Our aim was to apply high-performance liquid chromatography method for quantitative evaluation of the total amount of sparfloxacin (SPA) immobilized on the surface of the antimicrobial urological ...catheters. The amounts of SPA bound to catheter were determined indirectly on the basis
of the differences in SPA concentrations before and after the immobilization process (they have been shown to vary from 0.11 to 5.66 mg/g of catheter). We estimated the immobilization yield, which altered from 14% to 70% depending on the SPA concentration used. As in vitro release studies
show, the antibiotic binds to the catheter matrix in two modes: relatively stable covalent bond and weak non-covalent bond. Antibacterial activity of the modified catheter samples with SPA was controlled by using the zone of inhibition test against gram positive and gram negative bacteria.
Purpose: The purpose of the article is to present the design and fabrication methodology
of metallic scaffolds, with the shape and dimensions defined by the designer, coated with a
thin layer of ...polymer.
Design/methodology/approach: The methodology proposed covers Computer Aided
Materials Design (CAMD), fabrication of metallic scaffolds using a machine for Selective
Laser Melting (SLM), the deposition of a thin layer of polymers onto scaffolds using coldwork
and hot-work polymerisers, as well as mechanical finishing. The strength of the newly
developed metal-polymer composites to three-point bending was examined and their
fractures were viewed with SEM.
Findings: A fabrication method of implants in the form of scaffolds coated with a thin layer
of polymer with the dimensions and shape closely matching the losses in a patient’s hard
and/or soft palate.
Practical implications: After clinical tests, a metal-polymer implant may be a very
beneficial alternative for patients with palate losses using traditional prostheses until now.
Originality/value: The individualised implants of palate pieces in the form of scaffolds
coated with a thin layer of polymer, submitted for patent protection, do not have their
counterparts, which is representing their originality.
The objective of the studies was evaluation of the level of magnesium in children hospitalized for severe respiratory infections (mainly pneumonia and bronchitis). The criterion for the evaluation of ...the magnesium level in the serum of the children hospitalized for severe respiratory infections were the following parameters: general condition of the child at the time of admittance, feeding pattern and psychosomatic development in the children with respiratory infection. The level of magnesium in the serum of the children admitted with median general condition was higher than that of the children admitted with poor general condition. The level of magnesium in the serum of breastfed children and those with correct psychosomatic development was higher than the level of magnesium in children fed artificially and representing backward psychosomatic development.
Photon statistics of stimulated Raman scattering of squeezed light are considered including additive noise. The phonon system is assumed to be in chaotic or squeezed chaotic states. The influence of ...nonlinear dynamics is established on the initial non-classical features of light adopting quasi-distribution related to anti-normal ordering, photocount distribution, its factorial moments and principal squeezing parameter. It is shown that the initial non-classical effects are increased by the nonlinear dynamics provided that the Stokes mode is less amplified than the anti-Stokes mode is damped, whereas in the opposite case the non-classical effects are swiftly smoothed out. The frequency detuning can be optimized to have maximum non-classical effects, which can periodically return. However, above a certain bound the non-classical effects are missing with frequency detuning, and also with increasing phonon number, even if the phonon system is squeezed. Small initial squeezing can be increased by the nonlinear dynamics, whereas strong squeezing can only be diminished.
Physiological properties of magnesium (Mg) as a catalyst of enzymatic processes mainly are known quite well. Still unclear, however, are the changes in its concentrations in the body that occur in ...the course of many diseases, among others in babies with bronchial obstructive bronchitis and pneumonia. Therefore research was undertaken to determine the concentrations of magnesium in blood serum, erythrocytes and urine in babies suffering from pneumonia (54 babies) and bronchial obstructive bronchitis (46 babies). The results found that magnesium concentrations in the blood serum, erythrocytes and urine differ significantly in the groups of sick and healthy babies. Compared to the control group significantly lowest Mg concentrations in the blood serum, erythrocytes and highest in the urine were found both before and after the treatment in the babies suffering from bronchial obstructive bronchitis.
A two-fold generalization of results concerning the third-order nonlinear dissipative oscillator is presented. The exact solution to the master equation for an arbitrary initial state is given, and ...closed formulae for the squeeze variances in the case of initial Gaussian pure and mixed states are derived.
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