치유의 숲에 적합한 간벌형식과 방법 김웅진(Woong Jin Kim); 연평식(Pyung Sik Yeoun); 김윤희(Youn Hee Kim) ...
인간식물환경학회지,
10/2015, Letnik:
18, Številka:
5
Journal Article
Recenzirano
This study was conducted to suggest a thinning method to find out materials needed and preserve forest for forest healing programs. A Delphi survey was implemented to draw survey questions necessary ...for taking care of healing forest; a survey for people who have career in forest healing program was also conducted to figure out the importance of storytelling trees. The result showed that the suitable thinning method for healing forest is the eclectic method of quantitative and qualitative thinning methods. There were 10 tree types in the importance of selecting storytelling trees: dead wood in ecological state, unusual type of wood, fragrant wood, another trees standing independently in the main tree group, flowering trees, trees bearing fruit to taste, wood with a distinctive bark, wider and larger trees, wood for medical use and tree extending to various degrees at chest height in the following order. Therefore, considering 10 tree types above it is recommended to preserve and take care of trees for storytelling in healing forest.
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•We prepare a perylenetetracarboxylicdiimide probe connected with admantane unit.•The probe exhibits a colorimetric transition with Fe3+ and Al3+ ions.•The probe responds sensitively ...at micromolar concentrations.•We determine the stoichiometry and binding constant by analytical methods.
We report the synthesis of a new colorimetric probe R1, in which the perylene tetracarboxylicdiimide fluorophore is connected with an adamantly amine unit through the NH binding site. R1 was tested with a variety of metal ions and exhibited a significant colorimetric transition in the presence of Fe3+ and Al3+ ions. No significant changes were observed with other metal ions. Absorption measurements indicated that trivalent metal ions Fe3+/Al3+ bind with R1 and generate a stable complex. The presence of Fe3+ and Al3+ ions induces new absorption bands with shoulder peaks at 525nm and 568nm. The fluorescence intensity of R1 at 579nm was significantly increased by the addition of Fe3+or Al3+ ions. Furthermore, R1 was found to be sensitive towards these metal ions at micromolar concentrations. The stoichiometry of R1:Fe3+/Al3+ complexes were confirmed by ESI–MS analysis, and binding constants were calculated using Benesi–Hildebrand plots. The binding mode of R1 with metal ions was proposed based on optimized structure from DFT calculation.
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We propose a polymeric nanovehicles (PNVs)-based enhanced transdermal delivery platform. A technical advance can be found in that delivery efficiency is significantly enhanced by ...effective adhesion of PNVs to the cell membrane, which is characterized noninvasively by using a confocal laser scanning microscopy (CLSM)-based skin visualization technique. To this end, the PNVs with a soft core phase were fabricated through co-assembly of two amphiphilic triblock copolymers, poly(ethylene oxide)-b-poly(ε-caprolactone)-b-poly(ethylene oxide) (PEO-b-PCL-b-PEO) and poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (PEO-b-PPO-b-PEO). The softness of PNVs was tuned successfully, while maintaining the particle size at ∼110 nm, by incorporation of PEO-b-PPO-b-PEO into the PNVs to a volume fraction of 0.3. Through an ex vivo skin penetration test, we showed that transactivating transcriptional activator (TAT)-decorated soft PNVs could not only exert strong adhesion to skin but also increase cellular uptake, leading to a transdermal delivery efficiency that is twice that of a hard PNV control. Moreover, CLSM-based noninvasive visualization of a fluorescent drug probe in the skin showed that the adhesiveness and softness of the PNVs contributed directly to the enhancement of transdermal delivery.
Purpose To compare the accuracy of ultrasonography (US), single-energy CT (SECT), dual-energy CT (DECT), MR imaging (MRI), and MR spectroscopy (MRS) for detecting fatty liver in a rat model. ...Materials and Methods Fatty liver was induced by 60% high-fat diet for 1, 2, 3, 4, or 5 weeks (3 rats per group, a total of 15 rats). The control group comprised of five rats fed 10% high-fat diet. US, SECT, DECT, MRI, and MRS of the liver were performed weekly. Histologic steatosis grade and intrahepatocelluar triglyceride level were determined histologically for the livers of sacrificed rats. Pearson correlation test was used to assess the correlation between examinations and standard reference levels. Receiver operating characteristic curves were constructed. Area under the curve (AUC), sensitivity, and specificity were calculated. Results US, SECT, DECT, MRI, and MRS were significantly correlated with histologic steatosis grade. The diagnostic performance of AUC, sensitivity, and specificity were 0.893, 80%, and 80% for US, 0.960, 80%, and 80% for SECT, 0.947, 100%, and 60% for DECT, 0.933, 93.3%, and 100% for MRI, and 0.960, 93.3%, and 100% for MRS. Conclusion MRS showed the strongest correlation with histologic steatosis grade with the highest sensitivity and specificity for diagnosis of fatty liver compared to other modalities.
Homogenously zinc oxide (ZnO)-dispersed polymethylmethacrylate (PMMA) composite microspheres were produced considering the interfacial characteristics of ZnO and PMMA in in situ suspension ...polymerization. The morphological observation with electron microscopes revealed that nano-sized ZnO particles were embedded homogeneously in the inner part of PMMA microspheres. Moreover, their spherical shape could be maintained to a large amount of ZnO in the PMMA phase. From this study, it was found that one of key requirements in the synthesis of inorganic/polymer composite microspheres was the enhanced interfacial compatibility between inorganic and polymer, which was achieved by treating the surface of inorganics hydrophobically and imparting conformational anchorage factor at inorganic interfaces.
A neurofibroma is a benign tumor of the peripheral nerve sheath characterized by proliferation of Schwann cells, perineural cells, and endoneurial fibroblasts. Different types of neurofibromas can be ...identified, including localized, plexiform, and diffuse types. Neurofibromas can involve any site on the body skin. The diffuse variant is rare and occurs primarily in children and young adults. It involves the skin and subcutaneous tissue in a plaque-like fashion on the head and neck regions. We present a case of a 10-year-old boy who had a diffuse neurofibroma on the scalp.
The aim of the current study was to assess the influences of valproate (VPA) on the language functions in newly diagnosed pediatric patients with epilepsy. We reviewed medical records of 53 newly ...diagnosed patients with epilepsy, who were being treated with VPA monotherapy (n=53; 22 male patients and 31 female patients). The subjects underwent standardized language tests, at least twice, before and after the initiation of VPA. The standardized language tests used were The Test of Language Problem Solving Abilities, a Korean version of The Expressive/Receptive Language Function Test, and the Urimal Test of Articulation and Phonology. Since all the patients analyzed spoke Korean as their first language, we used Korean language tests to reduce the bias within the data. All the language parameters of the Test of Language Problem Solving Abilities slightly improved after the initiation of VPA in the 53 pediatric patients with epilepsy (mean age: 11.6±3.2years), but only “prediction” was statistically significant (determining cause, 14.9±5.1 to 15.5±4.3; making inference, 16.1±5.8 to 16.9±5.6; prediction, 11.1±4.9 to 11.9±4.2; total score of TOPS, 42.0±14.4 to 44.2±12.5). The patients treated with VPA also exhibited a small extension in mean length of utterance in words (MLU-w) when responding, but this was not statistically significant (determining cause, 5.4±2.0 to 5.7±1.6; making inference, 5.8±2.2 to 6.0±1.8; prediction, 5.9±2.5 to 5.9±2.1; total, 5.7±2.1 to 5.9±1.7). The administration of VPA led to a slight, but not statistically significant, improvement in the receptive language function (range: 144.7±41.1 to 148.2±39.7). Finally, there were no statistically significant changes in the percentage of articulation performance after taking VPA. Therefore, our data suggested that VPA did not have negative impact on the language function, but rather slightly improved problem-solving abilities.
•Antiepileptic drugs may cause language impairment.•Children who take antiepileptic drugs should be monitored for language function.•Valproate did not have any significant deteriorative effects on language function.•Valproate is a safe antiepileptic drug with regard to language function.
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