•The patient with an SLC6A1 mutation, typically linked to disorders like epilepsy and autism, exhibited symptoms consistent with schizophrenia and bipolar disorder.•The patient's polygenic risk score ...was aligned with both schizophrenia and bipolar disorder, despite no family history of psychiatric disorders.•The study contributed to ongoing discussion of the importance of GABAergic processes in schizophrenia's etiology.
В настоящее в российском законодательстве отсутствуют, какие-либо нормы, регулирующие распространение и использования дипфейков, в научной литературе имеются совершенно полярные точки зрения на ...необходимость подобного регулирования. Таким образом, в работе поднимается вопрос о необходимости адаптации существующих механизмов правового регулирования с учётом активного развития технологий искусственного интеллекта. В работе авторами предлагается авторская формулировка понятия «дипфейк», описаны угрозы их применения (как потенциальные, так и реальные), а также предлагается видовая и типовая классификация дипфейков. По результатам исследования делается вывод о необходимости проработки механизмов предупреждения использования и распространения дипфейков, например, закрепив нормативно определение «дипфейка», вводя нормы об обязательной маркировке дипфейков и использовании водяных знаков при их создании.
Katyn Materski, Wojciech; Cienciala, Anna M; Lebedeva, Natalia S
01/2008
eBook
The 14,500 Polish army officers, police, gendarmes, and civilians taken prisoner by the Red Army when it invaded eastern Poland in September 1939 were held in three special NKVD camps and executed at ...three different sites in spring 1940, of which the one in Katyn Forest is the most famous. Another 7,300 prisoners held in NKVD jails in Ukraine and Belarus were also shot at this time, although many others disappeared without trace. The murder of these Poles is among the most monstrous mass murders undertaken by any modern government.
Three leading historians of the NKVD massacres of Polish prisoners of war at Katyn, Kharkov, and Tver-now subsumed under "Katyn"-present 122 documents selected from the published Russian and Polish volumes coedited by Natalia S. Lebedeva and Wojciech Materski. The documents, with introductions and notes by Anna M. Cienciala, detail the Soviet killings, the elaborate cover-up, the admission of the truth, and the Katyn question in Soviet/Russian-Polish relations up to the present.
The paper assesses possibilities of the use of data obtained at the Mogot trail ground located at the Souther boundary of the Baikal-Amur Railway permafrost zone in the Zeaya River upstream for the ...purposes of determining of the «Gidrograf» determinated hydrological model to be used in simulating of water balance and runoff characteristics of non-investigated rivers. Sets of the hydrological model parameters depicting typical landscapes of the region under investigation have been developed. The verification of them has been performed on the basis of the data obtained at the Mogot ground concerning evaporation from the snow surface and soil/vegetation layer in different landscapes, water content in snow blanket, soil temperature at different depths, values of the soil/ground thaw through and frost through and the observed daily hydrographs of small rivers water runoff. Satisfactory results were obtained at small catchments of the trail ground including variable states, water balance and small rivers water runoff at the Mogot ground (3–30.8 km2) over the 1976–1985 period. Representativity of the obtained set of parameters has been assessed for non-investigated catchments of the Tynda and Unakha rivers (4060 and 1950 km2). The results of non-stop modeling over the 1966–2012 period for the Tynda and Unakha rivers prove principal possibility of the further use of the set of the developed parameters and the «Gidrograf» hydrological model for simulating of the region under investigation rivers runoff.
The effects of nootropic drug Semax on the neuronal network of the brain were studied by the resting state functional magnetic-resonance imaging (resting state fMRI). The study was carried out on two ...groups of healthy volunteers (11 men and 13 women aged 43.9±9.5 years). Resting state fMRI was carried out 3 times: directly before and 5 and 20 min after intranasal 1% Semax (14 subjects) or placebo (10 subjects). The topography of the resting state default mode network was studied. A greater volume of the default mode network rostral (medial frontal cortex) subcomponent was detected in the Semax group in comparison with controls. Resting state fMRI confirmed Semax effects on the neuronal network of the brain and demonstrated topography of these effects.
Based on the analysis of more than 17,000 vegetation plots (relevés), the participation of 261 protected species (254 vascular plants, six lichens, and one bryophyte) in 30 EUNIS grassland habitat ...types was revealed. Vegetation plots were assigned to the habitat types using the EUNIS-ESy expert system with further verification. We consider as protected species those listed in the current edition of the Red Data Book of Ukraine, Resolution 6 of the Bern Convention, Annexes II and IV of the Habitat Directive, and the IUCN Red List (only categories VU, EN, CR). The participation of protected species was studied according to the following three criteria: (1) the total number of protected species in the plots assigned to a certain habitat type, (2) the number of plots in which at least one protected species is present, and (3) the mean number of protected species per plots within each habitat type. True steppes (R1B) and meadow steppes (R1A) differed with a significant predominance of the total number of protected species. Arctic alpine calcareous grassland (R44) and Continental dry rocky steppic grassland and dwarf scrub on chalk outcrops (R15) had the largest proportion of plots with protected species and the highest mean numbers of protected species per relevé. Saline habitats, in particular Temperate inland salt marsh (R63) and Semi desert salt pan (R64), were characterized by the smallest number of plots with protected species. Among all species, Gymnadenia conopsea, Stipa capillata, Colchicum autumnale and Gladiolus imbricatus occurred in the largest number of studied habitat types. Based on the results of the analysis, appropriate ways of optimizing the protection of grassland habitats and protected species are proposed.
Personal protective equipment has become the last line of protection for medical personnel during the pandemic of the new coronavirus infection since it allows minimizing risks of biological ...contagion. Given the existing staffing shortage, medical workers have to spend from 4 to 12 hours a day in the “red zone” where they necessarily wear personal protective equipment. Protective clothing is known to produce negative effects on functional state of the body and personnel’s working capacities. Assessment of up-to-date protective suits will allow developing recommendations on their suitable application bearing in mind a balance between necessary protection, providing favorable ergonomics, and reducing risks of adverse effects on functional state and working capacities. Our research aim was to hygienically assess health risks for medical workers who had to wear reusable protective suits. Our research object was a reusable suit made from polyether fabric with polyurethane membrane coating and antistatic threads. We performed an experiment aimed at evaluating thermal state of the body, psychophysiological state, and responses by the volunteers’ cardiorespiratory system in laboratory conditions during an 80 hour working shift under controlled microclimate. Participants in the experiment were questioned in order to assess suits’ ergonomics. Heat exchange dynamics and amount of changes in thermal physiological parameters caused by wearing a protective suit determined heat contents of volunteers’ bodies that conformed to optimal standard values. Data on psychophysiological and mental state taken in research dynamics didn’t have any statistically significant changes. Gas exchange indicators naturally grew during the “load” phase; however, there were no significant changes detected in any phase in the research. Hygienic assessment of the thermal state, functional state of the cardiovascular and respiratory systems, and psychophysio-logical indicators confirmed that wearing a protective suit was quite safe and didn’t involve any health risks for volunteers.
Personal protective equipment has become the last line of protection for medical personnel during the pandemic of the new coronavirus infection since it allows minimizing risks of biological ...contagion. Given the existing staffing shortage, medical workers have to spend from 4 to 12 hours a day in the “red zone” where they necessarily wear personal protective equipment. Protective clothing is known to produce negative effects on functional state of the body and personnel’s working capacities. Assessment of up-to-date protective suits will allow developing recommendations on their suitable application bearing in mind a balance between necessary protection, providing favorable ergonomics, and reducing risks of adverse effects on functional state and working capacities. Our research aim was to hygienically assess health risks for medical workers who had to wear reusable protective suits. Our research object was a reusable suit made from polyether fabric with polyurethane membrane coating and antistatic threads. We performed an experiment aimed at evaluating thermal state of the body, psychophysiological state, and responses by the volunteers’ cardiorespiratory system in laboratory conditions during an 80 hour working shift under controlled microclimate. Participants in the experiment were questioned in order to assess suits’ ergonomics. Heat exchange dynamics and amount of changes in thermal physiological parameters caused by wearing a protective suit determined heat contents of volunteers’ bodies that conformed to optimal standard values. Data on psychophysiological and mental state taken in research dynamics didn’t have any statistically significant changes. Gas exchange indicators naturally grew during the “load” phase; however, there were no significant changes detected in any phase in the research. Hygienic assessment of the thermal state, functional state of the cardiovascular and respiratory systems, and psychophysio-logical indicators confirmed that wearing a protective suit was quite safe and didn’t involve any health risks for volunteers.
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