We report spectroscopic observation of Rydberg polarons in an atomic Bose gas. Polarons are created by excitation of Rydberg atoms as impurities in a strontium Bose-Einstein condensate. They are ...distinguished from previously studied polarons by macroscopic occupation of bound molecular states that arise from scattering of the weakly bound Rydberg electron from ground-state atoms. The absence of a p-wave resonance in the low-energy electron-atom scattering in Sr introduces a universal behavior in the Rydberg spectral line shape and in scaling of the spectral width (narrowing) with the Rydberg principal quantum number, n. Spectral features are described with a functional determinant approach (FDA) that solves an extended Fröhlich Hamiltonian for a mobile impurity in a Bose gas. Excited states of polyatomic Rydberg molecules (trimers, tetrameters, and pentamers) are experimentally resolved and accurately reproduced with a FDA.
A discrete degree of freedom can be engineered to match the Hamiltonian of particles moving in a real-space lattice potential. Such synthetic dimensions are powerful tools for quantum simulation ...because of the control they offer and the ability to create configurations difficult to access in real space. Here, in an ultracold
Sr atom, we demonstrate a synthetic-dimension based on Rydberg levels coupled with millimeter waves. Tunneling amplitudes between synthetic lattice sites and on-site potentials are set by the millimeter-wave amplitudes and detunings respectively. Alternating weak and strong tunneling in a one-dimensional configuration realizes the single-particle Su-Schrieffer-Heeger (SSH) Hamiltonian, a paradigmatic model of topological matter. Band structure is probed through optical excitation from the ground state to Rydberg levels, revealing symmetry-protected topological edge states at zero energy. Edge-state energies are robust to perturbations of tunneling-rates that preserve chiral symmetry, but can be shifted by the introduction of on-site potentials.
We demonstrate magnetic confinement of an ultracold neutral plasma (UCNP) created at the null of a biconic cusp, or quadrupole magnetic field. Initially, the UCNP expands due to electron thermal ...pressure. As the plasma encounters stronger fields, expansion slows and the density distribution molds to the field. UCNP electrons are strongly magnetized over most of the plasma, while ion magnetization is only significant at the boundaries. Observations suggest that electrons and ions are predominantly trapped by magnetic mirroring and ambipolar electric fields, respectively. Confinement times approach 0.5 ms, while unmagnetized plasmas dissipate on a timescale of a few tens of microseconds.
Recently, biomedical research has moved toward cell culture in three dimensions to better recapitulate native cellular environments. This protocol describes one method for 3D culture, the magnetic ...levitation method (MLM), in which cells bind with a magnetic nanoparticle assembly overnight to render them magnetic. When resuspended in medium, an external magnetic field levitates and concentrates cells at the air-liquid interface, where they aggregate to form larger 3D cultures. The resulting cultures are dense, can synthesize extracellular matrix (ECM) and can be analyzed similarly to the other culture systems using techniques such as immunohistochemical analysis (IHC), western blotting and other biochemical assays. This protocol details the MLM and other associated techniques (cell culture, imaging and IHC) adapted for the MLM. The MLM requires 45 min of working time over 2 d to create 3D cultures that can be cultured in the long term (>7 d).
Cell culture is an essential tool in drug discovery, tissue engineering and stem cell research. Conventional tissue culture produces two-dimensional cell growth with gene expression, signalling and ...morphology that can be different from those found in vivo, and this compromises its clinical relevance. Here, we report a three-dimensional tissue culture based on magnetic levitation of cells in the presence of a hydrogel consisting of gold, magnetic iron oxide nanoparticles and filamentous bacteriophage. By spatially controlling the magnetic field, the geometry of the cell mass can be manipulated, and multicellular clustering of different cell types in co-culture can be achieved. Magnetically levitated human glioblastoma cells showed similar protein expression profiles to those observed in human tumour xenografts. Taken together, these results indicate that levitated three-dimensional culture with magnetized phage-based hydrogels more closely recapitulates in vivo protein expression and may be more feasible for long-term multicellular studies.
Ultracold neutral plasmas formed by photoionizing laser-cooled atoms near the ionization threshold have electron temperatures in the 1–1000
K range and ion temperatures from tens of millikelvin to a ...few Kelvin. They represent a new frontier in the study of neutral plasmas, which traditionally deals with much hotter systems, but they also blur the boundaries of plasma, atomic, condensed matter, and low temperature physics. Modeling these plasmas challenges computational techniques and theories of non-equilibrium systems, so the field has attracted great interest from the theoretical and computational physics communities. By varying laser intensities and wavelengths it is possible to accurately set the initial plasma density and energy, and charged-particle-detection and optical diagnostics allow precise measurements for comparison with theoretical predictions.
Recent experiments using optical probes demonstrated that ions in the plasma equilibrate in a strongly coupled fluid phase. Strongly coupled plasmas, in which the electrical interaction energy between charged particles exceeds the average kinetic energy, reverse the traditional energy hierarchy underlying basic plasma concepts such as Debye screening and hydrodynamics. Equilibration in this regime is of particular interest because it involves the establishment of spatial correlations between particles, and it connects to the physics of the interiors of gas-giant planets and inertial confinement fusion devices.
We propose and analyze a new scheme to produce ultracold neutral plasmas deep in the strongly coupled regime. The method exploits the interaction blockade between cold atoms excited to high-lying ...Rydberg states and therefore does not require substantial extensions of current ultracold plasma experiments. Extensive simulations reveal a universal behavior of the resulting Coulomb coupling parameter, providing a direct connection between the physics of strongly correlated Rydberg gases and ultracold plasmas. The approach is shown to reduce currently accessible temperatures by more than an order of magnitude, which opens up a new regime for ultracold plasma research and cold ion-beam applications with readily available experimental techniques.
We demonstrate control of the collapse and expansion of an (88)Sr Bose-Einstein condensate using an optical Feshbach resonance near the (1)S(0)-(3)P(1) intercombination transition at 689 nm. ...Significant changes in dynamics are caused by modifications of scattering length by up to ± 10a(bg), where the background scattering length of (88)Sr is a(bg) = -2a(0) (1a(0) = 0.053 nm). Changes in scattering length are monitored through changes in the size of the condensate after a time-of-flight measurement. Because the background scattering length is close to zero, blue detuning of the optical Feshbach resonance laser with respect to a photoassociative resonance leads to increased interaction energy and a faster condensate expansion, whereas red detuning triggers a collapse of the condensate. The results are modeled with the time-dependent nonlinear Gross-Pitaevskii equation.
We present a study of the collisional relaxation of ion velocities in a strongly coupled, ultracold neutral plasma on short time scales compared to the inverse collision rate. The measured average ...velocity of a tagged population of ions is shown to be equivalent to the ion-velocity autocorrelation function. We thus gain access to fundamental aspects of the single-particle dynamics in strongly coupled plasmas and to the ion self-diffusion constant under conditions where experimental measurements have been lacking. Nonexponential decay towards equilibrium of the average velocity heralds non-Markovian dynamics that are not predicted by traditional descriptions of weakly coupled plasmas. This demonstrates the utility of ultracold neutral plasmas for studying the effects of strong coupling on collisional processes, which is of interest for dense laboratory and astrophysical plasmas.
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