, Calif.) osmotic pumps were implanted in the external jugular veins for drug delivery. The blinded protocol called for the experimental animals to receive intravenous doses of ketorolac of 1.72 mg/kg per day (group 1) or 3.44 mg/kg per day (group 2), while control animals received equivalent volumes of saline. Patency was assessed at 7 days.Whereas 52 percent (13 of 25) of control vessels remained patent, 70 percent (14 of 20) and 86 percent (18 of 21) of group 1 and group 2 vessels, respectively, were patent at 1 week. This decrease in microvascular thrombosis with delivery of ketorolac was statistically significant (p = 0.0094).Ketorolac, at experimental doses approximating 9 and 18 mg IV q6h in a 70-kg man, demonstrated a statistically significant reduction in microvascular thrombosis. This study supports its use in clinical microvascular surgery.
We analyse spectroscopic measurements of 122 type Ia supernovae (SNe Ia) with z<0.09 discovered by the Palomar Transient Factory, focusing on the properties of the Si II 6355 and Ca II `near-infrared ...triplet' absorptions. We examine the velocities of the photospheric Si II 6355, and the velocities and strengths of the photospheric and high-velocity Ca II, in the context of the stellar mass (Mstellar) and star-formation rate (SFR) of the SN host galaxies, as well as the position of the SN within its host. We find that SNe Ia with faster Si II 6355 tend to explode in more massive galaxies, with the highest velocity events only occuring in galaxies with Mstellar > 3*10^9 solar mass. We also find some evidence that these highest velocity SNe Ia explode in the inner regions of their host galaxies, similar to the study of Wang et al. (2013), although the trend is not as significant in our data. We show that these trends are consistent with some SN Ia spectral models, if the host galaxy stellar mass is interpreted as a proxy for host galaxy metallicity. We study the strength of the high-velocity component of the Ca II near-IR absorption, and show that SNe Ia with stronger high-velocity components relative to photospheric components are hosted by galaxies with low stellar mass, blue colour, and a high sSFR. Such SNe are therefore likely to arise from the youngest progenitor systems. This argues against a pure orientation effect being responsible for high-velocity features in SN Ia spectra and, when combined with other studies, is consistent with a scenario where high-velocity features are related to an interaction between the SN ejecta and circumstellar medium (CSM) local to the SN.
Cigarette smoking and plasma nortriptyline levels Norman, Trevor R.; Burrows, Graham D.; Maguire, Kay P. ...
Clinical pharmacology and therapeutics,
April 1977, Letnik:
21, Številka:
4
Journal Article
Recenzirano
Cigarette smoking was found to have no effect on the steady‐state plasma levels of nortriptyline in a group of 22 smokers and 31 nonsmokers. Smokers achieved a mean steady‐state nortriptyline ...concentration oi 191.2 ± 141.3 ng/ml; nonsmokers had a level of 169.3 ± 92.4 ng/ml. Age, sex, and number of cigarettes smoked had no effect on the plasma concentrations achieved.
