Abstract-A rectangular array of seismic nodes is called a 3D seismic sensors array which is suitable for geographic routing. However, when certain seismic nodes have no location information, using ...detours or other methods to detect the path will increase latency and power consumption of geographic routing. It is challenging to maintain the high performance of geographic routing in practical 3D exploration networks. This letter proposes a greedy flee in the direction routing algorithm (GFDR). According to the feature that the intersection of the connection set of nodes is not empty, GFDR can drive the packet continuously forward in a specified direction without location information when the packet records the node ID of the path. Simulation results show that as the size of the area without location information (AWLI) increases, GFDR can keep the delivery ratio above 98%, while maintaining an approximately constant packet delay without increasing the number of packet-forwarding hops. A real seismic system experiment running GFDR algorithm confirms the simulation results and demonstrates the effectiveness of GFDR.
In this study, the two-phase flow coordination characteristics between α and β phases of H62 brass made by up-drawing continuous casting are investigated based on the upsetting process. An in situ ...and new research method for two-phase flow is put forward, and the two-phase flow and grain refinement characteristics are observed under different deformation conditions. The results show that α phase flows fast under 400 °C, β phase is pulled and overridden by α phase under this temperature. When the temperature increases to 500 °C, which is higher than β phase transition temperature, the flow velocity of β phase increases, and the deformation of β phase is found to bulge. The flow of β phase is more sensitive to low deformation rates than α phase. The deformation amount has a more significant impact on β phase than α phase, and the deformation of β phase promotes the grain fragmentation and refinement of α phase accompanied by huge β phase bulging obviously. Under the conditions of high temperature, low deformation rate, and large deformation amount, both phase α and β of up-drawing continuous casting brass alloy are broken and the grains are refined. Based on the two-phase flow characteristic, numerical simulation is used to obtain the optimal continuous extrusion parameters of the H-shaped wire of up-drawing continuous casting H62 brass. Then, the optimized complex cross-section wire is prepared by continuous extrusion experiment. This research aims to provide guidance for the complex processing of two-phase alloys.
Seismic node is an important geological exploration equipment. The seismic node has a complex near-ground application environment. The near-ground seriously interferes with the wireless signal of the ...seismic node and affects its data transmission capability. This article proposes a link and energy-aware gradient routing (LEGR) method, which can effectively reduce the interference of the near-ground on the seismic node. LEGR introduces the concept of link potential energy (LPE) to represent the gradient and establishes the LPE loss model using the link quality and the remaining power. The LPE is generated by the data acquisition center (DAC) and spreads to each node with some loss which is depending on the LPE loss model during the propagation process, and finally, a gradient field about the LPE is formed. Data are transmitted along the steepest direction of the gradient to the DAC. The simulation results show that LEGR significantly reduces the impact of wireless signal strength fluctuations on the seismic node compared with other traditional routing methods. The experimental results show that LEGR is superior to the commonly used routing method for seismic nodes network in term of packets latency and packet delivery rate, improves the anti-interference ability, and enhances the wireless communication reliability for the seismic node networks.
Arteriosclerosis obliterans (ASO) is a limb manifestation of large vessel atherosclerosis. Phenotype switching of vascular smooth muscle cells (VSMCs) occurs in the course of the pathological ...process. The underlying mechanism of SMCs proliferation remains unclear. Several studies have demonstrated that the dysregulation of long non-coding RNA (lncRNAs) plays a pivotal part in the progression of ASO by exacerbating the proliferation of VSMCs. Based on the endogenous competitive RNA (ceRNA) hypothesis, the mechanism of lncRNAs involved in the pathology of VSMCs was exposed, while the entire map of the regulatory network remains to be elucidated. In the current study, genes and the lncRNAs modules that are relevant to the clinical trait were confirmed through weighted gene co-expression network analysis (WGCNA). In this study, we comprehensively constructed a specific lncRNAs-mediated ceRNA and RBP network. The three lncRNAs,
HMGA1P4, C5orf66
, and
AC148477.2
, influenced the proliferation of VSMCs and were found to be associated with the immune landscape, thus they were ultimately screened out. Further verification revealed that
AC147488.2
was significantly down-regulated in both ASO arteries and all stages of proliferative VSMCs, which implied that
AC147488.2
might have a significant impact on ASO. This finding would improve our understanding of the epigenetic regulation of ASO and unravel novel diagnostic and therapeutic targets.
Syncope belongs to the transient loss of consciousness (TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting ...for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society (CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association (CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association (CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association (CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association (BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and head-up tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.
The three-dimensional (3D) and two-dimensional (2D) chiral metamaterials (CMMs) have been proved to exhibit circular dichroism and circular conversion dichroism, respectively. The layer-by-layer ...chiral metamaterials, as a category of 3D CMMs, are expected to show the same properties as bulk 3D structures (e.g. helices). However, in this paper, we demonstrated that the layer-by-layer CMMs exhibit circular dichroism and circular conversion dichroism simultaneously by using both theoretical and experimental methods. This work showed that asymmetric transmissions of circular polarizations can also be observed in layer-by-layer CMMs. Moreover, we provided some necessary requirements for the existing of asymmetric transmissions in layer-by-layer CMMs.
In this paper, a double-layer split-ring resonator structure chiral metamaterial was proposed which could exhibit pronounced circular dichroism (CD) effect and negative refractive index at microwave ...frequencies. Experiment and simulation calculations are in good agreement. The retrieved effective electromagnetic parameters indicate that the lower frequency CD effect is associated with the negative refractive index property of the left circularly polarized (LCP) wave, and the upper one is to the right circularly polarized (RCP) wave. The mechanism of the giant CD effect could be further illustrated by simulated surface current and power loss density distributions.
A20, a negative regulator of nuclear factor κB signaling, has been shown to attenuate atherosclerotic events. Transforming growth factor beta-activated kinase 1 (TAK1) plays a critical role in ...TNFα-induced atherosclerosis via endothelial nitric oxide (NO) synthase (eNOS) uncoupling and NO reduction. In the study, we investigated the hypothesis that A20 protected endothelial cell injury induced by TNFα through modulating eNOS activity and TAK1 signalling. Human umbilical vein endothelial cells (HUVECs) were stimulated by TNFα. The impact of A20 on cell apoptosis, eNOS expression and NO production and related TAK1 pathway were detected. Both eNOS and NO production were remarkably reduced. TAK1, p38 MAPK phosphorylation and HUVECs apoptosis were enhanced after TNFα stimulation for 2 hrs. Inhibition of A20 significantly activated TAK1, p38 MAPK phosphorylation, and cell apoptosis, but blocked eNOS expression and NO production. Furthermore, p38 MAPK expression was suppressed by A20 over-expression, but re-enhanced by inhibiting A20 or activation of TAK1. Furtherly, TNFα-induced suppression of eNOS and NO production were largely prevented by silencing p38 MAPK. Collectively, our results suggested that A20-mediated TAK1 inactivation suppresses p38 MAPK and regulated MAPK/eNOS pathway, which contributes to endothelial cell survival and function preservation.
We studied both numerically and experimentally electromagnetic behaviors of a bilayered metal helical structure in the microwave-frequency. Two resonances are found in the transmission spectrum of ...the circularly polarized wave which has the same handedness with the helices. The resonance frequencies are almost independent on the distance between the two layers. In addition, the center frequency of full width at half-maximum (FWHM) in the transmission spectrum is approximately inversely proportional to the distance between the two layers.
In the domain of supervised scene flow estimation, the process of manual labeling is both time-intensive and financially demanding. This paper introduces SSFlowNet, a semi-supervised approach for ...scene flow estimation, that utilizes a blend of labeled and unlabeled data, optimizing the balance between the cost of labeling and the precision of model training. SSFlowNet stands out through its innovative use of pseudo-labels, mainly reducing the dependency on extensively labeled datasets while maintaining high model accuracy. The core of our model is its emphasis on the intricate geometric structures of point clouds, both locally and globally, coupled with a novel spatial memory feature. This feature is adept at learning the geometric relationships between points over sequential time frames. By identifying similarities between labeled and unlabeled points, SSFlowNet dynamically constructs a correlation matrix to evaluate scene flow dependencies at individual point level. Furthermore, the integration of a flow consistency module within SSFlowNet enhances its capability to consistently estimate flow, an essential aspect for analyzing dynamic scenes. Empirical results demonstrate that SSFlowNet surpasses existing methods in pseudo-label generation and shows adaptability across varying data volumes. Moreover, our semi-supervised training technique yields promising outcomes even with different smaller ratio labeled data, marking a substantial advancement in the field of scene flow estimation.