Immune defences often trade off with other life-history components. Within species, optimal allocation to immunity may differ between the sexes or between alternative life-history strategies. ...White-throated sparrows (Zonotrichia albicollis) are unusual in having two discrete plumage morphs, white-striped and tan-striped. Within each sex, white-striped individuals are more aggressive and provide less parental care than tan-striped individuals. We extended immunocompetence handicap models, which predict sex differences in immunity and parasitism, to hypothesize that infection susceptibility should be greater in white-striped than tan-striped birds. We inoculated birds of both morphs with malarial parasites. Contrary to our prediction, among birds that became infected, parasite loads were higher in tan-striped than white-striped individuals and did not differ between the sexes. Circulating androgen levels did not differ between morphs but were higher in males than females. Our findings are not consistent with androgen-mediated immunosuppression. Instead, morph differences in immunity could reflect social interactions or life-history-related differences in risk of injury, and/or genetic factors. Although plumage and behavioural morphs of white-throated sparrow may differ in disease resistance, these differences do not parallel sex differences that have been reported in animals, and do not appear to be mediated by differences in androgen levels.
We briefly review an existing model of the structure of reconnection layers which predicts that several more distinct layers, in the form of contact discontinuities, rotational Alfvèn waves, or slow ...shocks, should be identifiable in solar wind reconnection events than are typically reported in studies of reconnection outflows associated with bifurcated current sheets. We re-examine this notion and recast the identification of such layers in terms of the changes associated with the boundaries of both the ion and electron outflows from the reconnection current layers. We then present a case study using Solar Orbiter MAG and SWA data, which provides evidence consistent with this picture of extended multiple layers around the bifurcated current sheet. A full confirmation of this picture requires more detailed examination of the particle distributions in this and other events. However, we believe this concept is a valuable framework for considering the nature of reconnection layers in the solar wind.
To investigate the asymptotic giant branch (AGB) population in the Galactic halo, we search for pulsating AGB stars at a heliocentric distance
D
> 50 kpc. Our research is based on the Catalina ...Southern Survey (CSS) catalogue of variables, comprising 1286 long-period variables (LPVs) with
δ
< −20°. We first focus on the 77 stars in the cap |
b
| > 30° for which spectral M-type or C-type classification can be derived from Hamburg-ESO objective prism spectra. Most of these are oxygen-rich (M-type) and very few are carbon rich. The periods are in the range 100–500 days, and CSS amplitudes are up to 3 mag. In this small sample, no halo AGB star is fainter than
K
s
0
= 12.5. This may be due to the scarcity of AGBs in the outer halo, or insufficient instrumental depth. Leaving aside spectral information, we then searched for even fainter pulsators (
K
s
> 12.5) in the entire CSS catalogue.
G
a
i
a
astrometry makes it possible to identify some contaminants. Our final result is the identification of ten candidate distant LPVs. If these ten stars obey the fundamental mode
K
-band period–luminosity relation used for Miras and small-amplitude Miras, their distances are between 50 and 120 kpc from the Sun. In a diagram showing distance versus
Gaia
tangential velocity, these ten stars have positions consistent with that of other objects in the halo, such as globular clusters and dwarf galaxies. We detect some underluminous AGBs that deserve further study. Finally, the halo LPVs ressemble the slow redder variable of globular clusters when colour and periods are compared.
BACKGROUND:High BMI is often used as a proxy for obesity and has been considered a risk factor for the development of an incisional hernia after abdominal surgery. However, BMI does not accurately ...reflect fat distribution.
OBJECTIVE:The purpose of this work was to investigate the relationship among different obesity measurements and the risk of incisional hernia.
DESIGN:This was a retrospective cohort study.
SETTINGS:The study included a single academic institution in New York from 2003 to 2010.
PATIENTS:The study consists of 193 patients who underwent colorectal cancer resection.
MAIN OUTCOME MEASURES:Preoperative CT scans were used to measure visceral fat volume, subcutaneous fat volume, total fat volume, and waist circumference. A diagnosis of incisional hernia was made either through physical examination in medical chart documentation or CT scan.
RESULTS:Forty-one patients (21.2%) developed an incisional hernia. The median time to hernia was 12.4 months. After adjusting for patient and surgical characteristics using Cox regression analysis, visceral obesity (HR 2.04, 95% CI 1.07–3.91) and history of an inguinal hernia (HR 2.40, 95% CI 1.09–5.25) were significant risk factors for incisional hernia. Laparoscopic resection using a transverse extraction site led to a >75% reduction in the risk of incisional hernia (HR 0.23, 95% CI 0.07–0.76). BMI > 30 kg/m was not significantly associated with incisional hernia development.
LIMITATIONS:Limitations include the retrospective design without standardized follow-up to detect hernias and the small sample size attributed to inadequate or unavailable CT scans.
CONCLUSIONS:Visceral obesity, history of inguinal hernia, and location of specimen extraction site are significantly associated with the development of an incisional hernia, whereas BMI is poorly associated with hernia development. These findings suggest that a lateral transverse location is the incision site of choice and that new strategies, such as prophylactic mesh placement, should be considered in viscerally obese patients.
Migratory animals encounter multiple parasite communities, raising concerns that migration may aid transport of infectious disease. How migration affects disease spread depends fundamentally on how ...disease affects migration, specifically whether infection alters individuals’ migratory physiology and behavior. We inoculated white-throated sparrows (Zonotrichia albicollis) with avian malaria parasites (Plasmodium sp.), monitored parasite loads for 5 wk as the birds reached spring migratory condition, and compared nocturnal migratory restlessness (Zugunruhe), body composition (fat, lean, and whole-body mass), and hematocrit among experimentally infected birds, sham-inoculated birds, and birds that were exposed to parasites but resisted infection. Migratory restlessness increased over time in the study, but the rate of change varied between sham (control) birds, infected birds, and birds that resisted infection. We were unable to detect any effects of malaria exposure on body condition. Our findings suggest that encountering parasites affects migratory activity, regardless of whether infection occurs or is resisted.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
56.
Ocean fertilization: a potential means of geoengineering? Lampitt, R.S; Achterberg, E.P; Anderson, T.R ...
Philosophical transactions - Royal Society. Mathematical, Physical and engineering sciences/Philosophical transactions - Royal Society. Mathematical, physical and engineering sciences,
11/2008, Letnik:
366, Številka:
1882
Journal Article
Recenzirano
Odprti dostop
The oceans sequester carbon from the atmosphere partly as a result of biological productivity. Over much of the ocean surface, this productivity is limited by essential nutrients and we discuss ...whether it is likely that sequestration can be enhanced by supplying limiting nutrients. Various methods of supply have been suggested and we discuss the efficacy of each and the potential side effects that may develop as a result. Our conclusion is that these methods have the potential to enhance sequestration but that the current level of knowledge from the observations and modelling carried out to date does not provide a sound foundation on which to make clear predictions or recommendations. For ocean fertilization to become a viable option to sequester CO2, we need more extensive and targeted fieldwork and better mathematical models of ocean biogeochemical processes. Models are needed both to interpret field observations and to make reliable predictions about the side effects of large-scale fertilization. They would also be an essential tool with which to verify that sequestration has effectively taken place. There is considerable urgency to address climate change mitigation and this demands that new fieldwork plans are developed rapidly. In contrast to previous experiments, these must focus on the specific objective which is to assess the possibilities of CO2 sequestration through fertilization.
The biomass distributions of marine benthic metazoans (meio- to macro-fauna, 1 μg-32 mg wet weight) across three contrasting sites were investigated to test the hypothesis that allometry can ...consistently explain observed trends in biomass spectra. Biomass (and abundance) size spectra were determined from observations made at the Faroe-Shetland Channel (FSC) in the Northeast Atlantic (water depth 1600 m), the Fladen Ground (FG) in the North Sea (150 m), and the hypoxic Oman Margin (OM) in the Arabian Sea (500 m). Observed biomass increased with body size as a power law at FG (scaling exponent, b = 0.16) and FSC (b = 0.32), but less convincingly at OM (b = 0.12 but not significantly different from 0). A simple model was constructed to represent the same 16 metazoan size classes used for the observed spectra, all reliant on a common detrital food pool, and allowing the three key processes of ingestion, respiration and mortality to scale with body size. A micro-genetic algorithm was used to fit the model to observations at the sites. The model accurately reproduces the observed scaling without needing to include the effects of local influences such as hypoxia. Our results suggest that the size-scaling of mortality and ingestion are dominant factors determining the distribution of biomass across the meio- to macrofaunal size range in contrasting marine sediment communities. Both the observations and the model results are broadly in agreement with the "metabolic theory of ecology" in predicting a quarter power scaling of biomass across geometric body size classes.
Flow diversion has become an established treatment option for challenging intracranial aneurysms. The use of small devices of ≤3-mm diameter remains unapproved by major regulatory bodies. A ...retrospective review of patients treated with Pipeline Embolization Devices of ≤3-mm diameter at 3 Canadian institutions was conducted. Clinical and radiologic follow-up data were collected and reported. Twelve cases were treated with ≥1 Pipeline Embolization Device of ≤3-mm diameter, including 2 with adjunctive coiling, with a median follow-up of 18 months (range, 4-42 months). One patient experienced a posttreatment minor complication (8%) due to an embolic infarct. No posttreatment hemorrhage or delayed complications such as in-stent stenosis/thrombosis were observed. Radiologic occlusion was seen in 9/12 cases (75%) and near-occlusion in 2/12 cases (17%). Intracranial aneurysm treatment with small-diameter flow-diverting stents provided safe and effective aneurysm closure in this small selected sample. These devices should be further studied and considered for regulatory approval.
Low-enriched uranium-10 wt.% molybdenum (LEU-10wt.%Mo) is of interest for the fabrication of monolithic fuels to replace highly-enriched uranium (HEU) dispersion fuels in high performance research ...and test reactors around the world. In this work, depleted uranium-10 wt.%Mo (DU-10wt.%Mo) is used to simulate the solidification and microstructural evolution of LEU-10wt.%Mo. Electron backscatter diffraction (EBSD) and complementary electron probe microanalysis (EPMA) reveal significant microsegregation present in the metastable γ-phase after solidification. Homogenization is performed at 800 and 1000 °C for times ranging from 1 to 32 h to explore the time–temperature combinations that will reduce the extent of microsegregation, as regions of higher and lower Mo content may influence local mechanical properties and provide preferred regions for γ-phase decomposition. We show for the first time that EBSD can be used to qualitatively assess microstructural evolution in DU-10wt.%Mo after homogenization treatments. Complementary EPMA is used to quantitatively confirm this finding. Homogenization at 1000 °C for 2–4 h may the regions that contain 8 wt.% Mo or lower, whereas homogenization at 1000 °C for longer than 8 h effectively saturates Mo chemical homogeneity, but results in substantial grain growth. The appropriate homogenization time will depend upon additional microstructural considerations, such as grain growth and intended subsequent processing. Higher carbon LEU-10wt.%Mo generally contains more inclusions within the grains and at grain boundaries after solidification. The effect of these inclusions on microstructural evolution (e.g. grain growth) during homogenization and as potential γ-phase decomposition nucleation sites is unclear, but likely requires additional study.
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