In Korea, green remodeling of public buildings will be mandatory from 2025, and about 30,000 old public buildings nationwide will conduct green remodeling every year. Therefore, in this study, green ...remodeling was promoted to improve energy efficiency for existing public buildings located in Siheung, Gyeonggi-do. A remodeling method was developed to reduce the cooling and heating load of the building and reduce construction costs. The development technology was applied to the demonstration building to improve the insulation and airtightness performance of the building. In order to analyze the effect of improving the energy performance of the building, the simulation results and energy consumption before and after remodeling were analyzed. The demand for heating energy decreased by about 68.95%, and the demand for cooling energy decreased by 35.21%. According to an analysis of actual energy consumption, the average monthly energy consumption savings from January to September was 17.4%. It was confirmed that the savings were the highest at 35.4% in February, during winter. Applying the remodeling method developed in this study is expected to contribute to reducing greenhouse gas emissions by reducing energy efficiency and energy consumption of existing buildings.
A mechanically and thermally stable and electron-selective ZnO/CH3NH3PbI3 interface is created via hybridization of a polar insulating polymer, poly(ethylene glycol) (PEG), into ZnO nanoparticles ...(NPs). PEG successfully passivates the oxygen defects on ZnO and prevents direct contact between CH3NH3PbI3 and defects on ZnO. A uniform CH3NH3PbI3 film is formed on a soft ZnO:PEG layer after dispersion of the residual stress from the volume expansion during CH3NH3PbI3 conversion. PEG also increases the work of adhesion of the CH3NH3PbI3 film on the ZnO:PEG layer and holds the CH3NH3PbI3 film with hydrogen bonding. Furthermore, PEG tailors the interfacial electronic structure of ZnO, reducing the electron affinity of ZnO. As a result, a selective electron-collection cathode is formed with a reduced electron affinity and a deep-lying valence band of ZnO, which significantly enhances the carrier lifetime (473 μs) and photovoltaic performance (15.5%). The mechanically and electrically durable ZnO:PEG/CH3NH3PbI3 interface maintains the sustainable performance of the solar cells over 1 year. A soft and durable cathodic interface via PEG hybridization in a ZnO layer is an effective strategy toward flexible electronics and commercialization of the perovskite solar cells.
Efficient charge transfer between organic semiconductors and electrode materials at electrode interfaces is essential for achieving high-performance organic optoelectronic devices. For efficient ...charge injection and extraction at the electrode interface, an interlayer is usually introduced between the organic active layer and electrode. Here, a simple and effective approach for further improving charge transfer at the organic active layer–interlayer interface was presented. Treatment of the zinc oxide (ZnO) interlayer, a commonly used n-type interlayer, with a fullerene-based self-assembled monolayer (SAM) effectively improved electron transfer at the organic–ZnO interface, without affecting the morphology and crystalline structure of the organic active layer on the cathode interlayer. Furthermore, this treatment reduced charge recombination in the device, attributed to the improved charge extraction and reduction of undesirable ZnO-donor polymer contacts. The photocurrent density and power conversion efficiency of organic solar cells employing the fullerene-SAM-treated interlayer were ~10% higher than those of the device employing the nontreated interlayer. This improvement arises from the enhanced electron extraction and reduced charge recombination.
Herein we report a comparative morphological analysis of the perylene diimide (PDI)- and fullerene-based organic solar cells (OSCs) to identify the factors responsible for low performance of ...PDI-based devices. A PDI derivative, bis-PDI, and a fullerene derivative, PC
BM, are mixed with an efficient polymer donor, PffBT4T-2OD. The large disparity in power conversion efficiencies (PCEs) of OSCs composed of PffBT4T-2OD:bis-PDI (PCE = 5.18%) and PffBT4T-2OD:PC
BM (PCE = 10.19%) observed are attributed to differences in the nanostructural motif of bulk heterojunction (BHJ) morphologies of these blend systems. The X-ray scattering and surface energy characterizations revealed that the structurally dissimilar bis-PDI and PC
BM molecules determine the variation in blend film morphologies, and in particular, the molecular packing features of the donor PffBT4T-2OD polymer. In addition, high-resolution transmission electron microscopy (HRTEM) images explore the BHJ morphologies and presence of longer polymer fibrils in PffBT4T-2OD:bis-PDI system, justifying the unbalanced charge transport and high hole mobility. The low performance of PffBT4T-2OD:bis-PDI devices was further investigated by studying charge carrier recombination dynamics by using light-intensity-dependent and transient photovoltage (TPV) experiments. Furthermore, the temperature-dependent experiments showed the photovoltaic properties, including charge recombination losses, are strongly affected by energetic disorder present in bis-PDI-based system.
This meta-analysis synthesized the effects of the English medium instruction and content and language integrated learning (EMI-CLIL) approach on secondary-level students’ English learning. The ...dataset included 44 samples (N = 7,434) from 38 primary studies. The results revealed EMI-CLIL’s overall effectiveness for the development of English competence compared to the mainstream condition in the short term (d = 0.73, SE = 0.06, 95% CI 0.61, 0.86) and longer term (d = 1.01, SE = 0.06, 95% CI 0.88, 1.15). Additionally, we found that EMI-CLIL’s overall effectiveness was influenced by several moderator variables. Its effectiveness was significantly: (1) higher for learners whose first language (L1) was linguistically related to English; (2) lower for primary studies which confirmed the homogeneity of the EMI-CLIL and comparison groups; (3) lower when studies targeted the productive (rather than receptive or overall) dimension of English learning; and (4) higher when outcome measures focused on vocabulary. Implications for pedagogy and future research are discussed.
SMC condensin complexes are central modulators of chromosome superstructure in all branches of life. Their SMC subunits form a long intramolecular coiled coil, which connects a constitutive “hinge” ...dimerization domain with an ATP-regulated “head” dimerization module. Here, we address the structural arrangement of the long coiled coils in SMC complexes. We unequivocally show that prokaryotic Smc-ScpAB, eukaryotic condensin, and possibly also cohesin form rod-like structures, with their coiled coils being closely juxtaposed and accurately anchored to the hinge. Upon ATP-induced binding of DNA to the hinge, however, Smc switches to a more open configuration. Our data suggest that a long-distance structural transition is transmitted from the Smc head domains to regulate Smc-ScpAB’s association with DNA. These findings uncover a conserved architectural theme in SMC complexes, provide a mechanistic basis for Smc’s dynamic engagement with chromosomes, and offer a molecular explanation for defects in Cornelia de Lange syndrome.
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•Prokaryotic Smc-ScpAB complexes form rod-like structures•Binding of ATP and DNA induces a rod-to-ring transition in prokaryotic condensin•The condensin hinge is rigidly anchored to its coiled coil•The rod-like conformation is a conserved feature of SMC protein dimers
Soh et al. show that the rod-like conformation is a conserved architectural scheme of SMC complexes. Upon ATP-induced binding to DNA, the juxtaposed coiled coils of prokaryotic Smc-ScpAB adopt an open conformation to expose a DNA binding site at the inner surface of the hinge domain.
Purpose We investigate the clinicopathological features and prognostic significance of visceral obesity in patients with localized renal cell carcinoma. Materials and Methods This study included 706 ...patients with localized renal cell carcinoma who had undergone curative surgery between January 2003 and April 2012. Visceral, subcutaneous and total adipose tissue were measured based on preoperative computerized tomography of the umbilical region. Visceral adipose tissue percent was calculated using the formula, VAT% = visceral adipose tissue/total adipose tissue × 100. The association between clinicopathological factors and visceral obesity was examined. Results A higher VAT% at diagnosis was associated with older age at diagnosis, higher prevalence of diabetes and higher prevalence of former or current smoking status. The distribution of histological subtypes differed significantly among VAT% quartiles. The proportion of high grade tumors increased as VAT% increased (OR 1.023, 95% CI 1.000–1.126, p = 0.037). A U-shaped association between VAT% quartiles and the risk of disease recurrence was observed for all patients. Disease recurrence was significantly increased in the lowest (HR 3.198, 95% CI 1.765–10.040, p = 0.036) and highest (HR 4.760, 95% CI 2.937–13.210, p = 0.010) VAT% quartiles. Conclusions Relative visceral obesity as assessed by VAT% was associated with clinicopathological characteristics of localized renal cell carcinoma. A U-shaped association between VAT% quartiles and risk of disease recurrence was observed among patients with localized renal cell carcinoma.
The purpose of this study is to investigate the relationship between pay disparity and a company’s investment inefficiency, and to explore the moderating influence of investment in internal control ...personnel on this relationship. The global concern over pay disparity has intensified as executive compensation soars to unparalleled heights, while employee wages remain static. Utilizing a fixed-effect regression model and analyzing 5,407 observations from Korean listed companies between 2018 and 2020, the study shows a positive association between pay disparity (coef = 0.034, p-value < 0.01) and investment inefficiency, with pay disparity increasing the level of investment inefficiency by fostering overinvestment. Furthermore, the study shows that the interaction term between pay disparity and quantitative (coef = –0.246, p-value < 0.01) and qualitative (coef = –2.104, p-value < 0.01) investments in internal control personnel is negative and significant, indicating that the positive link between pay disparity and investment inefficiency is lessened when there is a higher quantitative and qualitative investment in internal control personnel. By offering a more comprehensive understanding of the conflicting evidence about the impact of pay disparity and the role of investment in internal control personnel in moderating the negative effect of pay disparity on investment efficiency, this study contributes to the existing literature. The findings of the study suggest that companies aiming to minimize investment inefficiency should consider not only addressing pay disparity but also investing in internal control personnel.
Although internal control systems in firms aim to provide reasonable assurance regarding objectives related to operations, reporting, and compliance, research focusing on operational efficiency is ...limited. This study investigates the impact of both quantitative and qualitative investments in internal control personnel on a firm’s operational efficiency. Utilizing a fixed-effect regression model, the Heckman (1979) two-stage model, and a two-stage least squares procedure, this study analyzes 4,471 firm-year observations from Korean listed firms from 2018 to 2020. The findings indicate a positive association between investment in internal control personnel and operational efficiency. This relationship remains robust even under sensitivity tests and concerns of potential endogeneity, as confirmed by the Heckman and two-stage least squares models. Specifically, the Heckman model shows that the ratio of the number of employees (coef = 0.023, t-value = 5.20) and certified public accountants (coef = 0.256, t-value = 5.43) responsible for internal control is positively associated with operational efficiency. Average work experience (coef = 0.002, t-value = 1.84) of internal control personnel is also positively related to operational efficiency. This study provides empirical evidence for the significance of investing in internal control personnel to boost operational efficiency and suggests that firms should consider both quantitative and qualitative aspects of internal control.
Despite advances in resolving the structures of multi-pass membrane proteins, little is known about the native folding pathways of these complex structures. Using single-molecule magnetic tweezers, ...we here report a folding pathway of purified human glucose transporter 3 (GLUT3) reconstituted within synthetic lipid bilayers. The N-terminal major facilitator superfamily (MFS) fold strictly forms first, serving as a structural template for its C-terminal counterpart. We found polar residues comprising the conduit for glucose molecules present major folding challenges. The endoplasmic reticulum membrane protein complex facilitates insertion of these hydrophilic transmembrane helices, thrusting GLUT3's microstate sampling toward folded structures. Final assembly between the N- and C-terminal MFS folds depends on specific lipids that ease desolvation of the lipid shells surrounding the domain interfaces. Sequence analysis suggests that this asymmetric folding propensity across the N- and C-terminal MFS folds prevails for metazoan sugar porters, revealing evolutionary conflicts between foldability and functionality faced by many multi-pass membrane proteins.
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