We propose a versatile framework to dynamically generate Floquet higher-order topological insulators by multistep driving of topologically trivial Hamiltonians. Two analytically solvable examples are ...used to illustrate this procedure to yield Floquet quadrupole and octupole insulators with zero- and/or π-corner modes protected by mirror symmetries. Furthermore, we introduce dynamical topological invariants from the full unitary return map and show its phase bands contain Weyl singularities whose topological charges form dynamical multipole moments in the Brillouin zone. Combining them with the topological index of a Floquet Hamiltonian gives a pair of Z_{2} invariant ν_{0} and ν_{π} which fully characterize the higher-order topology and predict the appearance of zero- and π-corner modes. Our work establishes a systematic route to construct and characterize Floquet higher-order topological phases.
Topological insulators are classified according to their symmetries. Discovery of them in electronic solids is thus restricted by orbital and crystalline symmetries available in nature. Synthetic ...quantum matter, such as the recent double-well optical lattices loaded with s and p orbital ultracold atoms, can exploit symmetries and interaction beyond natural conditions. Here we unveil a topological phase of interacting fermionic atoms on a two-leg ladder derived from the above experimental optical lattice by dimension reduction. The topological band structure originates from the staggered phases of sp orbital tunnelling, requiring neither spin-orbit coupling nor other known mechanisms like p-wave pairing, artificial gauge field or rotation. Upon crossing over to two-dimensional coupled ladders, the edge modes from individual ladder form a parity-protected flat band at zero energy. Experimental signatures are found in density correlations and phase transitions to trivial band and Mott insulators.
Higher-order topological insulators (HOTIs) have emerged as a new class of phases, whose robust in-gap "corner" modes arise from the bulk higher-order multipoles beyond the dipoles in conventional ...topological insulators. Here, we incorporate Floquet driving into HOTIs, and report for the first time a dynamical polarization theory with anomalous nonequilibrium multipoles. Further, a proposal to detect not only corner states but also their dynamical origin in cold atoms is demonstrated, with the latter one never achieved before. Experimental determination of anomalous Floquet corner modes is also proposed.
The orbital degree of freedom plays a fundamental role in understanding the unconventional properties in solid state materials. Experimental progress in quantum atomic gases has demonstrated that ...high orbitals in optical lattices can be used to construct quantum emulators of exotic models beyond natural crystals, where novel many-body states such as complex Bose-Einstein condensates and topological semimetals emerge. A brief introduction of orbital degrees of freedom in optical lattices is given and a summary of exotic orbital models and resulting many-body phases is provided. Experimental consequences of the novel phases are also discussed.
The importance of transitioning the strategy for slowing the spread of the COVID-19 pandemic in the U.S. from containment to mitigation is discussed. The need for clear guidelines shared across ...hospitals and states is suggested to help improve the ability to maintain a capable and sustainable approach for all patients.
Time crystals, a phase showing spontaneous breaking of time-translation symmetry, has been an intriguing subject for systems far away from equilibrium. Recent experiments found such a phase in both ...the presence and the absence of localization, while in theories localization by disorder is usually assumed a priori. In this work, we point out that time crystals can generally exist in systems without disorder. A series of clean quasi-one-dimensional models under Floquet driving are proposed to demonstrate this unexpected result in principle. Robust time crystalline orders are found in the strongly interacting regime along with the emergent integrals of motion in the dynamical system, which can be characterized by level statistics and the out-of-time-ordered correlators. We propose two cold atom experimental schemes to realize the clean Floquet time crystals, one by making use of dipolar gases and another by synthetic dimensions.
This case series characterizes the demographics, health services use, and vital status and discharge dispositions of patients with polymerase chain reaction–confirmed coronavirus disease 2019 ...(COVID-19) hospitalized in the Kaiser Permanente Northern California health system in March 2020.
Spontaneous symmetry breaking underlies much of our classification of phases of matter and their associated transitions
. The nature of the underlying symmetry being broken determines many of the ...qualitative properties of the phase; this is illustrated by the case of discrete versus continuous symmetry breaking. Indeed, in contrast to the discrete case, the breaking of a continuous symmetry leads to the emergence of gapless Goldstone modes controlling, for instance, the thermodynamic stability of the ordered phase
. Here, we realize a two-dimensional dipolar XY model that shows a continuous spin-rotational symmetry using a programmable Rydberg quantum simulator. We demonstrate the adiabatic preparation of correlated low-temperature states of both the XY ferromagnet and the XY antiferromagnet. In the ferromagnetic case, we characterize the presence of a long-range XY order, a feature prohibited in the absence of long-range dipolar interaction. Our exploration of the many-body physics of XY interactions complements recent works using the Rydberg-blockade mechanism to realize Ising-type interactions showing discrete spin rotation symmetry
.
Prior sepsis studies evaluating antibiotic timing have shown mixed results.
To evaluate the association between antibiotic timing and mortality among patients with sepsis receiving antibiotics within ...6 hours of emergency department registration.
Retrospective study of 35,000 randomly selected inpatients with sepsis treated at 21 emergency departments between 2010 and 2013 in Northern California. The primary exposure was antibiotics given within 6 hours of emergency department registration. The primary outcome was adjusted in-hospital mortality. We used detailed physiologic data to quantify severity of illness within 1 hour of registration and logistic regression to estimate the odds of hospital mortality based on antibiotic timing and patient factors.
The median time to antibiotic administration was 2.1 hours (interquartile range, 1.4-3.1 h). The adjusted odds ratio for hospital mortality based on each hour of delay in antibiotics after registration was 1.09 (95% confidence interval CI, 1.05-1.13) for each elapsed hour between registration and antibiotic administration. The increase in absolute mortality associated with an hour's delay in antibiotic administration was 0.3% (95% CI, 0.01-0.6%; P = 0.04) for sepsis, 0.4% (95% CI, 0.1-0.8%; P = 0.02) for severe sepsis, and 1.8% (95% CI, 0.8-3.0%; P = 0.001) for shock.
In a large, contemporary, and multicenter sample of patients with sepsis in the emergency department, hourly delays in antibiotic administration were associated with increased odds of hospital mortality even among patients who received antibiotics within 6 hours. The odds increased within each sepsis severity strata, and the increased odds of mortality were greatest in septic shock.
...there has also been enormous interest in applying AI to health care and, in particular, to data-rich environments like the intensive care unit. With its highly touted AI—the car’s technology ...deploys sensors, computer vision, and deep learning to drive under its own guidance—having logged billions of driving miles, I anticipated a seamless transition between myself and the vehicle. ...algorithms are trained using existing data and, thus, encode prior decisions and biases within them. Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
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