Nipah virus infection with cerebellar dysfunction Pallivalappil, Bhargavan; Karadan, Ummer; Chellenton, Jayakrishnan ...
European Journal of Medical Case Reports,
2020, Letnik:
4, Številka:
1
Journal Article
Background: The Nipah virus (NiV), known to exist in various fruit bats, is associated with one of the deadliest infections affecting human beings. The virus has caused outbreaks in Malaysia, ...Singapore, Philippines, Bangladesh, and the West Bengal state of India. Pigs were the intermediate hosts during the Malaysian and Singaporean outbreaks and horses in Philippines; while the Indian and Bangladesh outbreaks saw a bat to human followed by human-to-human transmission. The infection is characterized by rapidly progressive encephalitis and acute respiratory distress syndrome, carrying a very high mortality rate.
Case Presentation: We present the case of a middle-aged male who presented with fever, vomiting and loose stools, and throat pain. His initial blood investigations were normal. He later developed diplopia, cerebellar symptoms, and segmental sweating. His blood, urine, and throat swab tested positive for NiV. He was started on antivirals but succumbed to death.
Conclusion: NiV infection, in humans, presents with a wide spectrum of clinical manifestations, ranging from asymptomatic infection to acute respiratory infection and fatal encephalitis. It is transmitted to humans from animals, such as bats or pigs, or contaminated foods. This was our first experience with NiV; and probably one of the first reported cases from our region. Our experience showed the occurrence of cerebellar symptoms in NiV infection.
Hypocalcemic Seizure Due to Vitamin D Deficiency Manappallil, Robin G; Krishnan, Raghuram; Veetil, Pradeep P ...
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine,
09/2020, Letnik:
24, Številka:
9
Report
AIMTo emphasize the importance of vitamin D supplementation. BACKGROUNDThe incidence of vitamin D deficiency has been increasing worldwide, probably due to decreased exposure to sunlight and ...unbalanced diet. Severe hypocalcemia following vitamin D deficiency is rather uncommon, and this leading to seizures in adults is a rare scenario. CASE DESCRIPTIONThis is the case of a 70-year-old female, a known case of coronary artery disease, who presented with one episode of seizure. Computed tomography of her brain revealed diffuse age-related atrophic changes, and electroencephalogram showed diffuse cerebral dysfunction. She was found to have severe hypocalcemia with secondary hyperparathyroidism due to vitamin D deficiency. Vitamin D bolus was given along with calcium correction, following which she improved. CONCLUSIONThere are a few reports of hypocalcemic seizures among children; however, the incidence is rare among adults. Calcium and vitamin D supplementation forms the mainstay of treatment. CLINICAL SIGNIFICANCEHypocalcemic seizure is uncommon, especially among adults. Vitamin D deficiency resulting in hypocalcemic seizure, to the best of our knowledge, is an unreported scenario. This case highlights the importance of vitamin D supplementation in those with reduced sunlight exposure. HOW TO CITE THIS ARTICLEManappallil RG, Krishnan R, Veetil PP, Nambiar H, Karadan U, Anil R, et al. Hypocalcemic Seizure Due to Vitamin D Deficiency. Indian J Crit Care Med 2020;24(9):882-884.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
PDF