Samples of the bimetallic-based NH2-MIL-125(Ti) at a ratio of Mn+/Ti4+ is 0.15 (Mn+: Ni2+, Co2+ and Fe3+) were first synthesized using the solvothermal method. Their fundamental properties were ...analyzed by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Raman spectra, scanning electron microscopy (SEM), N2 adsorption–desorption measurements, and UV–Vis diffuse reflectance spectroscopy (UV-Vis DRS). The as-acquired materials were used as high-efficiency heterogeneous photocatalysts to remove Rhodamine B (RhB) dye under visible light. The results verified that 82.4% of the RhB (3 × 10−5 M) was degraded within 120 min by 15% Fe/Ti−MOFs. Furthermore, in the purpose of degrading Rhodamine B (RhB), the rate constant for the 15% Fe/Ti-MOFs was found to be 2.6 times as fast as that of NH2-MIL-125(Ti). Moreover, the 15% Fe/Ti-MOFs photocatalysts remained stable after three consecutive cycles. The trapping test demonstrated that the major active species in the degradation of the RhB process were hydroxyl radicals (HO∙) and holes (h+).
Display omitted
•A new polycation PVBTAC-modified ZnO/SiO2 nanocomposite based on rice husk was successfully fabricated.•The optimum conditions for DCF removal using PVBTAC-modified ZnO/SiO2 were ...contact time 90 min, pH 8 and dosage 10 mg/mL.•The maximum adsorption capacity of DCF was 66 mg/g and the removal efficiency was 91.8%.•After four regenerations, the DCF removal using PVBTAC modified ZnO/SiO2 was still greater than 84%.•The E.coli removal was greater than 88 % that was controlled by electrostatic and non-electrostatic interactions.
The present study investigated the adsorptive removal of non-steroidal medication diclofenac (DCF) using polycation, PVBTAC modified zinc oxide/silica nanocomposite (ZnO/SiO2). The ZnO/SiO2 which was fabricated based on nanosilica rice, was examined by XRD, FT-IR, TEM, EDX, and zeta potential measurements. Surface of ZnO/SiO2 was modified by PVBTAC adsorption at pH 9 and 100 mM KCl to reverse the high charge of material. The optimum parameters for DCF removal using PVBTAC-modified ZnO/SiO2 were contact time 90 min, pH 8 and adsorbent dosage 10 mg/mL. The maximum adsorption capacity and the removal efficiency of DCF were found to be 66 mg/g and 91.8%, respectively, while the bacteria Escherichiacoli(E.coli) removal reached greater than 88 %. Adsorption of DCF on PVBTAC-modified ZnO/SiO2 was mainly controlled by electrostatic attraction between anionic DCF molecules and positively charged PVBTAC-modified ZnO/SiO2 surface whereas the E.coli removal was controlled by both electrostatic and non-electrostatic interactions. Adsorption isotherms of DCF on PVBTAC-modified ZnO/SiO2 at different ionic strengths were reasonably represented by a two-step model while adsorption kinetics fitted well with the pseudo-second-order model. After four regenerations of PVBTAC modified ZnO/SiO2, the DCF removal still exceeded 84%. Our materialis agreat performance adsorbent to remove pharmaceutical and bacteria.
Mpox was diagnosed in 2 women returning to Vietnam from the United Arab Emirates. The monkeypox viruses belonged to an emerging sublineage, A.2.1, distinct from B.1, which is responsible for the ...ongoing multicountry outbreak. Women could contribute to mpox transmission, and enhanced genomic surveillance is needed to clarify pathogen evolution.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, ODKLJ, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Spherical-shaped brookite TiO
2
nanoparticles, average size of about ∼ 10 nm, have been prepared by a hydrothermal method at 175°C for 7 h using HCl acid medium at a concentration of 3.0 M and ...amorphous TiO
2
as precursor that was synthesized by the sol–gel method. Under the sunlight equivalent ultraviolet A (UV-A) irradiation, this brookite acts as an efficient photocatalyst for the photodegradation of recalcitrant pharmaceuticals (e.g., cinnamic acid, ibuprofen, and diatrizoic acid). The photocatalytic assay was conducted using a high pharmaceutical load and a low photocatalyst amount, corresponding to a fixed photocatalyst/pharmaceutical mass ratio of 4. The photodegradation of the pharmaceuticals was followed by a combination of ultraviolet/visible (UV/Vis) absorption spectroscopic, total organic carbon (TOC), and electrospray ionisation time-of-flight mass (ESI–TOF–MS) measurements. Scavenger experiments were carried out to confirm the importance of active species including holes and superoxide radicals acting as “door openers” in the photodegradation of pharmaceuticals in terms of aromatic ring opening, thus facilitating complete mineralization.
Brookite TiO2 nanoparticles were synthesized by hydrothermal method and characterized by X-ray powder diffraction (XRD), diffuse reflectance UV–Visible spectroscopy (DRUV), and scanning electron ...microscopy (SEM). The obtained particles were spherical in shape with the diameter of about ~10 nm under the hydrothermal temperature of 175 °C. The photocatalytic performance of brookite was investigated in the photodegradation of dyes (rhodamine B and rose bengal) under UV-A radiation by low-power lamp. The activity of brookite and the photodegradation efficiency of dyes were estimated using a UV–Visible spectrophotometer and a total organic carbon (TOC) analyzer. Compared to anatase and rutile prepared by the similar synthesis procedure, brookite is highly active in terms of decolourization, aromatic ring opening, and mineralization.
Display omitted
•Highly crystalline brookite nanoparticles were synthesized by hydrothermal method.•Brookite is highly active under low power UV–vis irradiation and high dye loading.•Decolourization of dyes is compared to abatement of aromatic ring and mineralization.
Display omitted
•A rapid, scalable synthesis of carbon quantum dots is demonstrated.•Carbon quantum dots are formed in glycerol by simply heating.•The absorption and emission properties are dominated ...by surface fluorophores.•Ten-gram scale is possible per bath synthesis.
Scaling up the synthesis carbon quantum dots (CQDs) is highly demanded for the deployment of CQDs in diverse applications. Herein, we used glycerol (Gly) as high boiling point solvent that enables scalable synthesis of CQDs from mixtures of citric acid (CA) and ethylenediamine (EDA) within few minutes by either thermal heating or microwave. Purified CQDs were spherical with a diameter varying from 2 to 8 nm. The CQDs exhibited a resolved UV absorption band at about 346 nm and a broad photoluminescence (PL) spectrum with a PL quantum yield of 49.9%.
Despite their promise, circulating tumor DNA (ctDNA)-based assays for multi-cancer early detection face challenges in test performance, due mostly to the limited abundance of ctDNA and its inherent ...variability. To address these challenges, published assays to date demanded a very high-depth sequencing, resulting in an elevated price of test. Herein, we developed a multimodal assay called SPOT-MAS (screening for the presence of tumor by methylation and size) to simultaneously profile methylomics, fragmentomics, copy number, and end motifs in a single workflow using targeted and shallow genome-wide sequencing (~0.55×) of cell-free DNA. We applied SPOT-MAS to 738 non-metastatic patients with breast, colorectal, gastric, lung, and liver cancer, and 1550 healthy controls. We then employed machine learning to extract multiple cancer and tissue-specific signatures for detecting and locating cancer. SPOT-MAS successfully detected the five cancer types with a sensitivity of 72.4% at 97.0% specificity. The sensitivities for detecting early-stage cancers were 73.9% and 62.3% for stages I and II, respectively, increasing to 88.3% for non-metastatic stage IIIA. For tumor-of-origin, our assay achieved an accuracy of 0.7. Our study demonstrates comparable performance to other ctDNA-based assays while requiring significantly lower sequencing depth, making it economically feasible for population-wide screening.
Vietnam has a high thalassemia burden. We collected blood samples from 5880 pregnant Vietnamese women during prenatal health checks to assess thalassemia carrier frequency using combined ...gap-polymerase chain reaction (gap-PCR) and targeted next-generation sequencing (NGS). Thalassemia carriers were identified with prevalence of 13.13% (772), including 7.82% (460) carriers of α-thalassemia (α-thal), 5.31% (312) carriers of β-thalassemia (β-thal), and 0.63% (37) concurrent α-/β-thal carriers. Deletional mutations (368) accounted for 80.0% of α-thal carriers, of which, --
SEA
(Southeast Asian) (n = 254; 55.0%) was most prevalent, followed by the -α
3.7
(rightward) (n = 66; 14.0%) and -α
4.2
(leftward) (n = 45; 9.8%) deletions. Hb Westmead (HBA2: c.369C>G) (n = 53) and Hb Constant Spring (Hb CS or HBA2: c.427T>C) (in 28) are the two most common nondeletional α-globin variants, accounting for 11.5 and 6.0% of α-thal carriers. We detected 11 different β-thal genotypes. Hb E (HBB: c.79G>A) (in 211) accounted for 67.6% of β-thal carriers. The most common β-thal genotypes were associated with mutations at codon 17 (A>T) (HBB: c.52A>T), codons 41/42 (-TTCT) (HBB: c.126_129delCTTT), and codon 71/72 (+A) (HBB: c.217_218insA) (prevalence 0.70%, 0.68%, and 0.2%, respectively). Based on mutation frequencies calculated in this study, estimates of 5021 babies in Vietnam are affected with clinically severe thalassemia annually. Our data suggest a higher thalassemia carrier frequency in Vietnam than previously reported. We established that combining NGS with gap-PCR creates an effective large-scale thalassemia screening method that can detect a broad range of mutations.
Celotno besedilo
Dostopno za:
DOBA, IJS, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
In this work, an environmentally friendly and cost-effective synthetic method of silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) was successfully performed using aqueous extract of
...Phlogacanthus turgidus
(PT) leaves. The biosynthesis of nanoparticles was optimized for reaction conditions including concentration of metallic ions, temperature, and time using the measurement of UV–Vis spectroscopy. The nanoparticles were well characterized by analytic techniques such as Fourier-transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), high-resolution transmission electron microscope (HR-TEM), and selected area electron diffraction (SAED). The morphological data showed that PT-AgNPs possessed the spherical shape with the size distribution ranging from 5 to 15 nm with a mean size of 10 nm while PT-AuNPs existed in the multiple shape with the size distribution ranging from 5 to 20 nm with a mean size of 12 nm. The antibacterial behavior showed that PT-AgNPs possessed high bioactivity against four bacterial strains including
Bacillus subtilis
,
Staphylococcus aureus, Salmonella typhi
, and
Escherichia coli.
Moreover, the catalytic activity of the biogenic nanoparticles was investigated for catalytic reduction of 2-nitrophenol, 3-nitrophenol, and rhodamine B. The kinetic data showed that the nanoparticles were excellent catalysts with potential applications for environmental treatment.
Graphical abstract
PDF
