Three-dimensional topological insulators are a new state of quantum matter with a bulk gap and odd number of relativistic Dirac fermions on the surface. By investigating the surface state of Bi2Te3 ...with angle-resolved photoemission spectroscopy, we demonstrate that the surface state consists of a single nondegenerate Dirac cone. Furthermore, with appropriate hole doping, the Fermi level can be tuned to intersect only the surface states, indicating a full energy gap for the bulk states. Our results establish that Bi2Te3 is a simple model system for the three-dimensional topological insulator with a single Dirac cone on the surface. The large bulk gap of Bi2Te3 also points to promising potential for high-temperature spintronics applications.
Realizing quantum speedup for practically relevant, computationally hard problems is a central challenge in quantum information science. Using Rydberg atom arrays with up to 289 qubits in two spatial ...dimensions, we experimentally investigate quantum algorithms for solving the Maximum Independent Set problem. We use a hardware-efficient encoding associated with Rydberg blockade, realize closed-loop optimization to test several variational algorithms, and subsequently apply them to systematically explore a class of graphs with programmable connectivity. We find the problem hardness is controlled by the solution degeneracy and number of local minima, and experimentally benchmark the quantum algorithm's performance against classical simulated annealing. On the hardest graphs, we observe a superlinear quantum speedup in finding exact solutions in the deep circuit regime and analyze its origins.
Background
The aim of this study was to investigate the prevalence of epidemiologic and physician‐diagnosed pollen‐induced AR (PiAR) in the grasslands of northern China and to study the impact of the ...intensity and time of pollen exposure on PiAR prevalence.
Methods
A multistage, clustered and proportionately stratified random sampling with a field interviewer‐administered survey study was performed together with skin prick tests (SPT) and measurements of the daily pollen count.
Results
A total of 6043 subjects completed the study, with a proportion of 32.4% epidemiologic AR and 18.5% PiAR. The prevalence was higher in males than females (19.6% vs 17.4%, P = .024), but no difference between the two major residential and ethnic groups (Han and Mongolian) was observed. Subjects from urban areas showed higher prevalence of PiAR than rural areas (23.1% vs 14.0%, P < .001). Most PiAR patients were sensitized to two or more pollens (79.4%) with artemisia, chenopodium, and humulus scandens being the most common pollen types, which were similarly found as the top three sensitizing pollen allergens by SPT. There were significant regional differences in the prevalence of epidemiologic AR (from 18.6% to 52.9%) and PiAR (from 10.5% to 31.4%) among the six areas investigated. PiAR symptoms were positively associated with pollen counts, temperature, and precipitation (P < .05), but negatively with wind speed and pressure P < .05).
Conclusion
Pollen‐induced AR (PiAR) prevalence in the investigated region is extremely high due to high seasonal pollen exposure, which was influenced by local environmental and climate conditions.
Using Time History of Events and Macroscale Interactions during Substorms observations from four tail seasons, we study the three‐dimensional structure of the dipolarization front current sheet ...(DFCS), which demarcates the magnetic boundary of a dipolarizing flux bundle (DFB, the strong magnetic field region led by a dipolarization front) in Earth's magnetotail. An equatorial cross section of the DFCS is convex; a meridional cross section is consistent with a dipolarized field line. The equatorial flow pattern in the ambient plasma ahead of the DFCS exhibits diversions of opposite sense on its evening and morning sides. The magnetic field perturbations are consistent with local field‐aligned current generation of region‐2 sense ahead of the front and region‐1 sense at the front. The median thickness of the DFCS increases from 800 to 2000 km with increasing distance from the neutral sheet, indicating bundle compression near the neutral sheet. On a meridional cross section, DFCS's linear current density (1.2–1.8 nA/m) peaks ~±0.55 l from the neutral sheet (where l is the ambient cross‐tail current sheet half‐thickness, l ~1.5 RE in our database). This peak, reminiscent of active‐time cross‐tail current sheet bifurcation noted in past studies, suggests that the intense but thin DFCS (10 to 20 nA/m2) may be produced by redistribution (diversion) of the extended but weaker cross‐tail current (~1 nA/m2). Near the neutral sheet, the average DFCS current over the dipolarization front (DF) thickness is perpendicular to both the magnetic field interior to the DFB and the average field direction over the DF thickness. Away from the neutral sheet, the average current becomes progressively parallel to the internal field and the average field direction. The average current directions are indicative of region‐1‐sense field‐aligned current on the DF. As few as approximately three DFBs can carry sufficient total current that, if redirected into the auroral ionosphere, can account for the substorm current wedge's peak current for a sizable substorm (~1 MA). A collapsing DFB could thus be an elemental substorm current wedge, or “wedgelet,” that can divert a sizable portion of the cross‐tail current into the auroral ionosphere.
Key Points
The dipolarization front has the shape of a saddleThe dipolarization front current has field‐aligned components in region‐1 senseThe dipolarization front thickness and current density varies with location
Establishing the appropriate theoretical framework for unconventional superconductivity in the iron-based materials requires correct understanding of both the electron correlation strength and the ...role of Fermi surfaces. This fundamental issue becomes especially relevant with the discovery of the iron chalcogenide superconductors. Here, we use angle-resolved photoemission spectroscopy to measure three representative iron chalcogenides, FeTe0.56Se0.44, monolayer FeSe grown on SrTiO3 and K0.76Fe1.72Se2. We show that these superconductors are all strongly correlated, with an orbital-selective strong renormalization in the dxy bands despite having drastically different Fermi surface topologies. Furthermore, raising temperature brings all three compounds from a metallic state to a phase where the dxy orbital loses all spectral weight while other orbitals remain itinerant. These observations establish that iron chalcogenides display universal orbital-selective strong correlations that are insensitive to the Fermi surface topology, and are close to an orbital-selective Mott phase, hence placing strong constraints for theoretical understanding of iron-based superconductors.
Families and genera assigned to Tremellomycetes have been mainly circumscribed by morphology and for the yeasts also by biochemical and physiological characteristics. This phenotype-based ...classification is largely in conflict with molecular phylogenetic analyses. Here a phylogenetic classification framework for the Tremellomycetes is proposed based on the results of phylogenetic analyses from a seven-genes dataset covering the majority of tremellomycetous yeasts and closely related filamentous taxa. Circumscriptions of the taxonomic units at the order, family and genus levels recognised were quantitatively assessed using the phylogenetic rank boundary optimisation (PRBO) and modified general mixed Yule coalescent (GMYC) tests. In addition, a comprehensive phylogenetic analysis on an expanded LSU rRNA (D1/D2 domains) gene sequence dataset covering as many as available teleomorphic and filamentous taxa within Tremellomycetes was performed to investigate the relationships between yeasts and filamentous taxa and to examine the stability of undersampled clades. Based on the results inferred from molecular data and morphological and physiochemical features, we propose an updated classification for the Tremellomycetes. We accept five orders, 17 families and 54 genera, including seven new families and 18 new genera. In addition, seven families and 17 genera are emended and one new species name and 185 new combinations are proposed. We propose to use the term pro tempore or pro tem. in abbreviation to indicate the species names that are temporarily maintained.
Three-dimensional (3D) topological Dirac semimetals (TDSs) represent an unusual state of quantum matter that can be viewed as "3D graphene." In contrast to 2D Dirac fermions in graphene or on the ...surface of 3D topological insulators, TDSs possess 3D Dirac fermions in the bulk. By investigating the electronic structure of Na3Bi with angle-resolved photoemission spectroscopy, we detected 3D Dirac fermions with linear dispersions along all momentum directions. Furthermore, we demonstrated the robustness of 3D Dirac fermions in Na3Bi against in situ surface doping. Our results establish Na3Bi as a model system for 3D TDSs, which can serve as an ideal platform for the systematic study of quantum phase transitions between rich topological quantum states.
Recent observations have suggested that spatially localized flows of high‐temperature, low‐density plasma carrying a dipolarized magnetic field (dipolarizing flux bundles, DFBs) play a key role in ...hot plasma transport toward the inner magnetosphere. What controls plasma heating in DFBs and how do thermodynamic parameters (such as density, temperature, pressure, and specific entropy) and spectral properties of the DFB population depend on ambient plasma sheet properties and geocentric distance R remains unknown. By statistical analysis of 271 DFB events detected by the Time History of Events and Macroscale Interactions during Substorms mission during the 2008–2009 tail seasons, we find that on average, plasma inside DFBs is a factor of 0.6 less dense and a factor of 1.5 to 2 hotter than ambient tail plasma. The radial profiles of average thermodynamic parameters inside and outside DFBs are similar; when fitted by the κ‐function, their energy spectra have similar κ‐exponents, but a factor of 2 larger peak energies inside DFBs. Our analysis suggests that average DFB plasma properties are closely linked to those of the ambient plasma sheet population. Estimations show that on average, adiabatic heating of the ambient plasma in the increased magnetic field is the major factor in DFB plasma heating.
Key Points
Statistical analysis of THEMIS observations
Dependences between plasma parameters inside and outside DFBs
Adiabatic heating is the main mechanism of plasma thermalization in DFBs
Dapsone is an important medication for the treatment of leprosy, but a life-threatening drug hypersensitivity syndrome develops in some patients. In this report from China, an
HLA-B
locus is ...identified as a strong genetic risk factor for the syndrome.
Dapsone (4-4′-sulfonyldianiline), which was first synthesized in 1908,
1
is both an antibiotic and an antiinflammatory agent. Dapsone alone or in combination with other drugs has been used for the prevention and treatment of infectious diseases (e.g., leprosy, malaria, and actinomycetoma, as well as
Pneumocystis jirovecii
pneumonia in persons with human immunodeficiency virus HIV infection) and chronic inflammatory diseases characterized by the infiltration of neutrophils or eosinophils (e.g., dermatitis herpetiformis, linear IgA dermatosis, subcorneal pustular dermatosis, and erythema elevatum diutinum).
2
,
3
About 0.5 to 3.6% of persons treated with dapsone have a drug hypersensitivity syndrome,
3
–
5
which was first described by . . .
Three-dimensional (3D) topological Dirac semimetals (TDSs) are a recently proposed state of quantum matter that have attracted increasing attention in physics and materials science. A 3D TDS is not ...only a bulk analogue of graphene; it also exhibits non-trivial topology in its electronic structure that shares similarities with topological insulators. Moreover, a TDS can potentially be driven into other exotic phases (such as Weyl semimetals, axion insulators and topological superconductors), making it a unique parent compound for the study of these states and the phase transitions between them. Here, by performing angle-resolved photoemission spectroscopy, we directly observe a pair of 3D Dirac fermions in Cd3As2, proving that it is a model 3D TDS. Compared with other 3D TDSs, for example, β-cristobalite BiO2 (ref. 3) and Na3Bi (refs 4, 5), Cd3As2 is stable and has much higher Fermi velocities. Furthermore, by in situ doping we have been able to tune its Fermi energy, making it a flexible platform for exploring exotic physical phenomena.