As changes in hard or soft oral tissues normally have a microbiological component, it is important to develop diagnostic techniques that support clinical evaluation, without destroying ...microbiological formation. The optical coherence tomography (OCT) represents an alternative to analyze tissues and microorganisms without the need for processing. This imaging technique could be defined as a fast, real-time, in situ, and non-destructive method. Thus, this study proposed the use of the OCT to visualize biofilm by Candida albicans in reline resins for removable prostheses. Three reline resins (Silagum-Comfort, Coe-Comfort, and Soft-Confort), with distinct characteristics related to water sorption and fungal inhibition were used. A total of 30 samples (10 for each resin group) were subjected to OCT scanning before and 96 h after inoculation with Candida albicans (URM 6547). The biofilm analysis was carried out through a 2D optical Callisto SD-OCT (930 nm) operated in the spectral domain. Then, the images were preprocessed using a Formula: see text Gaussian filter to remove the noise, and then Otsu binarization, allowing segmentation and pixel counting. The layer’s biofilm formed was clearly defined and, indeed, its visualization is modified by water sorption of each material. Silagum-Comfort and Soft-Confort showed some similarities in the scattering of light between the clean and inoculated samples, in which, the latter samples presented higher values of light signal intensity. Coe-Comfort samples were the only ones that showed no differences between the clean or inoculated images. Therefore, the results of this study suggest that OCT is a viable technique to visualize the biofilm in reline materials. Because findings in the literature are still scarcely using the OCT technique to visualize biofilm in reline resins, further studies are encouraged. It should not contain any references or displayed equations.
Protein–polysaccharide coacervates formation was evaluated under influence of pH (3.0, 4.0, 6.5, 8.5 and 10.0), temperature (10, 20, 30, 40 and 50 °C) and polysaccharide mass (0.025, 0.033 and ...0.050 g). It was possible to observe that solutions with lower turbidity values were found in pH band 3.0 to 4.0. Statistical analysis of turbidity data have shown that for all polymers pH was meaningful in coacervate formation, although for some, besides pH, temperature and polymer concentration could also influence significantly (p < 0,05) in coacervate formation. Encapsulates morphology made by coacervation was directly linked to the kind of polymer used and its interactional degree. Dehydrated coacervates have presented heterogeneous morphology, different from their original structures.
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Objective
The present study aimed to determine whether physical activity and energy intake are associated with the anthropometric and blood cardiovascular risk factors alterations in women living in ...social vulnerability for a period of 2 years.
Methods
The study was carried out with women residing in the outskirts of Maceió‐AL, aged between 19 and 45 years. We characterized the socioeconomic and biochemical profile (glucose, insulin, and blood lipids) at the beginning and at the end of the study. Anthropometric evaluation was performed in three moments: at the beginning, and after 1 and 2 years of follow‐up. Energy expenditure, measured by doubly labeled water, physical activity, measured by 7‐day triaxial accelerometry, and energy intake, measured by 3‐day 24‐hour food recall, were collected at baseline.
Results
After 2 years, 34 women were completely assessed, with a mean age of 33.7 years. Women spent around 16 hours of the day sitting/lying down. There was an increase in body weight (from 64.61 ± 11.69 to 66.37 ± 13.26 kg, P < .01), which was not associated with any of the predictors. There was also an increase in waist/hip ratio (WHR) (from 0.84 ± 0.07 to 0.87 ± 0.05, P < .01), which was positively associated with the amount of sitting/lying time per day. There were no significant alterations in blood cardiovascular risk factors.
Conclusion
Energy intake did not predict anthropometrical changes. Sitting/lying time was associated with an increase in WHR, but not in body weight or blood cardiovascular risk factors in low‐income women.
Childhood pemphigus vulgaris (CPV) is an uncommon disease involving the skin and mucous membranes, and few cases of CPV have been reported. This study reports a case of a 5-year-old male patient with ...oral lesions since he had 3 years old. In the clinical examination, he presented buccal opening limitation, hoarseness, healed lesions in the skin, and painless ulcers in oral, genital, and ocular mucosa. The oral lesions involved lips, labial mucosa, tongue, palate, oral commissures, lower alveolar mucosa, buccal mucosa, and gum. Posteriorly, videolaryngoscopy showed lesions in the pharynx and larynx. An incisional biopsy and direct immunofluorescence from a sample of the lower lip mucosa was performed, which confirmed the diagnosis of CPV. The patient was treated with systemic medication, which improved his clinical conditional. However, the lesions remain in labial mucosa and ventral surface of the tongue. The patient has a clinical follow-up of 2 years.
During the onset of the COVID-19 pandemic, the COVIDiSTRESS Consortium launched an open-access global survey to understand and improve individuals' experiences related to the crisis. A year later, we ...extended this line of research by launching a new survey to address the dynamic landscape of the pandemic. This survey was released with the goal of addressing diversity, equity, and inclusion by working with over 150 researchers across the globe who collected data in 48 languages and dialects across 137 countries. The resulting cleaned dataset described here includes 15,740 of over 20,000 responses. The dataset allows cross-cultural study of psychological wellbeing and behaviours a year into the pandemic. It includes measures of stress, resilience, vaccine attitudes, trust in government and scientists, compliance, and information acquisition and misperceptions regarding COVID-19. Open-access raw and cleaned datasets with computed scores are available. Just as our initial COVIDiSTRESS dataset has facilitated government policy decisions regarding health crises, this dataset can be used by researchers and policy makers to inform research, decisions, and policy.
Peripherally Inserted Central Catheters (PICC) consist of an intravenous device widely used in neonates in intensive care units, characterizing a procedure that is related to a long repertoire of ...complications that can intensify neonatal morbidity and mortality. The study aims to review and analyze the factors associated with complications resulting from the use of peripherally inserted central catheter in neonates. Method: This is a bibliographic, descriptive analysis, of the integrative literature review type, with searches carried out in the Scientific Electronic Library Online (SciELO) and PubMed databases. Eight complete articles were selected, available in open access in Portuguese and English and published in the years 2018 to 2022. Results: From the analysis of the classes, three categories emerged: Class 1- Risk Factors Associated with PICC Use, Class 2 - Complications Deriving from the use of the PICC, Class 3 - Professional Training against the Maintenance of the PICC. Conclusion: it was evidenced that care related to the insertion and maintenance of the PICC is mainly directed to the control of nosocomial infection, highlighting the adherence to aseptic techniques for handling the catheter, performing the dressing and proper hand hygiene.
