The pharmaceutical research sector’s inability to develop new drugs has made it challenging to combat microbial resistance. Secondary metabolites from plant extracts have been identified as potential ...protective agents against multi-drug-resistant bacteria. This study aimed to analyze hydro-ethanol extracts’ antioxidant and antimicrobial activities from various parts of the Zahidi date (whole fruit, pit powder, and flesh). Phytochemical screening of phenolic and flavonoid compounds was performed using high-performance liquid chromatography (HPLC). Total phenolic and flavonoid compounds were extracted at their maximum levels, 71.89 mg/100 g and 843.06 mg/100 g, respectively, using EoH 60%. The whole fruit had the highest concentration of flavonoid quercetin (0.83 μg/g) and phenolic compoundsinapic acid (20.03 μg/g) at the same concentration. The findings from the broth micro-dilution method showed that the whole fruit had the strongest antimicrobial effects at 60% EoHagainst Salmonella typhi (30 mg/ml), Helicobacter pylori (27 mg/ml), Escherichia coli (22 mg/ml), and Staphylococcus aureus (44 mg/ml). Zahidi whole fruit extracts showed higher antioxidant potential at EoH 60% using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) scavenging potential (78%) and ferric-reducing antioxidant power. Principal component analysis (PCA) revealed a significant negative correlation between antioxidant activity and the minimum inhibitory concentration (MIC). Evidence from this study highlights the considerable antioxidant and antimicrobial properties of Zahidi date fruit, suggesting its potential use in producing natural drugs and value-added foods to counteract contagious diseases.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
ABSTRACT Kosovo, like the global trend, is experiencing a rising demand for eggs, emphasizing the necessity for stringent regulatory oversight to maintain freshness and meet ...increasing consumer and industrials’ needs. The research aimed to evaluate the compliance of eggs in the local market with specified quality criteria outlined in the local Administrative Directive and EC Regulation. Several quality parameters were scrutinized, including egg weight, length, width, specific gravity, air cell, Haugh units (HU), yolk and egg white weights, yolk color intensity, shell weight, and shell thickness. Key parameters varied significantly among Fresh Eggs and farms F1 to F5. Most groups displayed significantly lower egg weights, yolk, and egg white weights compared to Fresh Eggs (p < 0.01). Among different groups, Fresh Eggs have the highest Haugh unit and the lowest specific gravity, indicating superior egg quality. Among groups, F4 has the lowest Haugh unit (p < 0.00001), and F3/F4 exhibited the largest air cell size (p < 0.0001), while F5/Fresh Eggs were the smallest, with no significant differences between themselves (p > 0.05). Fresh eggs outshined in all groups in relation to size and yolk color (p < 0.0001). The study found positive correlations (p < 0.01) between egg weight and internal parameters, including yolk and white weights. Eggshell weight also correlated positively with yolk and white weights (p < 0.05). Conversely, Haugh unit and air cell exhibited negative correlations (p < 0.01), indicating their influence on egg dimensions. Classification based on regulation revealed distinct categories for consumption and industrial use. These findings contribute valuable insights to Kosovo’s egg market, impacting standards and promoting fair competition.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
ABSTRACTAscorbic acid (vitamin C) is the most crucial antioxidant for the body. The biochemical capabilities of ascorbic acid are still being studied. It acts as a cofactor for many enzymes ...participating in various physiological functions. This review presents how ascorbic acid is a cofactor for multiple enzymes involved in numerous human activities. Ascorbic acid protects the immune system, reduces allergic reaction severity and assists the fight against infections and other disorders. Ascorbic acid is metabolized by several procedures in the gastrointestinal tract. Eukaryotes produce ascorbic acid via L-galactose (L-Gal) and GDP-D-mannose as part of its metabolic process. It is disseminated throughout the body cells after being readily absorbed by the digestive system. This review will uncover ascorbic acid’s biological functions and metabolism in humans.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
The current review is informed about the effectiveness of plant-derived functional components that aids in the regulation and health of endocrine glands. The endocrine glands include the thyroid, ...adrenal, hypothalamus, pituitary and pineal, ovaries and testes that play vital functions in our body such as growth and development, metabolism, mood and reproduction controlled by hormones. The abnormalities in the functions of endocrine glands are formed various disorders, some major disorders are diabetes, goiter, kidney problem, brain-related diseases and PCOS. Different parts of plant-based foods (fruits, vegetables, cereals, beans, legumes, herbs and spices) are composed of vitamins, minerals, antioxidants and phenolic compounds that help support different body functions. It is concluded that plant-based foods are a rich source of functional components that play a valuable role in regulating the function of the endocrine glands.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Kalanchoe pinnata (Lam.) Pers. is an ethnomedicinal plant known for its antioxidant, antibacterial, and therapeutic potential. The current study was an effort to explore the impact of extraction ...technique on the phytochemical, antioxidant, and antibacterial profile of the plant extracts. K. pinnata leaf extracts were prepared using conventional solvent extraction (100% methanol; 50% methanol: 50% water; 100% water), microwave-assisted extraction at 700-W power (3 min; 6 min; 9 min), and supercritical fluid extraction (SFE) (3500 psi; 4500 psi; 5500 psi). Best results were attained from SFE in terms of total phenolic content (240 ± 3 mg GAE/g), total flavonoid content (165.2 ± 0.4 mg QE/g), 2,2-diphenyl-1-picrylhydrazyl radical scavenging potential (91.9 ± 0.4%), 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulfonic acid assay value (8.04 ± 0.03 mMol TE/g) and ferric reducing antioxidant power assay value (471.7 ± 0.8 µg/mL). K. pinnata leaf extracts have been found to be most effective against Yersinia pseudotuberculosis (22.20 ± 0.95 mm) and least effective againstProteus vulgaris (0 ± 0 mm). High-performance liquid chromatography analysis of K. pinnata extract showed that it contains flavanol quercetin (2.0 ± 0.1 mg/g). It is evident from the findings of current study that K. pinnata extract can effectively treat bacterial infections and can cure metabolic disorders by reducing oxidative stress. Application of advance extraction techniques enhances the biological activity of plant extracts.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
This review discusses the chemical composition of radish pods and their utilization and health perspective. Radish pods are green vegetables usually consumed in East Asia. Radish pods have gained ...much interest due to their high chemical composition and antioxidant activity. They contain various chemical compounds, including coumarins, phenols glucosinolates, antioxidants etc. In East Asia, radish pods are usually consumed in households and can also be used commercially as an additive ingredient. However, it can be used in the household as a vegetable, mixed vegetable and additive materials. Radish pods play an important role against cancer, hypertension, cardiovascular diseases, inflammation, and allergies via diverse pathways. It also acts as a hepatoprotective, platelet aggregation and immunity booster. Hence, the radish pods can be used in households for improvement of chronic disorders.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Plums are the ubiquitous fruit belonging to genus Prunus, subgenus Prunus, consumed as food and have many health benefits and medicinal effect in the treatment of many diseases. Pulp from plums is ...also used in different beverages. Plums are the potential source of polyphenolic compounds and bioactive compounds such as phenolic, anthocyanins, and carotenoids and many organic acids such as citric acid and malic acid. Plums are also the abundant sources of many minerals such as calcium, magnesium, phosphorus, potassium, and vitamins A, B, K, and C. Plums are the abundant sources of predominant antioxidants and phenolic compounds such as caffeic acid, chlorogenic acid, crypto-chlorogenic acid, and neo-chlorogenic acid. These antioxidants and bioactive compounds are effective in the treatment and prevention of gastrointestinal diseases, bone heath, and cardiovascular diseases and in maintaining the blood glucose level. Plums helps in the heart diseases prevention, as it is low in fat content and high in dietary fiber. It is also effective in the treatment of lung and oral cancer. The consumption of plums boosts human health and prevents many diseases. The review discusses the importance, production, different varieties of plums along with its nutritional profile, availability of bioactive compounds, phytochemical composition, and antioxidants mainly phenolic and flavonoid compounds. It also introduces the beneficial effect of the bioactive compounds in heart, lungs, and cardiovascular diseases, followed by its in vivo human and animal studies.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Meat is the richest source of protein and according to meat sources, the protein is composed of different types of amino acids which are completely dependent upon the protein types. Myofibril is ...basically muscle protein that’s widely present in different types of fish and low quantity is present in different meat (camel). Myofibril is made up of thick and thin myofilaments chemically. Actin, tropomyosin, troponin, and tropomyosin are thin myofilaments on the other hand myosin is only the thick myofilament. It is helpful in the formation of strong skeleton muscle and can also stronger and formation the cardiac layers (epicardium, myocardium and endocardium). Technologically, it can be used in the formation of different food products for the purpose of developing diet supplements. This review discussed different sources and chemical properties of myofibril protein and also its potential role toward the cardiac health. Myofibril’s thick and thin filaments contribute in the construction of skeletal muscle and enhance the heart’s protective coverings. The literature has been collected from Science Direct, Google Scholar and Web of Science. Myofibrils are made up of thick and thin filaments that can help in different human body functions. In the future, more research is necessary that discuss the close relation between myofibril protein and cardiac layers.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Non-thermal processing has been developed to increase the quality and storage life of fruit juices in response to consumer desire. Ozonation is a recently developed method that generates volatile ...oxygen atoms that can eliminate a broad spectrum of microbes and extend the shelf stability of food products. The present research was intended to investigate the ozone processing on the physicochemical characteristics, microbiological quality, sensory attributes, and antioxidant potential of Kinnow juice. In this study, Kinnow juice was processed to 150 mg/h of ozone gas at a constant concentration for 5, 10, and 15 min. The sample was then taken in a plastic container and stored at 35°C ± 2 for three months. The results revealed that ozone processing had a significant (p˂0.05) effect on the total phenolics (TP) contents, total flavonoids (TF) contents, total soluble solids (TSS), acidity, total antioxidant activity (TAA) and DDPH radical scavenging activity of Kinnow juice. In addition, the ozonation application also significantly (p˂0.05) decreased the population of the microbes when the ozone time was increased from 5-15 min. Among the treatments, it was observed that T
3
had the highest TSS, acidity, TF contents, TAA, and DDPH radical scavenging activity values and the lowest mold and plate counts. Regarding sensory qualities, T
0+
showed the highest sensory score during storage. Thus, it may be concluded from the findings of our study that ozone application improved the quality of Kinnow juice by increasing TSS, phytochemicals and decreasing the microbial population, thereby prolonging their shelf life.
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DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Wireless Sensor Network (WSN) is leading to a new paradigm of Internet of Everything (IoE). WSNs have a wide range of applications but are usually deployed in a particular application. However, the ...future of WSNs lies in the aggregation and allocation of resources, serving diverse applications. WSN virtualization by the middleware is an emerging concept that enables aggregation of multiple independent heterogeneous devices, networks, radios and software platforms; and enhancing application development. WSN virtualization, middleware can further be categorized into sensor virtualization and network virtualization. Middleware for WSN virtualization poses several challenges like efficient decoupling of networks, devices and software. In this paper efforts have been put forward to bring an overview of the previous and current middleware designs for WSN virtualization, the design goals, software architectures, abstracted services, testbeds and programming techniques. Furthermore, the paper also presents the proposed model, challenges and future opportunities for further research in the middleware designs for WSN virtualization.
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