The effect of four enzyme preparations (EP), Bacillolysin, Agroprot, Protozyme, and Protozyme C (Russia), on the protein and peptide profiles of the protein isolate isolated from peas of the Focor ...variety, as well as on its smell and taste, was investigated in this work. It was shown that enzyme treatment can improve the odor characteristics of the isolate. Thus, it was possible to reduce significantly the severity of the bean and herbal smell. At the same time, enzyme treatment also improved the taste of the isolate: it was possible to reduce significantly the severity of disturbing flavors such as leguminous, astringent, bitter, and herbal. The results obtained allowed us to select EP (fungal acid aspartic protease) to improve the organoleptic parameters of pea protein isolates intended for the production of meat and dairy product analogs.
Aim. To characterize clinical and epidemiological features of adult Berkitt's lymphoma (BL). Material and methods. The trial enrolled 72 patients (51 males and 21 females, age 14-69, mean age 27 ...years) treated in 1995-2008. Results. Stage I BL (by S.B. Murphy) was diagnosed in 5 patients, stage II - in 9, stage III - in 25, IV - in 14 patients, B-cell acute lymphoblastic leukemia (ALL) (L3) - in 19 patients. Intoxication was seen in 56(78%) patients, 38% patients had severe cachexia. Elevated concentration of lactatedehydrogenase (LDG) was detected in 57(79%) patients. In all the cases clinical symptoms developed for 1-3 months, median 6 weeks. Bone marrow involvement was diagnosed in 22 (31%) patients, CNS was affected in 17(24%) patients, of them 14 were males. Fifty two (72%) patients had abdominal, retroperitoneal and/or small pelvis tumors. Intestinal, hepatic, renal and gastric tumors occurred most frequently. Specific ascitis was detected in 25(48%), tumor pleuritis - in 11(15%) patients. BL of the facial skeleton, Waldeyer's ring, oro- and nasopharynx was in 12(17%) patients. Seven patients had concomitant involvement of the CNS. Eight (38%) and 2(10%) women had tumors of the ovaries and uterus, respectively. Conclusion. BL is characterized by the following clinical features: young age of the patients, most of them are males, B-symptoms, short history, generalized stages, extranodal lesions, frequent involvement of the bone marrow and CNS.
Mixed aluminum-containing metal-organic frameworks (MOF) modified with Fe, V, and Ti are synthesized in two steps. At the first step, the amorphous precursors of metal-organic frameworks containing ...various amounts of transition metals are obtained by the electrochemical method. At the second step, the precursors are crystallized under solvothermal conditions. Study of the effect of synthesis conditions shows that Fe-containing metal-organic frameworks crystallize in the presence of dimethylformamide; V- and Ti-containing counterparts crystallize in the presence of water. The time and temperature of crystallization are varied in the range from 150 to 200°С and 24 to 72 h depending on the concentration of the transition metals. The resulting samples are investigated by low-temperature nitrogen adsorption, scanning electron microscopy, X-ray powder diffraction, X-ray photoelectron spectroscopy, and thermogravimetric and differential thermal analysis (TGA-DTA). Research into the influence of catalyst composition on its activity in 1-octene epoxidation by
tert-
butyl hydroperoxide suggests that that the titanium-containing samples are catalytically inactive, while the vanadium-containing samples are more active than the iron-containing ones. Testing of the vanadium-containing samples in propylene epoxidation demonstrates that their activity is comparable with the activity of a commercial titanium silicate catalyst.
The aim was to investigate the association of monocyte heterogeneity and presence of circulating endothelial cells with the severity of coronary atherosclerosis in patients with coronary artery ...disease (CAD) and type 2 diabetes mellitus (T2DM). We recruited 62 patients with CAD, including 22 patients with DM2. The severity of atherosclerosis was evaluated using Gensini Score. Numbers of classical (CD14++CD16–), intermediate (CD14++CD16+), and non-classical (CD14+CD16++) monocyte subsets; circulating endothelial progenitor cells; and the presence of circulating endothelial cells were evaluated. Counts and frequencies of intermediate monocytes, but not glycaemia parameters, were associated with the severity of atherosclerosis in diabetic CAD patients (rs = 0.689; p = 0.001 and rs = 0.632; p = 0.002, respectively). Frequency of Tie2+ cells was lower in classical than in non-classical monocytes in CAD patients (p = 0.007), while in patients with association of CAD and T2DM, differences between Tie2+ monocytes subsets disappeared (p = 0.080). Circulating endothelial cells were determined in 100% of CAD+T2DM patients, and counts of CD14++CD16+ monocytes and concentration of TGF-β predicted the presence of circulating endothelial cells (sensitivity 92.3%; specificity 90.9%; AUC = 0.930). Thus, intermediate monocytes represent one of the key determinants of the appearance of circulating endothelial cells in all the patients with CAD, but are associated with the severity of atherosclerosis only in patients with association of CAD and T2DM.
BACKGROUND: The persistence and geographical expansion of leishmaniasis is a major public health problem that requires the development of effective integrated vector management strategies for sand ...fly control. Moreover, these strategies must be economically and environmentally sustainable approaches that can be modified based on the current knowledge of sand fly vector behavior. The efficacy of using attractive toxic sugar baits (ATSB) for sand fly control and the potential impacts of ATSB on non-target organisms in Morocco was investigated. METHODS: Sand fly field experiments were conducted in an agricultural area along the flood plain of the Ourika River. Six study sites (600 m x 600 m); three with “sugar rich” (with cactus hedges bearing countless ripe fruits) environments and three with “sugar poor” (green vegetation only suitable for plant tissue feeding) environments were selected to evaluate ATSB, containing the toxin, dinotefuran. ATSB applications were made either with bait stations or sprayed on non-flowering vegetation. Control sites were established in both sugar rich and sugar poor environments. Field studies evaluating feeding on vegetation treated with attractive (non-toxic) sugar baits (ASB) by non-target arthropods were conducted at both sites with red stained ASB applied to non-flowering vegetation, flowering vegetation, or on bait stations. RESULTS: At both the sites, a single application of ATSB either applied to vegetation or bait stations significantly reduced densities of both female and male sand flies (Phlebotomus papatasi and P. sergenti) for the five-week trial period. Sand fly populations were reduced by 82.8% and 76.9% at sugar poor sites having ATSB applied to vegetation or presented as a bait station, respectively and by 78.7% and 83.2%, respectively at sugar rich sites. The potential impact of ATSB on non-targets, if applied on green non-flowering vegetation and bait stations, was low for all non-target groups as only 1% and 0.7% were stained with non-toxic bait respectively when monitored after 24 hours. CONCLUSIONS: The results of this field study demonstrate ATSB effectively controls both female and male sand flies regardless of competing sugar sources. Furthermore, ATSB applied to foliar vegetation and on bait stations has low non-target impact.
Beltrami fields are complex vector fields
F
which satisfy the equation
curl
F
+
λ
F
=
0
.
Such fields appear in astrophysics, electromagnetics and plasma physics. We construct a complete system of ...solutions to the differential equation
(
D
+
λ
(
x
3
)
+
M
γ
(
x
3
)
e
3
)
u
=
0
for a complex quaternionic valued function
u
in a symmetric domain in
R
3
, by means of transmutation operators. We then apply this result to construct Beltrami fields, giving a complete system of fields when
λ
depends only on
x
3
.
The interaction of electromagnetic radiation with ordered and disordered arrays of noble metal nanoparticles, leading to the excitation of various modes of surface plasmon states in them, is ...analyzed. The dipole localized surface plasmon resonance in isolated nanoparticles and the influence of various size effects on its optical response are considered. The effect of dipole-dipole interaction between gold and silver nanoparticles on the optical properties of various nanosized and nanostructured objects is discussed. It is shown that both localized and delocalized (propagated) surface plasmon modes can be excited in composite gold and silver nanosystems, in particular, in porous films. The prospects for the practical application of nanostructures with arrays of gold and silver nanoparticles in sensor technology, surface-enhanced Raman spectroscopy, and modern optoelectronics are examined.
The spatio-temporal variability of the modern sedimentation process in Lake Onego, the second largest lake in Europe, was evaluated. The chemical composition of the lake water was studied. ...Sedimentation takes place in the oxidation conditions of low TDS water of the calcium bicarbonate type, where the ratio between terrigenous clastic material and lacustrine biochemical suspended matter in the material deposited to the bottom is close to one. We demonstrate that the sedimentation process in the lake is non-uniform. Sedimentation rates in different regions of the lake were estimated (0.1 to 2 kg per sq. m of bottom surface per year) through in situ surveys with sediment traps. Annual sediment input was estimated on the basis of the lake’s chemical balance. Analysis of the qualitative characteristics of the material deposited to the bottom shows its composition corresponds to the humus-Fe-Si type of sedimentation. The uniform texture and mineral composition and the similar multielement spectra of the sediments suggest that active water dynamics cause fine-grained suspended load to remain in the water column for prolonged time periods. Variations in the sediment chemical composition across the lake are due to natural causesand to unevenly distributed anthropogenic pressure.
Efficient methods to deposit thin layers of metal–organic frameworks (MOFs) are needed to integrate these microporous materials into microelectronics, sensing devices, and membranes. Herein, we ...report for the first time the direct aerosol jet printing of a MOF material. The ultramicroporous MOF Ca(C4O4) (H2O) (UTSA-280) was deposited from an aqueous precursor solution. In addition to blanket coatings, aerosol jet printing provides direct access to patterned coatings with a resolution of 100 μm via a digital, maskless approach. Moreover, by enabling spatial control over the layer thickness via the number of passes of the nozzle, this direct-write approach presents a more accessible alternative to advanced patterning techniques such as grayscale lithography.
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