Purpose
To determine the predictability of success and the risk of open conjunctival revision in the subsequent eye after XEN45 Gel Stent implantation according to lens status.
Methods
This was a ...retrospective single-centre study involving 132 eyes of 66 participants who had undergone intraocular pressure (IOP)-lowering XEN45 Gel Stent implantation, either as a standalone procedure in phakic and pseudophakic eyes or in combination with phacoemulsification. Successful surgery was defined by three scores: IOP at follow-up < 21 mmHg (score A) or < 18 mmHg (score B) and an IOP reduction > 20% or IOP ≤ 15 mmHg and an IOP reduction ≥ 40% (score C). In all scores, one open conjunctival revision was allowed, and additional repeat surgery was considered a failure. The predictability of success and revision rate depending on the outcome of the first eye were calculated using Bayes’ theorem.
Results
IOP-lowering did not differ significantly between the first and second eyes. Success rates of standalone surgery in the second eye after successful surgery in the first eye significantly exceed rates after prior failure. For the combined procedure, the rates did not differ significantly. For score A, we determined a 76.6% chance of success following a prior success and a 57.9% chance, if prior surgery failed. The corresponding probabilities were 75% and 59.1% for score B, while 66.7% and 15.7% for score C, respectively. We calculated a 60% risk for revision surgery in the standalone phakic group. If the first eye was not revised, the risk of revision in the subsequent eye was 20%. The corresponding risks were 72.7% and 5% for the standalone procedure in pseudophakic patients and 38.4% and 41.7% for the combined procedure, respectively.
Conclusion
The results of our study offer a tool to predict the outcome of subsequent eye surgeries based on either the outcome in the initial eye and the type of surgery performed, owing to the high predictive potential.
Aims. We performed a spatially resolved spectral X-ray study of the pulsar wind nebula (PWN) in the supernova remnant G0.9+0.1. Furthermore, we modeled its nonthermal emission in the X-ray and very ...high-energy (VHE, E > 100 GeV) γ-ray regime. Methods. Using Chandra ACIS-S3 data, we investigated the east-west dependence of the spectral properties of G0.9+0.1 by calculating hardness ratios. We analyzed the EPIC-MOS and EPIC-pn data of two on-axis observations of the XMM-Newton telescope and extracted spectra of four annulus-shaped regions, centered on the region of brightest emission of the source. A radially symmetric leptonic model was applied in order to reproduce the observed X-ray emission of the inner part of the PWN. Using the optimized model parameter values obtained from the X-ray analysis, we then compared the modeled inverse Compton (IC) radiation with the published H.E.S.S. γ-ray data. Results. The spectral index within the four annuli increases with growing distance to the pulsar, whereas the surface brightness drops. With the adopted model we are able to reproduce the characteristics of the X-ray spectra. The model results for the VHE γ radiation, however, strongly deviate from the H.E.S.S. data.
Purpose
To determine the impact of failed ab-interno trabeculectomy on the postoperative outcome of subsequent XEN45 gel stent (Allergan, CA, USA) implantation in pseudophakic eyes.
Methods
In this ...retrospective single-center study, we included 60 pseudophakic eyes from 60 participants who underwent XEN45 gel stent implantation. Thirty eyes each underwent primary stent implantation (control group) or had previously undergone a failed ab-interno trabeculectomy (trabectome group). The groups were matched at a 1:1 ratio based on the following criteria: preoperative and maximum Intraocular pressure (IOP), preoperative medication score, cup/disk-ratio, follow-up time, best-corrected visual acuity at baseline, age, and the proportion of patients classified as primary open angle glaucoma or exfoliation glaucoma. We defined a successful surgery by the following three scores: an IOP reduction > 20% and IOP at the longest follow-up < 21 mmHg (Score A) or < 18 mmHg (Score B) or IOP ≤ 15 mmHg and an IOP reduction ≥ 40% (Score C). One open conjunctival revision was allowed in all scores, and a repeat surgery was considered a failure.
Results
Following an average follow-up period of 22 ± 12 months, we observed a mean IOP reduction of 38%, from 23.5 ± 5.2–14.5 ± 5.0 mmHg. Comparative analyses between the groups did not reveal a significant difference in the postoperative IOP, postoperative medication score, side effects, revision rate, repeat surgery rate, or success rate.
Conclusions
Trabectome is a viable first-line procedure for medically uncontrolled glaucoma before filtering ab-interno microstent surgery is considered.
Two series of LaMnO3 supported noble metal (Pt, Pd, Rh) catalysts prepared by the citrate method and calcined in air at 600 and 800 °C, respectively, were investigated. The catalysts resulting from ...method A were prepared by simultaneous incorporation of the noble metals during perovskite preparation and those following method B were generated by impregnation of the calcined perovskites with the noble metal compounds. The noble metals form solid solutions with the perovskite lattice. Reduction of the catalysts with hydrogen prior to the catalytic reaction led to a significant enhancement of the catalytic activity. During the catalytic reaction, the noble metal clusters are partially transformed to highly dispersed noble metal oxides or nonstoichiometric noble metal oxide phases, which are the catalytically active phases for the total oxidation of methane. The best results were obtained with the Pd containing catalysts prepared by method B.
Two series of LaMnO3 supported noble metal (Pt, Pd, Rh) catalysts prepared by different methods are investigated for the total oxidation of methane. Reduction of the catalysts with hydrogen prior to the catalytic reaction leads to a significant enhancement of the catalytic activity and noble metal clusters are partially transformed to active sites during catalytic action.
Abstract
We report the discovery of four Fast Radio Bursts (FRBs) in the ongoing SUrvey for Pulsars and Extragalactic Radio Bursts at the Parkes Radio Telescope: FRBs 150610, 151206, 151230 and ...160102. Our real-time discoveries have enabled us to conduct extensive, rapid multimessenger follow-up at 12 major facilities sensitive to radio, optical, X-ray, gamma-ray photons and neutrinos on time-scales ranging from an hour to a few months post-burst. No counterparts to the FRBs were found and we provide upper limits on afterglow luminosities. None of the FRBs were seen to repeat. Formal fits to all FRBs show hints of scattering while their intrinsic widths are unresolved in time. FRB 151206 is at low Galactic latitude, FRB 151230 shows a sharp spectral cut-off, and FRB 160102 has the highest dispersion measure (DM = 2596.1 ± 0.3 pc cm−3) detected to date. Three of the FRBs have high dispersion measures (DM > 1500 pc cm−3), favouring a scenario where the DM is dominated by contributions from the intergalactic medium. The slope of the Parkes FRB source counts distribution with fluences >2 Jy ms is $\alpha =-2.2^{+0.6}_{-1.2}$ and still consistent with a Euclidean distribution (α = −3/2). We also find that the all-sky rate is $1.7^{+1.5}_{-0.9}\times 10^3$FRBs/(4π sr)/day above ${\sim }2{\rm \, }\rm {Jy}{\rm \, }\rm {ms}$ and there is currently no strong evidence for a latitude-dependent FRB sky rate.
Letter of intent for KM3NeT 2.0 Adrián-Martínez, S; Aharonian, F; Aiello, S ...
Journal of physics. G, Nuclear and particle physics,
08/2016, Letnik:
43, Številka:
8
Journal Article, Publication
Recenzirano
Odprti dostop
The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of ...neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the high-energy astrophysical neutrino signal reported by IceCube and (2) the sizable contribution of electron neutrinos to the third neutrino mass eigenstate as reported by Daya Bay, Reno and others. To meet these objectives, the KM3NeT Collaboration plans to build a new Research Infrastructure consisting of a network of deep-sea neutrino telescopes in the Mediterranean Sea. A phased and distributed implementation is pursued which maximises the access to regional funds, the availability of human resources and the synergistic opportunities for the Earth and sea sciences community. Three suitable deep-sea sites are selected, namely off-shore Toulon (France), Capo Passero (Sicily, Italy) and Pylos (Peloponnese, Greece). The infrastructure will consist of three so-called building blocks. A building block comprises 115 strings, each string comprises 18 optical modules and each optical module comprises 31 photo-multiplier tubes. Each building block thus constitutes a three-dimensional array of photo sensors that can be used to detect the Cherenkov light produced by relativistic particles emerging from neutrino interactions. Two building blocks will be sparsely configured to fully explore the IceCube signal with similar instrumented volume, different methodology, improved resolution and complementary field of view, including the galactic plane. One building block will be densely configured to precisely measure atmospheric neutrino oscillations.
A search for cosmic neutrino sources using the data collected with the ANTARES neutrino telescope between early 2007 and the end of 2015 is performed. For the first time, all neutrino ...interactions-charged- and neutral-current interactions of all flavors-are considered in a search for point-like sources with the ANTARES detector. In previous analyses, only muon neutrino charged-current interactions were used. This is achieved by using a novel reconstruction algorithm for shower-like events in addition to the standard muon track reconstruction. The shower channel contributes about 23% of all signal events for an E−2 energy spectrum. No significant excess over background is found. The most signal-like cluster of events is located at (α,δ)=(343.8°,23.5°) with a significance of 1.9σ. The neutrino flux sensitivity of the search is about E2dΦ/dE=6×10−9 GeV cm−2 s−1 for declinations from −90° up to −42°, and below 10−8 GeV cm−2 s−1 for declinations up to 5°. The directions of 106 source candidates and 13 muon track events from the IceCube high-energy sample events are investigated for a possible neutrino signal and upper limits on the signal flux are determined.
Abstract
Gamma-ray bursts are thought to be sites of hadronic acceleration, thus neutrinos are expected from the decay of charged particles, produced in pγ interactions. The methods and results of a ...search for muon neutrinos in the data of the ANTARES neutrino telescope from four bright GRBs (GRB 080916C, GRB 110918A, GRB 130427A and GRB 130505A) observed between 2008 and 2013 are presented. Two scenarios of the fireball model have been investigated: the internal shock scenario, leading to the production of neutrinos with energies mainly above 100 TeV, and the photospheric scenario, characterized by a low-energy component in neutrino spectra due to the assumption of neutrino production closer to the central engine. Since no neutrino events have been detected in temporal and spatial coincidence with these bursts, upper limits at 90 per cent confidence level on the expected neutrino fluxes are derived. The non-detection allows for directly constraining the bulk Lorentz factor of the jet Γ and the baryon loading fp.
The catalytic behavior of ZrO2 and ZrO2 containing 8 mol‐% Y2O3 supported A1–xSrxMnO3 (A = La, didymium) perovskites was studied in the total oxidation of methane, chloromethane and dichloromethane ...considering catalyst deactivation and byproduct formation. The perovskites are dispersed on the support surface; clusters with a perovskite‐like structure were formed. The supported catalysts are characterized by higher specific surface areas compared with the unsupported ones. Partial substitution of A‐site cations by Sr leads to an enhancement of the catalytic activity in the total oxidation of methane, but not in the total oxidation of chlorinated hydrocarbons (CHC). The catalytic activity of supported and unsupported catalysts is comparable in the total oxidation of methane in spite of the significantly lower perovskite content of the supported catalysts. In the CHC conversion the catalytic activity of the supported catalysts is higher than that of the unsupported ones.
The catalytic activity and selectivity of A1–xSrxMnO3 perovskites supported on ZrO2 and ZrO2 containing 8 mol‐% Y2O3 for the total oxidation of methane, chloromethane and dichloromethane was investigated. Furthermore, the catalytic behavior of perovskites containing lanthanum and/or didymium was compared. Didymium oxide as a cheap rare earth metal oxide mixture is of interest from the technical point of view for the preparation of perovskite‐type oxide catalysts.
PDF
