The interaction of nickel(II) with halogenazomercaptophenols (HAMPs) {1-(5-bromo-2-pyridylazo)-2-hydroxy-4-mercaptophenol and 1-(5-iodo-2-pyridylazo)-2-hydroxy-4-mercaptophenol} in the presence of ...aminophenols (APs) 2,6-bis(N,N-dimethylaminomethyl)-4-methylphenol and 2,6-bis(N,N-dimethylaminomethyl)-4-ethylphenol was studied by the extraction-photometric method. The charge of the resultant complexes was determined by the methods of ion electromigration and electrophoresis on paper. Colored complexes proved to be anions. Upon introduction of the aminophenols into the system the anionic complexes passed into the organic phase in the form of mixed-ligand complexes (MLCs). A single extraction with chloroform provided a 97.1–98.9% yield of nickel(II) in the form of an MLC. The optimal range of acidity of the medium, corresponding to a maximal and constant absorbance, was pH
opt
2.4–6.5 (рH
form
0.7–8.4). The maximum absorbance was reached within 8–12 min. The optimal condition for the formation and extraction of these compounds were identified as HAMP concentration of (1.12–2.34)×10
–3
M and the AP concentration of (6.3–8.4)×10
–4
M. A 20-fold increase in the volume ratio of the aqueous to organic phase did not affect the completeness of the extraction. Light absorption was at a maximum at 605–648 nm. In the composition of the MLCs, there was one mole of HAMP and AP each per mole of nickel. Using the Nazarenko method, it was found that Ni
2+
is the complexing form of nickel. The number of protons it displaced from one H
2
L molecule turned out to be equal to 2. The performed calculations showed that the MLCs do not polymerize in the organic phase and occur in the monomeric form (γ = 0.94–1.07). The results of studies on the formation and extraction of MLCs of Ni(II) with HAMP and AP and the physicochemical and analytical characteristics of these compounds served as a basis for the development of new techniques for the extraction-photometric determination of Ni(II) in wastewater, bottom sediments, crude oil, and petroleum products of Baku.
The interest of consumers for diverse fermented foods has increased in recent years thanks to the positive perception of their impact on consumer health considered as beneficial. Hence, there is an ...evident need for search of novel ways and for new food preservation agents of natural origins. In this aspect, lactic acid bacteria are very good candidates. It should be highlighted also that the onset of food allergies is rising significantly in recent years. The reduction of the immunoreactivity of food proteins could be achieved thanks to pre-prandial proteolysis occurring in fermented dairy (and other food) systems changing the allergen presentation or cleaving the allergenic protein epitopes, and produce hypoallergenic products.
Abstract
The excitation of pygmy dipole resonance (PDR) and giant dipole resonance (GDR) in even–even
154–164
Dy isotopes is examined through quasiparticle random-phase approximation (QRPA) with the ...effective interactions that restore the broken translational and Galilean invariances. In each isotope, an electric response emerges by showing ample distribution at energies below and above 10 MeV. We, therefore, study the transition cross-sections and probabilities, photon strength functions, transition strengths, isospin character, and collectivity of the predicted E1 responses.
Cardiovascular toxicity of cancer therapies remains an urgent problem today. The creation of highly effect antitumor drugs also means the appearance of new adverse effects. Immune checkpoint ...inhibitors (ICI) is a new class of antitumor drugs that is different from traditional chemotherapeutic and targeted drugs. Immunotherapy with ICI (monoclonal antibodies targeting the cytotoxic T-lymphocyte associated antigen 4 (CTLA-4), programmed cell death protein 1 (PD-1) or its ligand (PD-L1)) significantly improved the results of treatment of cancer therapy. These drugs regulate antitumor immunity and promote cancer regression and improve survival, but can also cause a wide range of immunity-related adverse events (AEs). Although cardiotoxicity associated with ICI is rare, it is important because of its high mortality rates. In recent years, cases of myocarditis and fatal heart failure have been recorded more often in patients receiving ICI. This review focuses on the mechanisms of cardiotoxicity, methods for the prevention and treatment of these adverse events. Severe cardiovascular consequences associated with the use of ICI are important issues for oncologists, cardiologists and immunologists.
We here present a theoretical analysis of electric and magnetic dipole (
E
1 and
M
1) resonances in the
229
-
233
Th isotopes. In this study, the characteristic features of
M
1 and
E
1 excitations ...were calculated using the rotational invariant (RI-) and the translational Galilean invariant (TGI-) quasiparticle phonon nuclear models (QPNM), respectively.These models have been successfully applied to most rare-earth and actinide nuclei, with them yielding results that are consistent with the available experimental data.This study directly compares the TGI-QPNM results with experimental cross-section data (Oslo type; (
γ
,abs.)), and the model was found to reproduce the structural splitting of the
E
1 strength into two humps in the 8–20 MeV energy region.Furthermore, the study shows that the theoretical spectra of the
231
,
233
Th isotopes, whose giant dipole resonance (GDR) has not yet been measured, almost overlaps with the experimental GDR spectrum of the neighboring
232
Th nucleus.The predicted GDR parameters, such as peak energy, cross section, and width, are consistent with the experimental results. Our analysis also yields results that are similar to the corresponding parameters reported in the Oslo data for the PDR
E
1 (
ω
pyg
≈
7.2
MeV
;
σ
pyg
≈
10
mb
) and spin-flip M1 (
ω
M
1
≈
6.67
MeV
;
σ
M
1
≈
4.36
mb
) resonances.
In this study,
and
dipole mode excitations are systematically investigated within the rotational and translational + Galilean invariant quasiparticle random-phase approximation for
232
Th ,
236
U , ...and
238
U actinide nuclei. It is shown that the investigated nuclei reach a
B
(
M
1) strength structure, which corresponds to the scissors mode. The calculated mean excitation energies as well as the summed
B
(
M
1) value of the scissors mode excitations are consistent with the available experimental data. The results of calculations indicate large differences to the rare-earth nuclei as is the case for the experiment: a doubling of the observed dipole strengths and a shift of the energy centroid to the lower energies by about 800keV. The calculations indicate the presence of a few prominent negative-parity
states in the 2.0-4.0MeV energy interval. The occurrence of the negative-parity dipole states with the rather high
B
(
E
1) value less than 4MeV shows the necessity of explicit parity measurements for the correct determination of the scissors mode strength in
232
Th ,
236
U , and
238
U isotopes.
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