Context. Recently, the He I triplet at 10 830 Å was rediscovered as an excellent probe of the extended and possibly evaporating atmospheres of close-in transiting planets. This has already resulted ...in detections of this triplet in the atmospheres of a handful of planets, both from space and from the ground. However, while a strong signal is expected for the hot Jupiter HD 209458 b, only upper limits have been obtained so far. Aims. Our goal is to measure the helium excess absorption from HD 209458 b and assess the extended atmosphere of the planet and possible evaporation. Methods. We obtained new high-resolution spectral transit time-series of HD 209458 b using CARMENES at the 3.5 m Calar Alto telescope, targeting the He I triplet at 10 830 Å at a spectral resolving power of 80 400. The observed spectra were corrected for stellar absorption lines using out-of-transit data, for telluric absorption using the MOLECFIT software, and for the sky emission lines using simultaneous sky measurements through a second fibre. Results. We detect He I absorption at a level of 0.91 ± 0.10% (9 σ) at mid-transit. The absorption follows the radial velocity change of the planet during transit, unambiguously identifying the planet as the source of the absorption. The core of the absorption exhibits a net blueshift of 1.8 ± 1.3 km s−1. Possible low-level excess absorption is seen further blueward from the main absorption near the centre of the transit, which could be caused by an extended tail. However, this needs to be confirmed. Conclusions. Our results further support a close relation between the strength of planetary absorption in the helium triplet lines and the level of ionising, stellar X-ray, and extreme-UV irradiation.
Colorectal cancer in nonagenarians Arenal, J. J.; Tinoco, C.; Labarga, F. ...
Colorectal disease,
01/2012, Letnik:
14, Številka:
1
Journal Article
Recenzirano
Odprti dostop
Aim The aim of the study was to analyze the short‐term and long‐term outcomes of nonagenarians treated for colorectal cancer.
Method A retrospective analysis was performed of 74 patients, ≥ 90 ...years of age, diagnosed with colorectal cancer during the period 1986–2009. Comorbidity, American Society of Anesthesiology (ASA) grade, symptoms, diagnosis, treatment, mortality, morbidity and survival were analyzed.
Results Of the 74 patients, 48 (65%) were women. Twenty‐two patients were classified as ASA grade I–II, 26 as ASA grade III and 26 as ASA grade IV–V. Thirty‐one (42%) had intestinal obstruction at the time of diagnosis. Twenty‐two (30%) patients were diagnosed during the period 1986–2000 and 52 (70%) were diagnosed between 2001 and 2009. Forty‐four (59%) patients underwent surgery, of whom 19 (49%) were treated as an emergency. Eleven (25%) patients died postoperatively, with mortality rates of 12% (3/25) for elective surgery and 42% (8/19) for emergency surgery. Surgical mortality for ASA grade I and grade II patients was 5% (1/20) and their 5‐year survival rate (postoperative mortality excluded) was 44%, whereas 5‐year survival for ASA grade III patients who underwent surgery was 12.5% and surgical mortality was 25% (4/16). There were no survivors beyond 36 months among patients who did not receive surgery.
Conclusion Our results indicate that elective and emergency colorectal surgery can be performed with acceptable rates of mortality and morbidity on nonagenarian patients in good general condition with low perioperative risk. The 5‐year survival rate was related to ASA grade and to the use of surgery.
Abstract Objectives We sought to evaluate our transplant series in light of the parameters outlined in the quality criteria established by the Spanish Hepatic Transplant Society (Sociedad Española de ...Trasplante Hepático SETH). Methods We retrospectively analyzed 240 hepatic transplantations performed in 223 patients from November 2001 to December 2009. Results Among the series, 57% were in Child class C, 50% had cirrhosis without hepatocellular carcinoma, and 32% had this neoplasm. The most common cause for the illness was alcohol, followed by a virus, namely hepatitis C virus in 76% of cases. The average waiting list time was 45.14 days. The total graft ischemia averaged 460 minutes (range, 265–937). The 4.1% ( n = 10), incidence of an urgent retransplantation was mainly due to primary graft failure or arterial thrombosis. During the perioperative period the mortality rate was 2.5% ( n = 6) and the 1-month mortality rate was 6.6% ( n = 16). The raw survival rates at 1, 3, and 5 years after the operation are 85%, 78%, and 72%, respectively. Conclusion Our perioperative as well as the long-term results fall within the quality standards established by SETH.
The local hadronic calibration scheme developed for the reconstruction and calibration of jets and missing transverse energy in ATLAS has been evaluated using data obtained during combined beam tests ...of modules of the ATLAS liquid argon endcap and forward calorimeters. These tests covered the pseudorapidity range of 2.5 < | ? | < 4.0 . The analysis has been performed using special sets of calibration weights and corrections obtained with the Geant4 simulation of a detailed beam-test setup. The evaluation itself has been performed through the careful study of specific calorimeter performance parameters such as e.g. energy response and resolution, shower shapes, as well as different physics lists of the Geant4 simulation.
Abstract Background Some variations of hepatic artery, which show 30% incidence, must be taken into account to avoid damage to the liver transplant during harvesting, we analyzed the incidence of ...variations and their influence on postoperative results. Patients and methods We performed a retrospective study of 325 liver transplantation between 2001 and December 2011. Results Variations in the hepatic artery were detected in 91 transplantations (32%) including 29 donors (8.9%), 57 recipients (17.5%), and 5 both (1.5%). The main variation among donors was a right hepatic artery originating from the mesenteric artery (38.2%), and a left hepatic artery from the left gastric artery (35.3%). Recipients showed the same distribution: RHA-UMA (right hepatic artery from upper mesenteric artery) (38.7%) and LHA-LGA (left hepatic artery from left gastric artery) (12.9%). 48.5% of donor hepatic variations did not need bench reconstruction, but all RHA-UMA required it mainly due to the donor gastroduodenal artery (7; 58%) We did not observe significant difference in cold or warm ischemia time, surgical time, red blood cell requirement, postoperative mortality, or overall survival when there was or was not an arterial anomaly. But arterial complications were more frequent in cases where there were recipient anomalies or both versus without anomalies or with donor anomalies (20%, 7,8%, 0%, 5,6%; P = .06). Donor RHA-UMA was associated with worse overall survival (69, 2%; P = .07) and longer cold ischemia time and red blood requirement. Bench reconstruction held to longer cold ischemia time and blood cell requirements ( P = .01) and shorter overall survival (82.4%). RHA-UMA was associated ( P = .08) with worse actuarial survival and a needed for bench reconstruction ( P = .01). Conclusion One must be careful during liver harvest to detect hepatic artery variations to avoid damage. Hepatic artery anomalies do not influence liver transplant results except for the presence of an RHA from the UMA with a need for bench reconstruction.