Abstract
The dynamics of a nuclear open quantum system could be revealed in the correlations between the breakup fragments of halo nuclei. The breakup mechanism of a proton halo nuclear system is of ...particular interest as the Coulomb polarization may play an important role, which, however, remains an open question. Here we use a highly efficient silicon detector array and measure the correlations between the breakup fragments of
8
B incident on
120
Sn at near-barrier energies. The energy and angular correlations can be explained by a fully quantum mechanical method based on the state-of-the-art continuum discretized coupled channel calculations. The results indicate that, compared to the neutron halo nucleus
6
He,
8
B presents distinctive reaction dynamics: the dominance of the elastic breakup. This breakup occurs mainly via the short-lived continuum states, almost exhausts the
7
Be yield, indicating the effect of Coulomb polarization on the proton halo state. The correlation information reveals that the prompt breakup mechanism dominates, occurring predominantly on the outgoing trajectory. We also show that, as a large environment, the continuum of
8
B breakup may not significantly influence elastic scattering and complete fusion.
Cancer is one of the leading causes of death worldwide, and Korea is no exception. Humanity has been fighting cancer for many years, and as a result, we now have effective treatments such as ...chemotherapy, radiation, and surgery. However, there are other issues that we are only now beginning to address, such as cancer patients’ quality of life. Moreover, numerous studies show that addressing these issues holistically is critical for overall cancer treatment and survival rates. This paper describes how Korea is attempting to reduce cancer incidence and recurrence rates while also managing the quality of life of cancer patients. Integrative Oncology is the field that addresses these broad issues, and understanding the current state of integrative oncology in Korea is critical. The goal of this paper is to provide an overview of the current state of integrative oncology in Korea as well as to look ahead to future developments.
A fast ionization chamber with a high counting rate was commissioned at the 8 MV tandem accelerator complex of Kyushu University in Japan. Heavy ion beams consisting of
12
C and
16
O with
E
beam
= ...36 MeV were used to investigate the detector performance. By using various beam intensities ranging from 10
3
to 10
6
particles per second (pps), the maximum counting rate of the ion counter was measured to be about 8 × 10
5
pps. The detector performance under different gases was also investigated using two common gases in the ionization chamber: isobutane and P-10 gases. The results show that the negative effects due to pileups, which are often observed at high counting rates, can be greatly reduced when P-10 gas is used.
Afatinib is a target anticancer drug of the second-generation EGFR TKI type, showing an advantage in treatment effect compared to conventional chemotherapy. However, patients on EGFR-TKI drugs also ...usually progress after 9 to 13 months according to secondary resistance. HAD-B1 is composed of drugs that are effective against lung cancer. This study is an exploratory study to evaluate the efficacy and safety between dosage groups by conducting a clinical trial in subjects requiring afatinib drug treatment in non-small cell lung cancer with EGFR mutation positive to determine the optimal dosage for HAD-B1 administration. At the final visit compared to before administration, each change in the disease control rate was measured according to the HAD-B1 doses of the test group 1 (972 mg), the test group 2 (1944 mg), and the control group. The efficacy and safety of HAD-B1 were compared and evaluated through sub-evaluation variables. As a result of the study, there was no statistically significant difference in the disease control rate at 12 weeks after dosing, but complete and partial remission were evaluated as 1 patient each in the test group 1, and none in the other groups. There was no statistically significant difference between groups in the sub-evaluation variable. In addition, there was no problem of safety from taking the test drug. However, the initially planned number of subjects was 66, but the number of enrolled subjects was only 14, which may limit the results of this study.
Transfer reaction measurements using SNACK at KoBRA Kwag, M.S.; Akers, C.; Lee, K.B. ...
Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms,
August 2023, 2023-08-00, Letnik:
541
Journal Article
Recenzirano
KoBRA can produce RI beams with energies of 5–10 MeV/u from stable ion beams (10–40 MeV/u) delivered from the superconducting linear accelerator SLC3 of RAON. In its early phase of operation, ...transfer reaction measurements with these RI beams can be performed for nuclear astrophysics studies. SNACK has been developed at RISP in order to measure the light ejectiles from the transfer reactions. With the beam trajectories obtained from upstream PPACs, excitation energy levels in the heavy recoils can be reconstructed by measuring light ejectile’s energies and scattering angles. The expected results of transfer reaction measurements with SNACK and KoBRA beamline detectors were calculated by using a Monte Carlo simulation.
.
We report on the development of a new, portable detector array for charged particles with a low detection threshold to study the reaction mechanisms of exotic nuclear systems at energies around the ...Coulomb barrier. In order to identify both light and heavy particles simultaneously, the array consists of ten units of
Δ
E
-
E
R
telescopes, where each one is made up of four detection layers: one ionization chamber, one 40 (or 60)μm double-sided silicon strip detector and two quadrant silicon detectors with thicknesses of 300μm and 1000 (or 1500)μm, respectively. The frame of the ionization chamber is innovatively designed with printed circuit boards, thus the mass of each telescopic unit was reduced significantly which eases transport and installation requirements to different radioactive ion beam lines around the globe. The commissioning experiments focused on elucidating several reaction mechanisms encountered in the
17
F +
58
Ni and
17
F +
208
Pb systems, and we demonstrated that the array has a sufficient capability to enable charged particle identification over a large range of
Z
. Light particles like
p
,
d
,
α
as well as heavy ions like
16
O and
17
F can be clearly distinguished. Considering these properties, this newly developed array enables in-depth investigation of the novel reaction mechanisms which are manifested in the collisions of exotic nuclei with differing isotopes.
Abstract
KoBRA of RAON has been prepared for various low energy nuclear physics studies such as nuclear structure, reactions, and astrophysics. An
α
-particle transport test was performed using a ...standard
α
-source of
241
Am so as to examine the design parameters. The position distribution of the
α
-particles was measured with a PPAC at the dispersive and achromatic focal planes, and compared with that of a
lise
++
Monte Carlo calculation. The results are consistent with each other, confirming a few design parameters. We report on the preliminary results of the
α
-particle transport test for KoBRA.
A 4-year prospective cohort study on patients with lung, gastric, hepatic, colorectal, breast, uterine, and ovarian cancer was conducted at the East-West Cancer Center (EWCC) of Daejeon Korean ...Medicine Hospital in Daejeon, Korea. We divided patients into 2 groups based on how long they had been receiving TKM oncotherapy and compared event-free survival (EFS), telomere length change, and quality of life (QoL). The study collected data on 83 patients from October 2016 to June 2020 and discovered no statistical differences in EFS based on the duration of TKM oncotherapy. In the analysis of changes in QoL outcomes, there were no statistically significant group differences between the groups. After controlling for covariates that could affect telomere length, the long-term TKM oncotherapy group had a higher daily telomere attrition rate. The study of the relationship between telomere length and prognostic factors discovered that patients with advanced N stage at the time of diagnosis and who had previously received radiotherapy had shorter telomere length. When examining associations between SNP genotype and percentile score of telomere length, this study was able to confirm an association between telomere length and rs4387287. This study is significant because it is the first to assess the effects of TKM oncotherapy and investigate telomere length-related factors. To assess the effects of TKM oncotherapy on cancer patients’ survival and QoL, a longer-term observational study with a larger sample size is required.
Studies on nuclear astrophysics, nuclear structure, and other interests have been performed using the radioactive-isotope (RI) beams at the low-energy RI beam separator CRIB, operated by Center for ...Nuclear Study (CNS), the University of Tokyo. The elastic resonant scattering is a striking tool to study astrophysical reactions and nuclear clusters. In particular, when it is coupled with a thick target and inverse kinematics, the measurement can be very efficient and even feasible with RI beams. By measuring resonant scattering, we can study the properties of resonant states which could play an important role in the astrophysical reaction, or have an exotic nuclear structure. The 10Be+α elastic scattering has been measured at CRIB, and three resonances which are in agreement with the prediction of a linear-chain structure by Suhara-En'yo were observed, giving a strong indication of the existence of such an exotic structure. Measurements based on the indirect technique of the reaction measurement, such as the Trojan horse method, have also been performed at CRIB.
PDF
