Aim. To assess the secondary prevention in Russian patients with coronary artery disease in the long-term period after acute myocardial infarction, acute coronary syndrome (ACS), percutaneous ...coronary intervention and/or coronary artery bypass grafting, obtained in the European Action on Secondary and Primary Prevention by Intervention to Reduce Events (EUROASPIRE V) survey in comparison with the general population of the study.Material and methods. EUROASPIRE V is a cross-sectional study with 27 countries, including Russia, which involved patients with ACS or indications for myocardial revascularization. At participating centers, patients admitted to hospital due to ACS or for percutaneous coronary intervention or coronary artery bypass grafting were identified. After 6 months and <2 years after discharge, patients were examined.Results. In total, 699 patients were identified in Russia, 399 of which visit an interview (women, 27,1%; mean age, 62,8±8,7 years). In the general population of the study, 16,208 patients were identified, 8,261 of which were interviewed (women, 25,8%; mean age, 63,6±9.6 years). At the time of the interview, 18,5% of Russian patients continued to smoke (16,8% in the general study population), the prevalence of overweight or obesity – 85,4 and 81,7%, abdominal obesity – 60,4 and 58,5%, diabetes – 21,9 and 29,3% of patients, respectively. In 19,7 and 16,4% of patients, respectively, diabetes was first diagnosed with a glucose tolerance test in the study. The target glycated hemoglobin was achieved in 47,1 and 54,4%, blood pressure – in 64,0 and 53,7%, low-density lipoprotein cholesterol – in 27,6 and 29,0% of patients, respectively.Conclusion. There were significant differences between the Russian cohort and the general study population. Some key secondary prevention parameters were more favorable in the Russian cohort, and some parameters – in the general group. In both compared populations, significant reserves are retained for further optimization.
Aim. Analysis of psychosocial risk factors in coronary heart disease (CHD) patients among Russian centers of the EUROASPIRE IV study, comparing to overall study population.Material and methods. In ...the cross-sectional study, 24 European countries participated, including Russian Federation (3 centers). In the study, patients were included of the age 18-80 y.o., who, during the period ≥6 months to <3 years before the inclusion, had been hospitalized with myocardial infarction (MI) or other acute coronary syndromes (ACS) or for myocardial revascularization. To the study protocol, the analysis of medical charts was included, with following visit and structured interview. During the study, long-term results were evaluated, presence and level of the risk factors, including psychosocial, life quality parameters, adequacy of the acquired by patients recommendations and the grade of adherence. Prevalence of anxiety and depression symptoms was assessed with the Hospital Anxiety and Depression Scale (HADS).Results. Overall, in the Russian centers, 746 patients were included, of those to the interview visit 424 admitted (mean age 63,4±9,0 y.o., 25,2% females). Educational level of the Russian cohort was higher than of overall study population (higher education in 44,3% and 22,3%, respectively). Prevalence of the anxiety symptoms in Russian patients and in overall population almost matched: 8-10 points by HADS-A in Russia and overall had 15,7% and 15,0% of participants, respectively, the ≥11 points — 12,4% and 11,3%, respectively. Contrary, the prevalence of depression symptoms in Russia was slightly higher: 8-10 by HADS had 16,4% and 14,6%, and ≥11 — 10,9% and 7,8%, respectively. Both anxiety and depression symptoms were more common among women; depression symptoms were more common for post-MI/ ACS patients than in the re-vascularized.Conclusion. By the data from European monitoring center of EUROASPIRE IV, in Russian cohort of CHD post MI/ACS, and revascularized patients there are specific differences in comparison with overall study population in psychosocial risk factors. Prevalence of clinically significant anxiety and depression symptoms in Russian cohort of EUROASPIRE IV was significantly lower than in earlier trials, including EUROASPIRE III, and was just slightly higher than in overall study population.
The picture of primary prevention obtained from real-life practice makes possible scheduling measures for prevention improvement.
To analyze features of drug and non-drug therapy aimed at decreasing ...cardiovascular risk in Russian patients with a high risk (HR) of CVD compared with the study general population.
14 European countries, including the Russian Federation, participated in this cross-sectional study. The study included patients aged 18-80 without clinical signs of atherosclerosis who have received antihypertensive and/or lipid-lowering therapy and/or therapy for diabetes mellitus (DM) within >6 to.
Evaluation of the effectiveness of risk management in persons with high cardiovascular risk is an important element in reducing the death rate of the population from cardiovascular diseases (CVD).
...Analysis of the prevalence and level of risk factors control in patients with high CV risk CVD from the Russian centers of the primary care unit of the EUROASPIRE IV study in comparison with the general population of the study.
In this cross-sectional study, 14 European countries, including the Russian Federation, participated. Patients aged 18 to 79 years were included in the study, without clinical manifestations of atherosclerosis, who were prescribed antihypertensive therapy and/or lipid lowering therapy and/or treatment for diabetes between the ages of ≥6 months and.
High precision mass measurements in
Ψ and
ϒ families performed in 1980–1984 at the VEPP-4 collider with OLYA and MD-1 detectors are revisited. The corrections for the new value of the electron mass ...are presented. The effect of the updated radiative corrections has been calculated for the
J/
Ψ(1
S) and
Ψ(2
S) mass measurements.
Status of the KEDR detector Anashin, V.V; Aulchenko, V.M; Baibusinov, B.O ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
02/2002, Letnik:
478, Številka:
1
Journal Article
Recenzirano
KEDR is a general-purpose detector for experiments at the VEPP-4M e
+e
−-collider in the energy range 2
E=2.0–
12
GeV
. All detector subsystems (except the aerogel Cherenkov counters) have been ...installed into the detector at VEPP-4M. Some preliminary data have been taken in the energy region of the J/Ψ meson. The tuning of the detector and the VEPP-4M collider is in progress. Preliminary results on the detector performance are presented. The future experimental program for the KEDR detector is discussed.
Aim.
High-sensitive C-reactive protein (hsCRP) is currently regarded as an important marker of cardiovascular disease (CVD). The aim of the study was to assess the population characteristics of hsCRP ...in the sample of Moscow residents aged 55 years and older.
Material and methods.
The analysis included 1851 people (response rate 65 %), who participated in the SAHR (Stress, Aging, and Health in Russia) study.
Results.
The hsCRP levels were similar in men and women, with the right-skewed distribution. The hsCRP values ranged from 0,5 to 69,5 mg/dl in men (median 1,5 mg/l), and from 0,5 to 75 mg/l in women (median 1,5 mg/l). The mean hsCRP levels were slightly higher in men than in women (3,4±0,19 vs. 3,1±0,15, respectively;
р
=0,36). Overall, there was no marked age-related dynamics of hsCRP levels in men or women. The prevalence of high hsCRP levels (>3 mg/l) non-significantly increased from 31,2 % in the youngest age group to 36,2 % in those aged 75 years and older. Acute inflammation (hsCRP levels >10 mg/l) was registered in 85 participants (4,5 %), including 42 men and 43 women. After adjustment for age and gender, the lower education level remained a significant predictor of hsCRP elevation.
Conclusion.
No clear associations between hsCRP and age or gender were observed. However, participants with university and secondary education had significantly lower hsCRP concentrations, compared to their peers with education level lower than secondary.
Aim. To study prevalence of risk factors (RF), target organ damage (TOD), and associated clinical conditions (ACC) in arterial hypertension (AH) patients, for total cardiovascular risk assessment. ...Material and methods. Epidemiological AH survey including 3661 males and 6334 males, aged 15+ years, from a representative national sample, was performed as part of the Program «AH Prevention and Treatment in the Russian Federation». Results. AH males, comparing to hypertensive females, had lower education level, smoked and drunk alcohol excessively more often (48.3% vs 7.9%; 6.8% vs 1.9%, respectively). In females, obesity prevalence was higher: 34.9% vs 18.1% in males. One-fifth of hypertensive patients had hypertensive retinopathy, 41% - left ventricular hypertrophy. Coronary heart disease (CHD) prevalence was higher in males - 22.3% vs 17.6% in females; the prevalence of other ACC was similar in both genders. In females, Stage III AH was diagnosed more often: 6.3% vs 4.2% in males. Antihypertensive therapy was administered to 59.5% of males and 73.8% of females, but treatment effectiveness was low – 12.9% and 13.5%, respectively. In untreated hypertensive patients, very high risk was typical for women (6.0% vs 3.9% in men); in treated patients, more than 80% remained in high and very high risk groups. Conclusion. In AH individuals, RF, TOD, and ACC, as well as poor BP control, are prevalent, that explained high risk level for the majority of patients.
The article is devoted to methodical recommendations on sample selection in regions with varying population size; representativeness assessment criteria; standard diagnostic methods for arterial ...hypertension (AH), risk factors, target organ status, and concomitant pathology; total cardiovascular risk assessment, as a part of the Target Federal Program «Arterial hypertension prevention and treatment in Russian Federation, 2002-2008».
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