Achilles tendon and skin tuberous xanthomas are often found in patients with type II and III hyperlipidemia, especially in familial hypercholesterolemia. However, a 21-year-old female patient had a ...large tuberous xanthomas on both elbows and xanthomas of achilles tendon without hyperlipidemia and had normal functioning of LDL receptors. It is known that xanthomas with normolipidemia is observed in patients with cerebrotendinous xanthomatosis (CTX) which have following several complications such as neurologic dysfunction, dementia, cataracts, premature atherosclerosis, etc., and in patients with sitosterolemia. CTX shows dysfunction in bile acids synthesis and also elevation of serum cholesterol concentration. In general, the formation of xanthomas in CTX has been considered to associate with the accumulation of cholesterol. However, the patient had no clinical findings of CTX except xanthomas. And, the patient presented dysfunction in bile acid synthesis (accumulation of abnormal bile alcohol in serum and urine, and abnormality of bile acid and bile salt composition in bile). But did not have elevation of serum cholesterol concentration. The mechanisms forming xanthomas in this patient is not clear. If this patient is thought to be one of the atypical type of CTX, it might be suggested that cholesterol does not associate the formation of xanthomas, but influences neurological dysfunction.
X(3)of M-X Chains Iwasa, Y.; Funatsu, E.; Koda, T. ...
Molecular crystals and liquid crystals science and technology. Section A, Molecular crystals and liquid crystals,
19/6/1/, Letnik:
217, Številka:
1
Journal Article
The third-order nonlinear optical susceptibility has been investigated for oriented thin films of halogen bridged platinum complexes. The | χ
(3)
(−3ω;ω,ω,ω) | spectrum associated with the third ...harmonic generation (THG) was measured by the Maker fringe method in the region of fundamental wavelength 0.6 μm∼1μm and 1.6μm∼2.2μ m. In the | χ | spectra, we found a peak structure at ω ∼ 1.8eV that is attributable to a two-photon resonance to the optically forbidden charge transfer exciton. The | χ
(3)
| value was in the order of 10
−11
esu that is comparable to the π-conjugated polymers. Common features of NL0 processes for the one-dimensional semiconductors are discussed.
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